SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gji'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
4 / 4 ILE A 165
LEU A 162
VAL A 158
ALA A 151
None
0.78A 1mz9A-4gjiA:
undetectable
1mz9A-4gjiA:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
4 / 5 ILE A 165
LEU A 162
VAL A 158
ALA A 151
None
0.73A 1mz9C-4gjiA:
undetectable
1mz9C-4gjiA:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
3 / 3 ASP A   9
LYS A   4
ARG A 414
None
1.06A 1ra8A-4gjiA:
undetectable
1ra8A-4gjiA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XID_A_ASCA389_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
6 / 10 TRP A  57
PHE A 131
TRP A 179
GLU A 219
HIS A 257
ASP A 327
RNS  A1001 (-3.5A)
None
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
0.36A 1xidA-4gjiA:
34.2
1xidA-4gjiA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
5 / 12 TRP A  57
PHE A 131
TRP A 179
LYS A 221
ASP A 289
RNS  A1001 (-3.5A)
None
RNS  A1001 (-3.3A)
RNS  A1001 (-2.7A)
MN  A1004 ( 2.6A)
1.02A 1xihA-4gjiA:
34.3
1xihA-4gjiA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
6 / 12 TRP A  57
PHE A 131
TRP A 179
LYS A 221
HIS A 257
ASP A 327
RNS  A1001 (-3.5A)
None
RNS  A1001 (-3.3A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
0.33A 1xihA-4gjiA:
34.3
1xihA-4gjiA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
4 / 7 ASP A 124
SER A  99
GLN A 328
TRP A  57
None
None
None
RNS  A1001 (-3.5A)
0.95A 2cmlA-4gjiA:
undetectable
2cmlA-4gjiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
4 / 8 ASP A 124
SER A  99
GLN A 328
TRP A  57
None
None
None
RNS  A1001 (-3.5A)
0.80A 2cmlB-4gjiA:
undetectable
2cmlB-4gjiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
4 / 8 ASP A 124
SER A  99
GLN A 328
TRP A  57
None
None
None
RNS  A1001 (-3.5A)
0.92A 2cmlD-4gjiA:
undetectable
2cmlD-4gjiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
4 / 7 ALA A 404
THR A 405
ALA A 408
ARG A  13
None
0.90A 2ql8A-4gjiA:
undetectable
2ql8B-4gjiA:
undetectable
2ql8A-4gjiA:
16.92
2ql8B-4gjiA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
5 / 12 ALA A 294
LEU A 302
PHE A 306
ALA A 349
GLN A  89
None
0.88A 2ve3A-4gjiA:
undetectable
2ve3A-4gjiA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
ASP A 289
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
0.76A 2xinA-4gjiA:
33.8
2xinA-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
0.30A 2xinA-4gjiA:
33.8
2xinA-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
ASP A 289
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
0.89A 2xinB-4gjiA:
33.7
2xinB-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
0.31A 2xinB-4gjiA:
33.7
2xinB-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
ASP A 289
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
0.83A 2xinC-4gjiA:
33.8
2xinC-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
0.33A 2xinC-4gjiA:
33.8
2xinC-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
ASP A 289
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
0.88A 2xinD-4gjiA:
33.7
2xinD-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
0.29A 2xinD-4gjiA:
33.7
2xinD-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
4 / 7 TYR A 199
GLU A 219
LEU A 146
ASN A 161
None
MN  A1003 ( 2.6A)
None
None
1.42A 3k8mB-4gjiA:
5.1
3k8mB-4gjiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
5 / 12 GLN A 250
GLY A 275
ARG A 358
GLY A 319
ALA A 312
None
1.03A 3sudA-4gjiA:
undetectable
3sudA-4gjiA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
5 / 12 GLN A 250
GLY A 275
ARG A 358
GLY A 319
ALA A 312
None
1.09A 3sueB-4gjiA:
undetectable
3sueB-4gjiA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
6 / 12 TRP A  57
TRP A 179
LYS A 221
HIS A 257
ASP A 289
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
0.47A 3ximA-4gjiA:
33.8
3ximA-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
7 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 289
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
0.54A 3ximB-4gjiA:
33.7
3ximB-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
7 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 289
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
0.50A 3ximC-4gjiA:
34.0
3ximC-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
7 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 289
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
0.49A 3ximD-4gjiA:
33.9
3ximD-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
5 / 11 SER A 409
GLY A 410
ILE A  88
ILE A 336
ASP A 334
None
0.93A 4dt8A-4gjiA:
undetectable
4dt8A-4gjiA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
5 / 10 SER A 409
GLY A 410
ILE A  88
ILE A 336
ASP A 334
None
1.03A 4dt8B-4gjiA:
undetectable
4dt8B-4gjiA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
5 / 12 TRP A  57
TRP A 179
LYS A 221
HIS A 257
ASP A 289
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
0.48A 4dvoA-4gjiA:
34.2
4dvoA-4gjiA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
5 / 11 SER A 218
GLU A 219
LEU A 255
LEU A 277
GLY A 279
None
MN  A1003 ( 2.6A)
None
None
None
1.48A 4foxC-4gjiA:
undetectable
4foxC-4gjiA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
5 / 10 ALA A 249
LEU A 216
VAL A 178
ILE A 165
ALA A 202
None
1.11A 4j14A-4gjiA:
undetectable
4j14A-4gjiA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
5 / 12 TRP A  57
TRP A 179
LYS A 221
HIS A 257
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
0.29A 4xiaA-4gjiA:
33.8
4xiaA-4gjiA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
0.33A 4xiaB-4gjiA:
33.9
4xiaB-4gjiA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_D_ACTD403_0
(PROTON-GATED ION
CHANNEL)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
4 / 4 ILE A  40
ARG A 395
TYR A  26
GLU A 391
None
1.40A 4zzbD-4gjiA:
undetectable
4zzbD-4gjiA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
4 / 8 TRP A 179
GLU A 219
ASP A 291
TRP A  57
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
MN  A1004 ( 3.9A)
RNS  A1001 (-3.5A)
1.02A 5kgpA-4gjiA:
undetectable
5kgpA-4gjiA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
4 / 8 TRP A 179
GLU A 219
ASP A 291
TRP A  57
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
MN  A1004 ( 3.9A)
RNS  A1001 (-3.5A)
1.04A 5kgpB-4gjiA:
undetectable
5kgpB-4gjiA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_A_SORA503_0
(XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
5 / 9 TRP A  57
TRP A 179
GLU A 219
HIS A 257
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
0.40A 5nhaA-4gjiA:
31.1
5nhaA-4gjiA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_B_SORB503_0
(XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
5 / 9 TRP A  57
TRP A 179
GLU A 219
HIS A 257
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
0.39A 5nhaB-4gjiA:
31.1
5nhaB-4gjiA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_C_SORC503_0
(XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
5 / 9 TRP A  57
TRP A 179
GLU A 219
HIS A 257
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
0.39A 5nhaC-4gjiA:
31.1
5nhaC-4gjiA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
5 / 9 TRP A  57
TRP A 179
GLU A 219
HIS A 257
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
0.40A 5nhaD-4gjiA:
31.0
5nhaD-4gjiA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_2
(RIBOFLAVIN LYASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
4 / 4 ASN A 283
GLN A 328
ASP A 327
THR A 177
None
None
RNS  A1001 ( 2.8A)
None
1.36A 5w4zB-4gjiA:
7.0
5w4zB-4gjiA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
7 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 289
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
0.55A 5ximA-4gjiA:
33.9
5ximA-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
6 / 12 TRP A  57
TRP A 179
LYS A 221
HIS A 257
ASP A 289
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
0.63A 5ximB-4gjiA:
33.7
5ximB-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
7 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 289
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
0.62A 5ximC-4gjiA:
33.8
5ximC-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
7 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 289
ASP A 327
RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
0.56A 5ximD-4gjiA:
33.6
5ximD-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
5 / 12 TYR A 199
LEU A 200
HIS A 220
LEU A 216
ALA A 249
None
1.22A 6djzA-4gjiA:
undetectable
6djzA-4gjiA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)
4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri)
3 / 3 THR A  64
GLU A  74
ASN A 331
None
0.50A 6nj9K-4gjiA:
undetectable
6nj9K-4gjiA:
21.50