SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gjp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 4gjp HAX3
(Xanthomonas
campestris) 		4 / 5 PRO A 563
LEU A 527
THR A 547
ARG A 550
 None
 1.40A 1i2wA-4gjpA:
undetectable		 1i2wA-4gjpA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 4gjp HAX3
(Xanthomonas
campestris) 		4 / 5 PRO A 665
LEU A 629
THR A 649
ARG A 652
 None
 1.33A 1i2wA-4gjpA:
undetectable		 1i2wA-4gjpA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 4gjp HAX3
(Xanthomonas
campestris) 		5 / 10 ALA A 298
LEU A 241
SER A 299
LYS A 262
ARG A 249
 None
 1.33A 2ceoB-4gjpA:
undetectable		 2ceoB-4gjpA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4gjp HAX3
(Xanthomonas
campestris) 		4 / 5 VAL A 329
SER A 299
VAL A 295
SER A 333
 None
 1.17A 2j9cA-4gjpA:
undetectable
2j9cB-4gjpA:
undetectable
2j9cC-4gjpA:
undetectable		 2j9cA-4gjpA:
14.23
2j9cB-4gjpA:
14.23
2j9cC-4gjpA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4gjp HAX3
(Xanthomonas
campestris) 		4 / 7 SER A 299
VAL A 295
LYS A 262
SER A 333
 None
 1.20A 2j9cA-4gjpA:
undetectable
2j9cB-4gjpA:
undetectable
2j9cC-4gjpA:
undetectable		 2j9cA-4gjpA:
14.23
2j9cB-4gjpA:
14.23
2j9cC-4gjpA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 4gjp HAX3
(Xanthomonas
campestris) 		5 / 12 GLY A 711
LEU A 681
GLY A 677
ASN A 674
ALA A 717
 None
 1.06A 3vywC-4gjpA:
undetectable		 3vywC-4gjpA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 4gjp HAX3
(Xanthomonas
campestris) 		4 / 4 LEU A 287
LEU A 307
GLN A 326
GLU A 292
 None
 1.16A 4i41A-4gjpA:
undetectable		 4i41A-4gjpA:
19.60