SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gk9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		5 / 9 PHE A 269
VAL A 241
ILE A 179
VAL A 177
ILE A 246
 None
 1.27A 1gebA-4gk9A:
undetectable		 1gebA-4gk9A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		5 / 11 LEU A 244
ALA A 141
ALA A 169
VAL A 177
MET A  30
 None
 1.18A 1hbpA-4gk9A:
3.2		 1hbpA-4gk9A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		4 / 7 ALA A  43
ILE A 113
ASN A  45
ILE A  46
 None
 0.92A 1yc5A-4gk9A:
undetectable		 1yc5A-4gk9A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		4 / 5 PRO A 275
GLY A  38
ASN A  40
GLY A   7
 None
 1.13A 1zlqA-4gk9A:
undetectable		 1zlqA-4gk9A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		4 / 6 TYR A 146
GLY A 252
ASP A 250
ASN A 253
 None
 1.24A 2g72A-4gk9A:
undetectable		 2g72A-4gk9A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		4 / 5 ALA A  43
ILE A 113
ASN A  45
ILE A  46
 None
 0.91A 2h4jA-4gk9A:
undetectable		 2h4jA-4gk9A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		4 / 7 GLY A  29
GLY A  28
VAL A  99
LEU A 232
 None
 0.78A 2oa1B-4gk9A:
undetectable		 2oa1B-4gk9A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		4 / 7 TYR A 128
GLN A 107
TYR A  79
ILE A 113
 None
 1.07A 2ph9A-4gk9A:
undetectable
2ph9B-4gk9A:
undetectable		 2ph9A-4gk9A:
21.65
2ph9B-4gk9A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		5 / 11 PHE A 136
GLY A  29
GLY A  28
ASN A  16
ILE A 230
 None
 1.31A 3owxA-4gk9A:
undetectable
3owxB-4gk9A:
undetectable		 3owxA-4gk9A:
22.73
3owxB-4gk9A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		3 / 3 SER A  21
GLY A  20
GLN A  17
 None
MAN  A 319 (-3.5A)
None
 0.64A 3v4tH-4gk9A:
undetectable		 3v4tH-4gk9A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		3 / 3 SER A  88
GLY A  87
GLN A  84
 None
MAN  A 309 (-3.4A)
None
 0.36A 3v4tH-4gk9A:
undetectable		 3v4tH-4gk9A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		3 / 3 SER A 155
GLY A 154
GLN A 151
 None
MAN  A 304 (-3.5A)
None
 0.27A 3v4tH-4gk9A:
undetectable		 3v4tH-4gk9A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		5 / 12 GLY A  29
GLY A  28
ASN A  16
ILE A 230
PHE A 136
 None
 1.27A 4fglA-4gk9A:
undetectable
4fglB-4gk9A:
undetectable		 4fglA-4gk9A:
22.49
4fglB-4gk9A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		4 / 8 TYR A 212
VAL A 177
ILE A 246
TRP A 165
 None
 0.65A 4jq1B-4gk9A:
undetectable		 4jq1B-4gk9A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		5 / 12 VAL A 214
ALA A 213
TYR A 212
GLY A 180
SER A 206
 None
 1.22A 4mm8A-4gk9A:
undetectable		 4mm8A-4gk9A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		5 / 9 VAL A  81
ALA A  80
TYR A  79
GLY A  57
PHE A  69
 None
 1.35A 4mmbA-4gk9A:
undetectable		 4mmbA-4gk9A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		5 / 9 VAL A 148
ALA A 147
TYR A 146
GLY A 257
PHE A 269
 None
 1.34A 4mmbA-4gk9A:
undetectable		 4mmbA-4gk9A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		5 / 9 VAL A 214
ALA A 213
TYR A 212
GLY A 190
PHE A 202
 None
 1.35A 4mmbA-4gk9A:
undetectable		 4mmbA-4gk9A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		5 / 9 VAL A  81
ALA A  80
TYR A  79
GLY A  57
PHE A  69
 None
 1.39A 4mmfA-4gk9A:
undetectable		 4mmfA-4gk9A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		5 / 9 VAL A 148
ALA A 147
TYR A 146
GLY A 257
PHE A 269
 None
 1.38A 4mmfA-4gk9A:
undetectable		 4mmfA-4gk9A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		5 / 9 VAL A 214
ALA A 213
TYR A 212
GLY A 190
PHE A 202
 None
 1.38A 4mmfA-4gk9A:
undetectable		 4mmfA-4gk9A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		5 / 9 VAL A  81
ALA A  80
TYR A  79
GLY A  57
PHE A  69
 None
 1.35A 4mmfB-4gk9A:
undetectable		 4mmfB-4gk9A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		5 / 9 VAL A 148
ALA A 147
TYR A 146
GLY A 257
PHE A 269
 None
 1.34A 4mmfB-4gk9A:
undetectable		 4mmfB-4gk9A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		5 / 9 VAL A 214
ALA A 213
TYR A 212
GLY A 190
PHE A 202
 None
 1.34A 4mmfB-4gk9A:
undetectable		 4mmfB-4gk9A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		3 / 3 THR A 187
ASN A 205
SER A 206
 None
 0.66A 4tvtA-4gk9A:
undetectable		 4tvtA-4gk9A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		5 / 12 GLY A  29
GLY A  28
ASN A  16
ILE A 230
PHE A 136
 None
 1.18A 4zvmA-4gk9A:
undetectable
4zvmB-4gk9A:
undetectable		 4zvmA-4gk9A:
22.15
4zvmB-4gk9A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		3 / 3 TYR A  79
TYR A 128
GLN A 107
 None
 1.11A 5jsdA-4gk9A:
2.0
5jsdB-4gk9A:
undetectable		 5jsdA-4gk9A:
16.90
5jsdB-4gk9A:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 4gk9 AGGLUTININ (BOA)
(Burkholderia
oklahomensis) 		3 / 3 TYR A  79
TYR A 128
GLN A 107
 None
 1.11A 5jsdB-4gk9A:
undetectable
5jsdC-4gk9A:
undetectable		 5jsdB-4gk9A:
16.90
5jsdC-4gk9A:
16.90