SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gkf'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FBM_B_RTLB951_0 (PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN))	4gkf	CRISPR SYSTEM CMR SUBUNIT CMR5 (Pyrococcus furiosus)	4 / 4	THR A  74 LEU A  69 LEU A 128 GLN A 131	None	1.00A	1fbmA-4gkfA: undetectable	1fbmA-4gkfA: 15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G70_B_SAMB2002_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	4gkf	CRISPR SYSTEM CMR SUBUNIT CMR5 (Pyrococcus furiosus)	5 / 12	TYR A  45 LEU A  48 ALA A 156 PHE A 153 VAL A  33	None	1.43A	2g70B-4gkfA: undetectable	2g70B-4gkfA: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q6U_A_BEZA501_0 (NIKD PROTEIN)	4gkf	CRISPR SYSTEM CMR SUBUNIT CMR5 (Pyrococcus furiosus)	4 / 7	HIS A 110 PHE A  93 TYR A 113 TRP A 114	None	1.37A	2q6uA-4gkfA: undetectable	2q6uA-4gkfA: 17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWU_A_SREA801_1 (TRANSPORTER)	4gkf	CRISPR SYSTEM CMR SUBUNIT CMR5 (Pyrococcus furiosus)	5 / 12	LEU A 107 LEU A  68 TYR A  45 ALA A  72 ASP A 100	None	1.20A	3gwuA-4gkfA: undetectable	3gwuA-4gkfA: 14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IX9_A_MTXA200_1 (DIHYDROFOLATE REDUCTASE)	4gkf	CRISPR SYSTEM CMR SUBUNIT CMR5 (Pyrococcus furiosus)	6 / 12	ILE A 111 ALA A 139 GLN A  63 LEU A  69 VAL A 112 THR A 140	None	1.32A	3ix9A-4gkfA: undetectable	3ix9A-4gkfA: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IX9_A_MTXA200_1 (DIHYDROFOLATE REDUCTASE)	4gkf	CRISPR SYSTEM CMR SUBUNIT CMR5 (Pyrococcus furiosus)	5 / 12	ILE A 111 ALA A 139 LEU A  62 GLN A  63 VAL A 112	None	1.19A	3ix9A-4gkfA: undetectable	3ix9A-4gkfA: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZU_C_RTLC201_0 (RETINOL-BINDING PROTEIN 2)	4gkf	CRISPR SYSTEM CMR SUBUNIT CMR5 (Pyrococcus furiosus)	5 / 12	ILE A  30 ALA A  34 VAL A  86 LEU A  97 LEU A 106	None	1.19A	4qzuC-4gkfA: undetectable	4qzuC-4gkfA: 20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	4gkf	CRISPR SYSTEM CMR SUBUNIT CMR5 (Pyrococcus furiosus)	4 / 4	ASN A 148 LEU A 107 PHE A 153 TYR A  25	None	1.25A	4u14A-4gkfA: 0.3	4u14A-4gkfA: 16.56