SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gkp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		4 / 8 LEU A 425
ASP A 438
LEU A 439
LEU A 440
 None
 1.05A 1e7cA-4gkpA:
undetectable		 1e7cA-4gkpA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		5 / 12 ILE A 547
LEU A 526
SER A 529
LEU A 494
ILE A 492
 None
 1.20A 1fmlB-4gkpA:
undetectable		 1fmlB-4gkpA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		4 / 8 PHE A 514
PHE A 512
LEU A 378
VAL A 556
 None
 0.79A 1fslB-4gkpA:
undetectable		 1fslB-4gkpA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		4 / 5 TYR A 518
TYR A 483
ILE A 492
GLY A 398
 None
 1.27A 1kifA-4gkpA:
undetectable		 1kifA-4gkpA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		4 / 5 TYR A 518
TYR A 483
ILE A 492
GLY A 398
 None
 1.27A 1kifB-4gkpA:
undetectable		 1kifB-4gkpA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		4 / 5 TYR A 518
TYR A 483
ILE A 492
GLY A 398
 None
 1.27A 1kifC-4gkpA:
undetectable		 1kifC-4gkpA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		4 / 5 TYR A 518
TYR A 483
ILE A 492
GLY A 398
 None
 1.27A 1kifD-4gkpA:
undetectable		 1kifD-4gkpA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		4 / 5 TYR A 518
TYR A 483
ILE A 492
GLY A 398
 None
 1.27A 1kifE-4gkpA:
undetectable		 1kifE-4gkpA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		4 / 5 TYR A 518
TYR A 483
ILE A 492
GLY A 398
 None
 1.27A 1kifF-4gkpA:
undetectable		 1kifF-4gkpA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		4 / 5 TYR A 518
TYR A 483
ILE A 492
GLY A 398
 None
 1.27A 1kifG-4gkpA:
undetectable		 1kifG-4gkpA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		4 / 5 TYR A 518
TYR A 483
ILE A 492
GLY A 398
 None
 1.27A 1kifH-4gkpA:
undetectable		 1kifH-4gkpA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_D_DESD128_1
(TRANSTHYRETIN)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		4 / 4 LYS A 436
LEU A 430
LEU A 494
SER A 495
 None
 1.48A 1tz8D-4gkpA:
undetectable		 1tz8D-4gkpA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		4 / 5 TYR A 518
TYR A 483
ILE A 492
GLY A 398
 None
 1.28A 1ve9A-4gkpA:
undetectable		 1ve9A-4gkpA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		4 / 5 TYR A 518
TYR A 483
ILE A 492
GLY A 398
 None
 1.34A 2du8J-4gkpA:
undetectable		 2du8J-4gkpA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		5 / 11 PHE A 555
VAL A 397
PHE A 557
PHE A 548
LEU A 571
 None
 0.90A 3t3rA-4gkpA:
undetectable		 3t3rA-4gkpA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		5 / 10 ILE A 559
ASN A 342
TYR A 343
ILE A 330
GLU A 332
 None
 1.07A 3u6tA-4gkpA:
undetectable		 3u6tA-4gkpA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		4 / 5 ILE A 559
ASN A 342
TYR A 343
ILE A 330
 None
 0.94A 4jtpA-4gkpA:
undetectable		 4jtpA-4gkpA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		3 / 3 PHE A 557
THR A 551
LEU A 526
 None
 0.71A 4qztA-4gkpA:
1.4		 4qztA-4gkpA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		3 / 3 LYS A 436
LYS A 490
SER A 431
 None
 0.81A 5odiA-4gkpA:
undetectable		 5odiA-4gkpA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		3 / 3 PHE A 384
ASP A 383
LYS A 387
 None
 0.85A 6awtD-4gkpA:
undetectable		 6awtD-4gkpA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1
([Candida]
glabrata) 		5 / 12 LEU A 425
LEU A 544
VAL A 543
ILE A 461
ASP A 511
 None
 1.12A 6bxmA-4gkpA:
undetectable		 6bxmA-4gkpA:
22.94