SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gl3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 8 ASN A 190
GLN A 194
PHE A 192
TRP A 209
None
1.32A 1zzuA-4gl3A:
undetectable
1zzuA-4gl3A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 12 LEU A 159
ALA A 153
GLY A  80
SER A  82
LEU A  65
None
1.29A 2a58A-4gl3A:
undetectable
2a58B-4gl3A:
undetectable
2a58A-4gl3A:
16.47
2a58B-4gl3A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 12 LEU A 159
ALA A 153
GLY A  80
SER A  82
LEU A  65
None
1.29A 2a58B-4gl3A:
undetectable
2a58C-4gl3A:
undetectable
2a58B-4gl3A:
16.47
2a58C-4gl3A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 12 LEU A 159
ALA A 153
GLY A  80
SER A  82
LEU A  65
None
1.29A 2a58D-4gl3A:
undetectable
2a58E-4gl3A:
undetectable
2a58D-4gl3A:
16.47
2a58E-4gl3A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 5 PHE A 191
PHE A 192
TRP A 209
GLY A 146
None
0.83A 2qmzA-4gl3A:
undetectable
2qmzB-4gl3A:
undetectable
2qmzA-4gl3A:
18.31
2qmzB-4gl3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 6 PHE A 191
PHE A 192
TRP A 209
GLY A 146
None
0.87A 2qr2A-4gl3A:
undetectable
2qr2B-4gl3A:
undetectable
2qr2A-4gl3A:
18.31
2qr2B-4gl3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 6 PHE A 191
PHE A 192
TRP A 209
GLY A 146
None
0.96A 2qr2A-4gl3A:
undetectable
2qr2B-4gl3A:
undetectable
2qr2A-4gl3A:
18.31
2qr2B-4gl3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 5 TRP A 209
GLY A 146
PHE A 191
PHE A 192
None
0.83A 2qr2A-4gl3A:
undetectable
2qr2B-4gl3A:
undetectable
2qr2A-4gl3A:
18.31
2qr2B-4gl3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 5 TRP A 209
GLY A 146
PHE A 191
PHE A 192
None
0.97A 2qr2A-4gl3A:
undetectable
2qr2B-4gl3A:
undetectable
2qr2A-4gl3A:
18.31
2qr2B-4gl3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 8 PHE A 191
PHE A 192
TRP A 209
GLY A 146
None
0.88A 2qwxA-4gl3A:
undetectable
2qwxB-4gl3A:
undetectable
2qwxA-4gl3A:
18.31
2qwxB-4gl3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 7 TRP A 209
GLY A 146
PHE A 191
PHE A 192
None
0.97A 2qwxA-4gl3A:
undetectable
2qwxB-4gl3A:
undetectable
2qwxA-4gl3A:
18.31
2qwxB-4gl3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 8 PHE A 191
PHE A 192
TRP A 209
GLY A 146
None
0.88A 2qx4A-4gl3A:
undetectable
2qx4B-4gl3A:
undetectable
2qx4A-4gl3A:
18.31
2qx4B-4gl3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 6 TRP A 209
GLY A 146
PHE A 191
PHE A 192
None
0.91A 2qx6A-4gl3A:
undetectable
2qx6B-4gl3A:
undetectable
2qx6A-4gl3A:
18.31
2qx6B-4gl3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 8 VAL A 150
TYR A 337
PHE A 276
ASN A 219
None
PEG  A 504 ( 3.9A)
None
None
0.98A 2wekA-4gl3A:
undetectable
2wekA-4gl3A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 8 VAL A 150
TYR A 337
PHE A 276
ASN A 219
None
PEG  A 504 ( 3.9A)
None
None
0.99A 2wekB-4gl3A:
undetectable
2wekB-4gl3A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 8 GLY A  83
ILE A  90
MET A 282
ALA A  66
None
0.81A 2x0pA-4gl3A:
undetectable
2x0pA-4gl3A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A600_1
(ORF12)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 11 SER A  82
TYR A  54
ALA A  59
GLY A  64
SER A  63
None
1.32A 2xf3A-4gl3A:
undetectable
2xf3A-4gl3A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A600_1
(ORF12)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 10 SER A  82
TYR A  54
ALA A  59
GLY A  64
SER A  63
None
1.36A 2xfsA-4gl3A:
0.0
2xfsA-4gl3A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 12 PHE A 372
GLY A 327
LEU A 328
PHE A 390
ILE A 349
None
1.21A 2y7kD-4gl3A:
undetectable
2y7kD-4gl3A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 12 PHE A 154
GLU A 151
ALA A 330
PHE A 275
TYR A 279
None
TRS  A 500 (-3.3A)
TRS  A 500 ( 4.1A)
TRS  A 500 (-4.3A)
None
1.37A 3apwB-4gl3A:
undetectable
3apwB-4gl3A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 12 THR A 167
PHE A 166
GLU A 173
GLU A 101
TYR A 165
None
1.45A 3apxA-4gl3A:
undetectable
3apxA-4gl3A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 6 GLY A 265
TYR A 257
GLY A 272
ASN A 253
None
1.06A 3e9rA-4gl3A:
undetectable
3e9rA-4gl3A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 12 ASN A  71
SER A  70
PRO A 399
ILE A 404
GLU A 151
None
None
None
TRS  A 500 (-4.5A)
TRS  A 500 (-3.3A)
1.41A 3jb2A-4gl3A:
undetectable
3jb2A-4gl3A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3006_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 6 ASN A 131
MET A 130
ILE A 138
GLU A  75
None
1.27A 3kp6A-4gl3A:
undetectable
3kp6B-4gl3A:
undetectable
3kp6A-4gl3A:
17.00
3kp6B-4gl3A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 12 VAL A 348
THR A 352
ILE A 409
LEU A 380
TYR A 279
None
1.20A 3sp9B-4gl3A:
undetectable
3sp9B-4gl3A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 11 GLY A 333
ASP A 334
TYR A 318
ASP A 345
TYR A 321
None
1.29A 3wqvA-4gl3A:
undetectable
3wqvA-4gl3A:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 11 GLY A 333
ASP A 334
TYR A 318
ASP A 345
TYR A 321
None
1.31A 3wqwA-4gl3A:
undetectable
3wqwA-4gl3A:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 7 LEU A 402
GLY A 336
TYR A 337
SER A 338
None
None
PEG  A 504 ( 3.9A)
None
1.00A 4cp3A-4gl3A:
undetectable
4cp3B-4gl3A:
undetectable
4cp3A-4gl3A:
14.59
4cp3B-4gl3A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 8 PHE A 191
PHE A 192
TRP A 209
GLY A 146
None
0.87A 4fgjA-4gl3A:
undetectable
4fgjB-4gl3A:
undetectable
4fgjA-4gl3A:
18.55
4fgjB-4gl3A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 12 VAL A 431
ALA A 153
LEU A 159
LEU A 160
MET A 125
None
1.19A 4i1rA-4gl3A:
undetectable
4i1rA-4gl3A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 8 GLY A  85
GLY A  80
ILE A 404
GLU A 220
None
None
TRS  A 500 (-4.5A)
TRS  A 500 (-4.1A)
0.81A 4mwzB-4gl3A:
undetectable
4mwzB-4gl3A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 12 ALA A 339
THR A 250
ASN A 219
GLY A 271
LEU A 262
None
1.10A 4n48B-4gl3A:
undetectable
4n48B-4gl3A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
3 / 3 MET A 412
MET A 155
TYR A 281
None
1.32A 4p6xI-4gl3A:
undetectable
4p6xI-4gl3A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 8 PHE A 191
PHE A 192
TRP A 209
GLY A 146
None
0.81A 4qogA-4gl3A:
undetectable
4qogB-4gl3A:
undetectable
4qogA-4gl3A:
18.31
4qogB-4gl3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 8 PHE A 191
PHE A 192
TRP A 209
GLY A 146
None
0.86A 4qoiA-4gl3A:
undetectable
4qoiB-4gl3A:
undetectable
4qoiA-4gl3A:
18.31
4qoiB-4gl3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 9 THR A  78
ALA A  66
ALA A  59
GLY A  80
GLY A  83
None
1.08A 4qwuK-4gl3A:
undetectable
4qwuL-4gl3A:
undetectable
4qwuK-4gl3A:
19.58
4qwuL-4gl3A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 9 THR A  78
ALA A  66
ALA A  59
GLY A  80
GLY A  83
None
1.03A 4qwuY-4gl3A:
undetectable
4qwuZ-4gl3A:
undetectable
4qwuY-4gl3A:
19.58
4qwuZ-4gl3A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 12 ALA A 403
GLY A 407
ILE A 223
ALA A 153
PHE A  84
None
1.10A 4r29D-4gl3A:
undetectable
4r29D-4gl3A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
4 / 7 LEU A 402
SER A 400
GLY A 333
ALA A 398
None
0.61A 4yjiA-4gl3A:
undetectable
4yjiA-4gl3A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 12 GLY A 158
SER A  82
ILE A  90
VAL A 411
VAL A  91
None
1.12A 5dpdB-4gl3A:
undetectable
5dpdB-4gl3A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 12 PHE A  55
PHE A 154
ILE A 223
PHE A  84
THR A  78
None
1.30A 5vcgA-4gl3A:
undetectable
5vcgA-4gl3A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_0
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)
4gl3 PUTATIVE
GLUCOAMYLASE

(Bacteroides
uniformis)
5 / 12 TYR A 360
HIS A 303
TRP A 245
HIS A 218
PHE A 276
None
1.39A 6hloA-4gl3A:
0.3
6hloA-4gl3A:
20.74