SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gl6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 4gl6 HYPOTHETICAL PROTEIN
([Ruminococcus]
gnavus) 		5 / 10 TYR A 203
ILE A 169
TYR A 186
ILE A 115
ILE A 124
 None
None
None
None
GOL  A 301 ( 4.0A)
 1.19A 3p4wD-4gl6A:
undetectable		 3p4wD-4gl6A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 4gl6 HYPOTHETICAL PROTEIN
([Ruminococcus]
gnavus) 		5 / 10 TYR A 203
ILE A 169
TYR A 186
ILE A 115
ILE A 124
 None
None
None
None
GOL  A 301 ( 4.0A)
 1.19A 3p4wE-4gl6A:
undetectable		 3p4wE-4gl6A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 4gl6 HYPOTHETICAL PROTEIN
([Ruminococcus]
gnavus) 		4 / 6 TYR A  98
TYR A  36
GLY A  42
GLU A  43
 None
 1.17A 5emlA-4gl6A:
undetectable		 5emlA-4gl6A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 4gl6 HYPOTHETICAL PROTEIN
([Ruminococcus]
gnavus) 		3 / 3 ILE A 128
ILE A 142
MET A 107
 None
 0.64A 5i9yA-4gl6A:
undetectable		 5i9yA-4gl6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_C_RIOC600_0
(BIFUNCTIONAL AAC/APH)		 4gl6 HYPOTHETICAL PROTEIN
([Ruminococcus]
gnavus) 		5 / 12 SER A 222
GLU A 230
GLU A 225
VAL A 202
TYR A 238
 None
 1.43A 5iqdC-4gl6A:
4.2		 5iqdC-4gl6A:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)		 4gl6 HYPOTHETICAL PROTEIN
([Ruminococcus]
gnavus) 		4 / 7 GLY A 240
ILE A 256
GLN A 262
TYR A 183
 None
 0.97A 5vlmC-4gl6A:
undetectable		 5vlmC-4gl6A:
21.37