SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4glp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 4glp MONOCYTE
DIFFERENTIATION
ANTIGEN CD14
(Homo
sapiens) 		3 / 3 GLN A 225
HIS A 252
PRO A 251
 None
 0.95A 1d8cA-4glpA:
undetectable		 1d8cA-4glpA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 4glp MONOCYTE
DIFFERENTIATION
ANTIGEN CD14
(Homo
sapiens) 		5 / 12 LEU A 227
LEU A 199
LEU A 175
LEU A 212
LEU A 207
 None
 1.04A 1sqnB-4glpA:
undetectable		 1sqnB-4glpA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 4glp MONOCYTE
DIFFERENTIATION
ANTIGEN CD14
(Homo
sapiens) 		4 / 7 HIS A  60
ALA A  98
GLY A  63
GLY A  62
 None
 0.73A 2c49B-4glpA:
undetectable		 2c49B-4glpA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 4glp MONOCYTE
DIFFERENTIATION
ANTIGEN CD14
(Homo
sapiens) 		3 / 3 ARG A 148
THR A 197
VAL A 174
 None
 0.86A 2q64A-4glpA:
undetectable		 2q64A-4glpA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 4glp MONOCYTE
DIFFERENTIATION
ANTIGEN CD14
(Homo
sapiens) 		3 / 3 ARG A 148
THR A 197
VAL A 174
 None
 0.85A 2qakA-4glpA:
undetectable		 2qakA-4glpA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 4glp MONOCYTE
DIFFERENTIATION
ANTIGEN CD14
(Homo
sapiens) 		5 / 12 LEU A 144
LEU A 147
LEU A 126
VAL A 152
VAL A 107
 None
 1.33A 2qd4A-4glpA:
undetectable		 2qd4A-4glpA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 4glp MONOCYTE
DIFFERENTIATION
ANTIGEN CD14
(Homo
sapiens) 		3 / 3 TRP A 154
ALA A 180
VAL A 152
 None
 1.02A 3l8lA-4glpA:
undetectable
3l8lB-4glpA:
undetectable		 3l8lA-4glpA:
7.10
3l8lB-4glpA:
6.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4glp MONOCYTE
DIFFERENTIATION
ANTIGEN CD14
(Homo
sapiens) 		4 / 7 PRO A 205
ARG A 230
ALA A 178
ARG A 150
 None
 1.10A 3twpC-4glpA:
undetectable		 3twpC-4glpA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4glp MONOCYTE
DIFFERENTIATION
ANTIGEN CD14
(Homo
sapiens) 		4 / 7 TRP A  45
GLY A  62
GLY A  63
ASN A  65
 None
 1.12A 4fgkB-4glpA:
undetectable		 4fgkB-4glpA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 4glp MONOCYTE
DIFFERENTIATION
ANTIGEN CD14
(Homo
sapiens) 		4 / 5 LEU A 164
LEU A 172
THR A 122
ARG A 117
 None
 1.06A 6ew0F-4glpA:
undetectable		 6ew0F-4glpA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 4glp MONOCYTE
DIFFERENTIATION
ANTIGEN CD14
(Homo
sapiens) 		4 / 6 LEU A 164
LEU A 172
THR A 122
ARG A 117
 None
 1.06A 6ew0G-4glpA:
undetectable		 6ew0G-4glpA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 4glp MONOCYTE
DIFFERENTIATION
ANTIGEN CD14
(Homo
sapiens) 		4 / 7 ILE A 128
LEU A 106
LEU A 123
LEU A 168
 None
 0.68A 6g9bA-4glpA:
undetectable
6g9bB-4glpA:
undetectable		 6g9bA-4glpA:
13.09
6g9bB-4glpA:
12.30