SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gm6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 LEU A 172
GLY A  33
GLY A  34
ASN A  38
ASP A 270
 None
GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 (-3.0A)
 0.83A 1bx4A-4gm6A:
28.9		 1bx4A-4gm6A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 9 ALA A  40
GLY A  33
ILE A  32
VAL A  79
ILE A  52
 None
GOL  A 401 ( 4.1A)
None
None
None
 1.03A 1hpvB-4gm6A:
undetectable		 1hpvB-4gm6A:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 ALA A  40
GLY A  33
ILE A  32
VAL A  79
ILE A  52
 None
GOL  A 401 ( 4.1A)
None
None
None
 0.97A 1hxbB-4gm6A:
undetectable		 1hxbB-4gm6A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 LEU A 172
GLY A  33
GLY A  34
ASN A  38
ASP A 270
 None
GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 (-3.0A)
 0.85A 1liiA-4gm6A:
25.8		 1liiA-4gm6A:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 LEU A 172
GLY A  33
GLY A  34
ASN A  38
ASP A 270
 None
GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 (-3.0A)
 0.93A 1likA-4gm6A:
28.2		 1likA-4gm6A:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 11 ALA A  40
GLY A  33
ILE A  32
VAL A  79
ILE A  52
 None
GOL  A 401 ( 4.1A)
None
None
None
 0.94A 1t3rB-4gm6A:
undetectable		 1t3rB-4gm6A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_A_ADNA901_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 10 PHE A 164
HIS A 132
ILE A 138
ALA A  35
TYR A 182
 None
None
None
GOL  A 401 (-3.9A)
None
 1.40A 2gl0A-4gm6A:
undetectable
2gl0B-4gm6A:
undetectable		 2gl0A-4gm6A:
19.05
2gl0B-4gm6A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_B_ADNB902_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 11 PHE A 164
HIS A 132
ILE A 138
ALA A  35
TYR A 182
 None
None
None
GOL  A 401 (-3.9A)
None
 1.37A 2gl0B-4gm6A:
undetectable
2gl0C-4gm6A:
undetectable		 2gl0B-4gm6A:
19.05
2gl0C-4gm6A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 ILE A 138
ALA A  35
TYR A 182
PHE A 164
HIS A 132
 None
GOL  A 401 (-3.9A)
None
None
None
 1.45A 2gl0A-4gm6A:
undetectable
2gl0C-4gm6A:
undetectable		 2gl0A-4gm6A:
19.05
2gl0C-4gm6A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 PHE A 164
HIS A 132
ILE A 138
ALA A  35
TYR A 182
 None
None
None
GOL  A 401 (-3.9A)
None
 1.38A 2gl0D-4gm6A:
undetectable
2gl0E-4gm6A:
undetectable		 2gl0D-4gm6A:
19.05
2gl0E-4gm6A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_E_ADNE905_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 11 PHE A 164
HIS A 132
ILE A 138
ALA A  35
TYR A 182
 None
None
None
GOL  A 401 (-3.9A)
None
 1.40A 2gl0E-4gm6A:
undetectable
2gl0F-4gm6A:
undetectable		 2gl0E-4gm6A:
19.05
2gl0F-4gm6A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_F_ADNF906_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 11 ILE A 138
ALA A  35
TYR A 182
PHE A 164
HIS A 132
 None
GOL  A 401 (-3.9A)
None
None
None
 1.42A 2gl0D-4gm6A:
undetectable
2gl0F-4gm6A:
undetectable		 2gl0D-4gm6A:
19.05
2gl0F-4gm6A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_B_017B203_1
(HIV-1 PROTEASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		4 / 7 GLU A 253
TRP A 252
LYS A 291
GLY A 243
 None
 1.09A 2hs1B-4gm6A:
undetectable		 2hs1B-4gm6A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 9 ALA A  40
GLY A  33
ILE A  32
VAL A  79
ILE A  52
 None
GOL  A 401 ( 4.1A)
None
None
None
 1.01A 2o4pB-4gm6A:
undetectable		 2o4pB-4gm6A:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLY A 267
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.30A 2pkkA-4gm6A:
25.9		 2pkkA-4gm6A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLY A 267
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.31A 2pkmA-4gm6A:
25.7		 2pkmA-4gm6A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		4 / 7 ALA A 228
TYR A 272
TYR A 227
TYR A 213
 None
 1.35A 2pncA-4gm6A:
undetectable		 2pncA-4gm6A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		4 / 8 TYR A 257
ARG A 265
ILE A 259
SER A 254
 None
 1.13A 2xytH-4gm6A:
undetectable		 2xytH-4gm6A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		4 / 8 MET A  64
ALA A  65
GLY A  62
ILE A  61
 None
 0.73A 2zm9A-4gm6A:
undetectable		 2zm9A-4gm6A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 9 ALA A  40
GLY A  33
ILE A  32
VAL A  79
ILE A  52
 None
GOL  A 401 ( 4.1A)
None
None
None
 0.91A 3ekvB-4gm6A:
undetectable		 3ekvB-4gm6A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 ASN A 167
ALA A  35
VAL A   4
LEU A 277
THR A 273
 None
GOL  A 401 (-3.9A)
None
None
None
 1.22A 3hkuA-4gm6A:
undetectable		 3hkuA-4gm6A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 11 ALA A  53
VAL A  55
ILE A   7
GLY A   8
THR A 137
 None
 1.10A 3kw2A-4gm6A:
undetectable		 3kw2A-4gm6A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 11 ALA A  53
VAL A  55
ILE A   7
GLY A   8
THR A 137
 None
 1.12A 3kw2B-4gm6A:
2.4		 3kw2B-4gm6A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 11 ALA A  40
GLY A  33
ILE A  32
VAL A  79
ILE A  52
 None
GOL  A 401 ( 4.1A)
None
None
None
 1.01A 3lzvB-4gm6A:
undetectable		 3lzvB-4gm6A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 9 ALA A  40
GLY A  33
ILE A  32
VAL A  79
ILE A  52
 None
GOL  A 401 ( 4.1A)
None
None
None
 1.08A 3nu4A-4gm6A:
undetectable		 3nu4A-4gm6A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_1
(PROTEASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 9 ALA A  40
GLY A  33
ILE A  32
VAL A  79
ILE A  52
 None
GOL  A 401 ( 4.1A)
None
None
None
 1.06A 3nuoA-4gm6A:
undetectable		 3nuoA-4gm6A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
GLY A 267
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.67A 3uboA-4gm6A:
30.1		 3uboA-4gm6A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 0.99A 3uboB-4gm6A:
30.8		 3uboB-4gm6A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLY A 267
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.41A 3uq6A-4gm6A:
25.2		 3uq6A-4gm6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 LEU A 172
GLY A  33
GLY A  34
ASN A  38
ASP A 270
 None
GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 (-3.0A)
 0.85A 3uq6A-4gm6A:
25.2		 3uq6A-4gm6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 ALA A  35
ASN A  38
LEU A 140
GLY A 267
ASP A 270
 GOL  A 401 (-3.9A)
GOL  A 401 (-4.4A)
None
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.87A 3uq6B-4gm6A:
28.1		 3uq6B-4gm6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 ALA A  35
ASN A  38
LEU A 172
GLY A 267
ASP A 270
 GOL  A 401 (-3.9A)
GOL  A 401 (-4.4A)
None
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 1.11A 3uq6B-4gm6A:
28.1		 3uq6B-4gm6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  34
ALA A  35
ASN A  38
GLY A 267
ASP A 270
 GOL  A 401 (-3.7A)
GOL  A 401 (-3.9A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.37A 3uq6B-4gm6A:
28.1		 3uq6B-4gm6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 LEU A 172
ASN A  38
LEU A 140
GLY A 267
ASP A 270
 None
GOL  A 401 (-4.4A)
None
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 1.10A 3uq6B-4gm6A:
28.1		 3uq6B-4gm6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 LEU A 172
GLY A  34
ASN A  38
GLY A 267
ASP A 270
 None
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.84A 3uq6B-4gm6A:
28.1		 3uq6B-4gm6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 LEU A 172
GLY A  33
GLY A  34
ASN A  38
GLY A 267
ASP A 270
 None
GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.80A 3vaqA-4gm6A:
29.3		 3vaqA-4gm6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 LEU A 172
ALA A  35
ASN A  38
LEU A 140
GLY A 267
ASP A 270
 None
GOL  A 401 (-3.9A)
GOL  A 401 (-4.4A)
None
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 1.02A 3vaqB-4gm6A:
28.1		 3vaqB-4gm6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 LEU A 172
GLY A  34
ALA A  35
ASN A  38
GLY A 267
ASP A 270
 None
GOL  A 401 (-3.7A)
GOL  A 401 (-3.9A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.82A 3vaqB-4gm6A:
28.1		 3vaqB-4gm6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 LEU A 172
GLY A  33
GLY A  34
ASN A  38
GLY A 267
ASP A 270
 None
GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.79A 3vasA-4gm6A:
29.2		 3vasA-4gm6A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 LEU A 172
ASN A  38
LEU A 140
GLY A 267
ASP A 270
 None
GOL  A 401 (-4.4A)
None
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 1.05A 3vasB-4gm6A:
20.6		 3vasB-4gm6A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 LEU A 172
GLY A  33
GLY A  34
ASN A  38
GLY A 267
ASP A 270
 None
GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.76A 3vasB-4gm6A:
20.6		 3vasB-4gm6A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 11 ILE A 162
ILE A 160
GLY A 159
VAL A   4
SER A 282
 None
 1.05A 4ac9B-4gm6A:
3.8
4ac9C-4gm6A:
4.8		 4ac9B-4gm6A:
24.13
4ac9C-4gm6A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 LEU A 172
ALA A  35
ASN A  38
LEU A 140
GLY A 267
ASP A 270
 None
GOL  A 401 (-3.9A)
GOL  A 401 (-4.4A)
None
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 1.08A 4dc3A-4gm6A:
27.6		 4dc3A-4gm6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 LEU A 172
GLY A  33
ALA A  35
ASN A  38
GLY A 267
ASP A 270
 None
GOL  A 401 ( 4.1A)
GOL  A 401 (-3.9A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.91A 4dc3A-4gm6A:
27.6		 4dc3A-4gm6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 LEU A 140
GLY A  33
GLY A  34
ASN A  38
GLY A 267
ASP A 270
 None
GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 1.35A 4dc3B-4gm6A:
25.1		 4dc3B-4gm6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 LEU A 172
GLY A  33
GLY A  34
ASN A  38
GLY A 267
ASP A 270
 None
GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.79A 4dc3B-4gm6A:
25.1		 4dc3B-4gm6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 LEU A 172
GLY A  34
ASN A  38
LEU A 140
GLY A 267
ASP A 270
 None
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 1.10A 4dc3B-4gm6A:
25.1		 4dc3B-4gm6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 10 ALA A  40
GLY A  33
ILE A  32
VAL A  79
ILE A  52
 None
GOL  A 401 ( 4.1A)
None
None
None
 0.98A 4dqcA-4gm6A:
undetectable		 4dqcA-4gm6A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 11 ALA A  40
GLY A  33
ILE A  32
VAL A  79
ILE A  52
 None
GOL  A 401 ( 4.1A)
None
None
None
 0.95A 4dqeA-4gm6A:
undetectable		 4dqeA-4gm6A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 11 ALA A  40
GLY A  33
ILE A  32
VAL A  79
ILE A  52
 None
GOL  A 401 ( 4.1A)
None
None
None
 0.92A 4dqhA-4gm6A:
undetectable		 4dqhA-4gm6A:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 11 SER A 109
VAL A  56
LEU A  86
ALA A  65
VAL A  79
 None
 1.14A 4e0fA-4gm6A:
undetectable		 4e0fA-4gm6A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 1.00A 4e3aA-4gm6A:
31.2		 4e3aA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		7 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
GLY A 267
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.92A 4e3aB-4gm6A:
31.5		 4e3aB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.63A 4jksA-4gm6A:
31.1		 4jksA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.62A 4jksB-4gm6A:
31.1		 4jksB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.62A 4jkuA-4gm6A:
31.0		 4jkuA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 0.99A 4jkuB-4gm6A:
31.1		 4jkuB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.63A 4k8cA-4gm6A:
31.0		 4k8cA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.62A 4k8cB-4gm6A:
31.2		 4k8cB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.63A 4k8kA-4gm6A:
31.1		 4k8kA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.62A 4k8kB-4gm6A:
31.2		 4k8kB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 0.99A 4k8pA-4gm6A:
31.1		 4k8pA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 0.99A 4k8pB-4gm6A:
31.1		 4k8pB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 0.98A 4k8tA-4gm6A:
31.0		 4k8tA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 1.01A 4k8tB-4gm6A:
31.0		 4k8tB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 0.99A 4k93A-4gm6A:
31.1		 4k93A-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 0.99A 4k93B-4gm6A:
31.1		 4k93B-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 1.00A 4k9cA-4gm6A:
31.1		 4k9cA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 0.98A 4k9cB-4gm6A:
31.1		 4k9cB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 1.00A 4k9iA-4gm6A:
31.0		 4k9iA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 1.00A 4k9iB-4gm6A:
31.0		 4k9iB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 1.00A 4kadA-4gm6A:
31.1		 4kadA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 1.00A 4kadB-4gm6A:
28.6		 4kadB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.62A 4kahA-4gm6A:
31.1		 4kahA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.62A 4kahB-4gm6A:
31.1		 4kahB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.61A 4kalA-4gm6A:
31.0		 4kalA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.63A 4kalB-4gm6A:
31.0		 4kalB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.63A 4kanA-4gm6A:
31.0		 4kanA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.63A 4kanB-4gm6A:
31.1		 4kanB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.63A 4kbeA-4gm6A:
31.1		 4kbeA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.63A 4kbeB-4gm6A:
31.0		 4kbeB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.62A 4lbgA-4gm6A:
31.1		 4lbgA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.63A 4lbgB-4gm6A:
31.1		 4lbgB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 1.01A 4lbxA-4gm6A:
31.0		 4lbxA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 1.01A 4lbxB-4gm6A:
31.1		 4lbxB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 1.00A 4lc4A-4gm6A:
31.1		 4lc4A-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 140
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
None
GOL  A 401 (-3.0A)
 1.00A 4lc4B-4gm6A:
31.1		 4lc4B-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.63A 4lcaA-4gm6A:
31.1		 4lcaA-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 (-3.0A)
 0.61A 4lcaB-4gm6A:
31.1		 4lcaB-4gm6A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 LEU A 172
GLY A  34
ASN A  38
GLY A 267
ASP A 270
 None
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.95A 4n09A-4gm6A:
29.2		 4n09A-4gm6A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 LEU A 172
GLY A  33
GLY A  34
ASN A  38
GLY A 267
ASP A 270
 None
GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.96A 4n09B-4gm6A:
29.2		 4n09B-4gm6A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 LEU A 172
GLY A  33
GLY A  34
ASN A  38
GLY A 267
ASP A 270
 None
GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.95A 4n09C-4gm6A:
29.2		 4n09C-4gm6A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 LEU A 172
GLY A  34
ASN A  38
LEU A 140
GLY A 267
ASP A 270
 None
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
None
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 1.14A 4n09C-4gm6A:
29.2		 4n09C-4gm6A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		6 / 12 LEU A 172
GLY A  33
GLY A  34
ASN A  38
GLY A 267
ASP A 270
 None
GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.98A 4n09D-4gm6A:
29.3		 4n09D-4gm6A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 10 ALA A  40
GLY A  33
ILE A  32
VAL A  79
ILE A  52
 None
GOL  A 401 ( 4.1A)
None
None
None
 0.94A 4q1wB-4gm6A:
undetectable		 4q1wB-4gm6A:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		3 / 3 TYR A 191
ARG A 129
LYS A 161
 None
 1.47A 4wq5B-4gm6A:
1.4		 4wq5B-4gm6A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		4 / 5 ILE A   7
VAL A 148
ILE A 152
VAL A 133
 None
 0.72A 4xdtA-4gm6A:
undetectable		 4xdtA-4gm6A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 LEU A 172
LEU A  11
TYR A  89
GLY A   8
SER A 134
 None
 1.39A 4zbrA-4gm6A:
undetectable		 4zbrA-4gm6A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJQ_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 SER A 254
THR A 294
ILE A 223
PHE A 203
GLU A 253
 None
 1.50A 4zjqD-4gm6A:
undetectable		 4zjqD-4gm6A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLY A 267
ASP A 270
 GOL  A 401 ( 4.1A)
GOL  A 401 (-3.7A)
GOL  A 401 (-4.4A)
GOL  A 401 ( 4.5A)
GOL  A 401 (-3.0A)
 0.40A 5kb5A-4gm6A:
28.9		 5kb5A-4gm6A:
25.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_1
(PROTEASE E35D-APV)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 9 ALA A  40
GLY A  33
ILE A  32
VAL A  79
ILE A  52
 None
GOL  A 401 ( 4.1A)
None
None
None
 0.94A 5kr0A-4gm6A:
undetectable		 5kr0A-4gm6A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 12 ALA A  35
GLY A   8
ASP A 264
GLY A 305
LEU A  91
 GOL  A 401 (-3.9A)
None
None
None
None
 1.01A 5wwsA-4gm6A:
3.2		 5wwsA-4gm6A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 4gm6 PFKB FAMILY
CARBOHYDRATE KINASE
(Listeria
grayi) 		5 / 10 ALA A  40
GLY A  33
ILE A  32
VAL A  79
ILE A  52
 None
GOL  A 401 ( 4.1A)
None
None
None
 1.01A 6dj2A-4gm6A:
undetectable		 6dj2A-4gm6A:
14.42