SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gmk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 12 ASP A  87
ALA A  86
GLY A 204
GLY A  98
LEU A 205
 PO4  A 301 (-2.6A)
None
None
PO4  A 301 (-4.0A)
None
 1.04A 1rjdA-4gmkA:
undetectable		 1rjdA-4gmkA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 12 ASP A  87
ALA A  86
GLY A 204
GLY A  98
LEU A 205
 PO4  A 301 (-2.6A)
None
None
PO4  A 301 (-4.0A)
None
 1.04A 1rjdB-4gmkA:
2.7		 1rjdB-4gmkA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 12 ASP A  87
ALA A  86
GLY A 204
GLY A  98
LEU A 205
 PO4  A 301 (-2.6A)
None
None
PO4  A 301 (-4.0A)
None
 1.05A 1rjdC-4gmkA:
undetectable		 1rjdC-4gmkA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 7 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.72A 1usqA-4gmkA:
undetectable		 1usqA-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 6 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.71A 1usqB-4gmkA:
undetectable		 1usqB-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 6 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.72A 1usqC-4gmkA:
undetectable		 1usqC-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 6 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.71A 1usqD-4gmkA:
undetectable		 1usqD-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 6 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.72A 1usqE-4gmkA:
undetectable		 1usqE-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 7 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.73A 1usqF-4gmkA:
undetectable		 1usqF-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 10 GLY A 100
ALA A 101
GLY A 204
ILE A  96
ILE A 176
 PO4  A 301 (-3.6A)
None
None
None
None
 0.93A 2aquA-4gmkA:
undetectable		 2aquA-4gmkA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 6 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.64A 2jkjA-4gmkA:
undetectable		 2jkjA-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 6 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.64A 2jkjB-4gmkA:
undetectable		 2jkjB-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 6 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.64A 2jkjC-4gmkA:
undetectable		 2jkjC-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 7 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.65A 2jkjE-4gmkA:
undetectable		 2jkjE-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 7 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.67A 2jklA-4gmkA:
undetectable		 2jklA-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 6 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.63A 2jklB-4gmkA:
undetectable		 2jklB-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 7 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.65A 2jklC-4gmkA:
undetectable		 2jklC-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 7 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.66A 2jklD-4gmkA:
undetectable		 2jklD-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 7 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.65A 2jklE-4gmkA:
undetectable		 2jklE-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 7 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.66A 2jklF-4gmkA:
undetectable		 2jklF-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 12 GLY A  85
ALA A  86
ASP A  87
ILE A 209
ILE A  89
 PO4  A 301 (-3.8A)
None
PO4  A 301 (-2.6A)
None
None
 1.04A 2qhcB-4gmkA:
undetectable		 2qhcB-4gmkA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 12 GLY A 100
ALA A 101
GLY A 204
ILE A  96
ILE A 176
 PO4  A 301 (-3.6A)
None
None
None
None
 0.91A 2rkfA-4gmkA:
undetectable		 2rkfA-4gmkA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 10 GLU A  16
ILE A 214
GLY A  11
ILE A  83
MET A 117
 None
 1.35A 3adsA-4gmkA:
undetectable		 3adsA-4gmkA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 8 VAL A  51
ASP A  80
GLY A  25
HIS A  78
 None
 1.01A 3af0A-4gmkA:
undetectable		 3af0A-4gmkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 12 GLN A  62
VAL A  32
LEU A  26
THR A  55
THR A  54
 None
 1.29A 3bl1A-4gmkA:
undetectable		 3bl1A-4gmkA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		3 / 3 SER A  56
GLY A  27
GLY A  29
 None
None
PO4  A 302 ( 3.8A)
 0.49A 3bogA-4gmkA:
undetectable
3bogC-4gmkA:
undetectable		 3bogA-4gmkA:
undetectable
3bogC-4gmkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 11 GLY A 100
ALA A 101
GLY A 204
ILE A  96
ILE A 176
 PO4  A 301 (-3.6A)
None
None
None
None
 1.04A 3ektD-4gmkA:
undetectable		 3ektD-4gmkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 12 GLY A 144
VAL A 198
GLY A 199
ILE A 139
ILE A 177
 None
 0.79A 3ekwB-4gmkA:
undetectable		 3ekwB-4gmkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 10 GLY A 100
ALA A 101
GLY A 204
ILE A  96
ILE A 176
 PO4  A 301 (-3.6A)
None
None
None
None
 0.98A 3ekyA-4gmkA:
undetectable		 3ekyA-4gmkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 11 GLY A 100
ALA A 101
GLY A 204
ILE A  96
ILE A 176
 PO4  A 301 (-3.6A)
None
None
None
None
 0.99A 3el1A-4gmkA:
undetectable		 3el1A-4gmkA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 12 GLY A 100
ALA A 101
GLY A 204
ILE A  96
ILE A 176
 PO4  A 301 (-3.6A)
None
None
None
None
 0.99A 3lzsB-4gmkA:
undetectable		 3lzsB-4gmkA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 12 GLY A 100
ALA A 101
GLY A 204
ILE A  96
ILE A 176
 PO4  A 301 (-3.6A)
None
None
None
None
 0.96A 3lzuA-4gmkA:
undetectable		 3lzuA-4gmkA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 11 GLN A  62
VAL A  32
LEU A  26
THR A  55
THR A  54
 None
 1.24A 3ml5A-4gmkA:
undetectable		 3ml5A-4gmkA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 12 GLY A 100
ALA A 101
GLY A 204
ILE A  96
ILE A 176
 PO4  A 301 (-3.6A)
None
None
None
None
 0.85A 3ndwA-4gmkA:
undetectable		 3ndwA-4gmkA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 12 ILE A  89
ASP A 178
ILE A 176
ASP A  87
PHE A 132
 None
None
None
PO4  A 301 (-2.6A)
None
 1.44A 3phaB-4gmkA:
undetectable		 3phaB-4gmkA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 12 GLY A 100
ALA A 101
GLY A 204
ILE A  96
ILE A 176
 PO4  A 301 (-3.6A)
None
None
None
None
 0.99A 3tkwA-4gmkA:
undetectable		 3tkwA-4gmkA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 7 VAL A 210
GLY A  95
ILE A  96
VAL A 120
 None
 0.84A 3ufnB-4gmkA:
undetectable		 3ufnB-4gmkA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 11 GLN A  62
VAL A  32
LEU A  26
THR A  55
THR A  54
 None
 1.31A 3v2jA-4gmkA:
undetectable		 3v2jA-4gmkA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 12 ALA A  86
ASP A 178
ILE A 176
ASP A  87
PHE A 132
 None
None
None
PO4  A 301 (-2.6A)
None
 1.50A 3welA-4gmkA:
undetectable		 3welA-4gmkA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1224_0
(THAUMATIN-LIKE
PROTEIN)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 5 SER A  56
GLU A 106
THR A  59
ASP A  84
 None
PO4  A 301 (-3.1A)
None
PO4  A 301 ( 4.3A)
 1.21A 3zs3A-4gmkA:
undetectable		 3zs3A-4gmkA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 11 GLY A 100
ALA A 101
GLY A 204
ILE A  96
ILE A 176
 PO4  A 301 (-3.6A)
None
None
None
None
 1.00A 4hlaB-4gmkA:
undetectable		 4hlaB-4gmkA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 11 GLN A  62
VAL A  32
LEU A  26
THR A  55
THR A  54
 None
 1.27A 4k0sA-4gmkA:
undetectable		 4k0sA-4gmkA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_1
(PROTEASE)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 12 GLY A 100
ALA A 101
GLY A 204
ILE A  96
ILE A 176
 PO4  A 301 (-3.6A)
None
None
None
None
 1.05A 4njvA-4gmkA:
undetectable		 4njvA-4gmkA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 11 GLN A  62
VAL A  32
LEU A  26
THR A  55
THR A  54
 None
 1.25A 4uovC-4gmkA:
undetectable		 4uovC-4gmkA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		3 / 3 ASP A 178
LEU A 103
GLY A  98
 None
None
PO4  A 301 (-4.0A)
 0.55A 4xmfA-4gmkA:
undetectable		 4xmfA-4gmkA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 10 GLN A  62
VAL A  32
LEU A  26
THR A  55
THR A  54
 None
 1.23A 5jn8A-4gmkA:
undetectable		 5jn8A-4gmkA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 11 GLN A  62
VAL A  32
LEU A  26
THR A  55
THR A  54
 None
 1.25A 5jn8B-4gmkA:
undetectable		 5jn8B-4gmkA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 10 GLN A  62
VAL A  32
LEU A  26
THR A  55
THR A  54
 None
 1.24A 5jn9A-4gmkA:
undetectable		 5jn9A-4gmkA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 10 GLN A  62
VAL A  32
LEU A  26
THR A  55
THR A  54
 None
 1.28A 5jn9B-4gmkA:
undetectable		 5jn9B-4gmkA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 10 GLN A  62
VAL A  32
LEU A  26
THR A  55
THR A  54
 None
 1.24A 5jn9D-4gmkA:
undetectable		 5jn9D-4gmkA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 12 GLN A  62
VAL A  32
LEU A  26
THR A  55
THR A  54
 None
 1.35A 5jnaB-4gmkA:
undetectable		 5jnaB-4gmkA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 12 GLN A  62
VAL A  32
LEU A  26
THR A  55
THR A  54
 None
 1.31A 5jnaD-4gmkA:
undetectable		 5jnaD-4gmkA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 11 GLN A  62
VAL A  32
LEU A  26
THR A  55
THR A  54
 None
 1.24A 5jncA-4gmkA:
undetectable		 5jncA-4gmkA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 10 GLN A  62
VAL A  32
LEU A  26
THR A  55
THR A  54
 None
 1.25A 5jncB-4gmkA:
undetectable		 5jncB-4gmkA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 10 GLN A  62
VAL A  32
LEU A  26
THR A  55
THR A  54
 None
 1.23A 5ku6A-4gmkA:
undetectable		 5ku6A-4gmkA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		5 / 10 GLN A  62
VAL A  32
LEU A  26
THR A  55
THR A  54
 None
 1.22A 5ku6B-4gmkA:
undetectable		 5ku6B-4gmkA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A
(Lactobacillus
salivarius) 		4 / 8 GLY A 204
ARG A 160
ASP A 178
ASP A  87
 None
None
None
PO4  A 301 (-2.6A)
 0.99A 5vlmB-4gmkA:
undetectable		 5vlmB-4gmkA:
22.58