SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gmq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)		 4gmq PUTATIVE RIBOSOME
ASSOCIATED PROTEIN
(Chaetomium
thermophilum) 		3 / 3 VAL A 422
GLU A 426
GLU A 425
 None
 0.71A 2nv4A-4gmqA:
undetectable		 2nv4A-4gmqA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 4gmq PUTATIVE RIBOSOME
ASSOCIATED PROTEIN
(Chaetomium
thermophilum) 		4 / 8 LEU A 388
ARG A 365
GLY A 366
LYS A 369
 None
 0.88A 2xfsA-4gmqA:
undetectable		 2xfsA-4gmqA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 4gmq PUTATIVE RIBOSOME
ASSOCIATED PROTEIN
(Chaetomium
thermophilum) 		4 / 8 LEU A 388
ARG A 365
GLY A 366
LYS A 369
 None
 0.84A 2xh9A-4gmqA:
undetectable		 2xh9A-4gmqA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 4gmq PUTATIVE RIBOSOME
ASSOCIATED PROTEIN
(Chaetomium
thermophilum) 		3 / 3 ASP A 392
ARG A 365
ASP A 385
 None
 0.75A 4fp9A-4gmqA:
undetectable		 4fp9A-4gmqA:
16.47