SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gn2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC1383_1
(CES1 PROTEIN)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		4 / 5 TRP A 157
PRO A  68
GLY A 210
LYS A 208
 KCX  A  66 ( 4.2A)
KCX  A  66 ( 4.5A)
None
KCX  A  66 ( 4.5A)
 1.49A 1ya4C-4gn2A:
1.6		 1ya4C-4gn2A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		4 / 7 PHE A  65
SER A 161
PHE A 129
GLY A 137
 None
 0.75A 2v0mC-4gn2A:
undetectable		 2v0mC-4gn2A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		5 / 12 SER A 144
GLN A 169
THR A  64
ASN A 140
PHE A  65
 None
 1.25A 2vdyA-4gn2A:
undetectable		 2vdyA-4gn2A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		5 / 12 SER A 144
GLN A 169
THR A  64
ASN A 140
PHE A  65
 None
 1.27A 2vdyB-4gn2A:
undetectable		 2vdyB-4gn2A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		5 / 12 THR A 121
TRP A 157
LEU A 162
ILE A 143
SER A 156
 None
KCX  A  66 ( 4.2A)
None
None
None
 1.45A 2ydoA-4gn2A:
undetectable		 2ydoA-4gn2A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		5 / 12 SER A 112
LYS A 208
THR A 209
GLY A 210
GLY A 212
 KCX  A  66 ( 3.5A)
KCX  A  66 ( 4.5A)
None
None
None
 0.23A 3hlwB-4gn2A:
18.0		 3hlwB-4gn2A:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		7 / 12 SER A  63
SER A 112
LYS A 208
THR A 209
GLY A 210
THR A 211
GLY A 212
 KCX  A  66 ( 2.9A)
KCX  A  66 ( 3.5A)
KCX  A  66 ( 4.5A)
None
None
None
None
 0.47A 3ny4A-4gn2A:
17.4		 3ny4A-4gn2A:
27.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOF_A_HQEA200_1
(FLAVOREDOXIN)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A  96
VAL A 114
ARG A 122
HIS A 155
 None
KCX  A  66 ( 3.6A)
None
None
 1.45A 3zofA-4gn2A:
0.0		 3zofA-4gn2A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		5 / 12 SER A 144
GLN A 169
THR A  64
ASN A 140
PHE A  65
 None
 1.32A 4c49B-4gn2A:
undetectable		 4c49B-4gn2A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		5 / 12 SER A 144
GLN A 169
THR A  64
ASN A 140
PHE A  65
 None
 1.29A 4c49C-4gn2A:
undetectable		 4c49C-4gn2A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		5 / 12 SER A 144
GLN A 169
THR A  64
ASN A 140
PHE A  65
 None
 1.24A 4c49D-4gn2A:
undetectable		 4c49D-4gn2A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		3 / 3 GLY A 152
SER A 156
TRP A 157
 None
None
KCX  A  66 ( 4.2A)
 0.67A 4e7cD-4gn2A:
undetectable		 4e7cD-4gn2A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 108
GLN A 100
THR A 103
 KCX  A  66 ( 4.1A)
None
None
 0.98A 4m2xA-4gn2A:
undetectable		 4m2xA-4gn2A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 138
THR A 106
THR A 121
MET A 124
 None
 1.47A 4mbsB-4gn2A:
undetectable		 4mbsB-4gn2A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		5 / 9 PRO A  68
VAL A  71
ALA A  70
GLY A 135
PHE A 136
 KCX  A  66 ( 4.5A)
None
KCX  A  66 ( 3.5A)
None
None
 1.33A 4mm5A-4gn2A:
undetectable		 4mm5A-4gn2A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		4 / 7 LEU A  79
PRO A 105
LEU A 120
TYR A 116
 None
 0.99A 4z4fA-4gn2A:
undetectable		 4z4fA-4gn2A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		4 / 6 LYS A 149
GLU A 146
GLY A 145
GLY A 152
 None
 0.97A 5a06D-4gn2A:
undetectable		 5a06D-4gn2A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_0
(METHYLTRANSFERASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 231
VAL A 205
GLU A  48
PHE A 227
ALA A 241
 None
 1.09A 5n5dA-4gn2A:
undetectable		 5n5dA-4gn2A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		4 / 7 LEU A  79
PRO A 105
LEU A 120
TYR A 116
 None
 1.04A 5t7bA-4gn2A:
undetectable		 5t7bA-4gn2A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		5 / 12 PHE A 240
ALA A 241
ALA A  82
THR A 106
THR A  64
 None
 1.13A 5tl8A-4gn2A:
undetectable		 5tl8A-4gn2A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		4 / 4 PHE A 227
LEU A 177
LEU A 195
VAL A 239
 None
 1.24A 5xxiA-4gn2A:
undetectable		 5xxiA-4gn2A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		7 / 12 SER A  63
SER A 112
LYS A 208
THR A 209
GLY A 210
THR A 211
GLY A 212
 KCX  A  66 ( 2.9A)
KCX  A  66 ( 3.5A)
KCX  A  66 ( 4.5A)
None
None
None
None
 0.43A 6b5yB-4gn2A:
17.4		 6b5yB-4gn2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		7 / 12 SER A  63
SER A 112
LYS A 208
THR A 209
GLY A 210
THR A 211
GLY A 212
 KCX  A  66 ( 2.9A)
KCX  A  66 ( 3.5A)
KCX  A  66 ( 4.5A)
None
None
None
None
 0.46A 6b5yD-4gn2A:
17.4		 6b5yD-4gn2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		7 / 12 SER A  63
SER A 112
LYS A 208
THR A 209
GLY A 210
THR A 211
GLY A 212
 KCX  A  66 ( 2.9A)
KCX  A  66 ( 3.5A)
KCX  A  66 ( 4.5A)
None
None
None
None
 0.31A 6b68B-4gn2A:
16.8		 6b68B-4gn2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		6 / 12 SER A  63
SER A 112
LYS A 208
GLY A 210
THR A 211
GLY A 212
 KCX  A  66 ( 2.9A)
KCX  A  66 ( 3.5A)
KCX  A  66 ( 4.5A)
None
None
None
 0.35A 6b68D-4gn2A:
17.3		 6b68D-4gn2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		7 / 12 SER A  63
SER A 112
LYS A 208
THR A 209
GLY A 210
THR A 211
GLY A 212
 KCX  A  66 ( 2.9A)
KCX  A  66 ( 3.5A)
KCX  A  66 ( 4.5A)
None
None
None
None
 0.33A 6b69A-4gn2A:
17.4
6b69B-4gn2A:
17.4		 6b69A-4gn2A:
20.81
6b69B-4gn2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		7 / 12 SER A  63
SER A 112
LYS A 208
THR A 209
GLY A 210
THR A 211
GLY A 212
 KCX  A  66 ( 2.9A)
KCX  A  66 ( 3.5A)
KCX  A  66 ( 4.5A)
None
None
None
None
 0.31A 6b69D-4gn2A:
17.3		 6b69D-4gn2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		7 / 12 SER A  63
SER A 112
LYS A 208
THR A 209
GLY A 210
THR A 211
GLY A 212
 KCX  A  66 ( 2.9A)
KCX  A  66 ( 3.5A)
KCX  A  66 ( 4.5A)
None
None
None
None
 0.32A 6b6aB-4gn2A:
17.3		 6b6aB-4gn2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		7 / 12 SER A  63
SER A 112
LYS A 208
THR A 209
GLY A 210
THR A 211
GLY A 212
 KCX  A  66 ( 2.9A)
KCX  A  66 ( 3.5A)
KCX  A  66 ( 4.5A)
None
None
None
None
 0.31A 6b6aD-4gn2A:
17.2		 6b6aD-4gn2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		7 / 12 SER A  63
SER A 112
LYS A 208
THR A 209
GLY A 210
THR A 211
GLY A 212
 KCX  A  66 ( 2.9A)
KCX  A  66 ( 3.5A)
KCX  A  66 ( 4.5A)
None
None
None
None
 0.44A 6b6cA-4gn2A:
17.2		 6b6cA-4gn2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		7 / 12 SER A  63
SER A 112
LYS A 208
THR A 209
GLY A 210
THR A 211
GLY A 212
 KCX  A  66 ( 2.9A)
KCX  A  66 ( 3.5A)
KCX  A  66 ( 4.5A)
None
None
None
None
 0.58A 6b6dA-4gn2A:
17.1		 6b6dA-4gn2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		7 / 12 SER A  63
SER A 112
LYS A 208
THR A 209
GLY A 210
THR A 211
GLY A 212
 KCX  A  66 ( 2.9A)
KCX  A  66 ( 3.5A)
KCX  A  66 ( 4.5A)
None
None
None
None
 0.38A 6b6eA-4gn2A:
17.3		 6b6eA-4gn2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 4gn2 OXACILLINASE
(Pseudomonas
aeruginosa) 		7 / 12 SER A  63
SER A 112
LYS A 208
THR A 209
GLY A 210
THR A 211
GLY A 212
 KCX  A  66 ( 2.9A)
KCX  A  66 ( 3.5A)
KCX  A  66 ( 4.5A)
None
None
None
None
 0.50A 6b6fA-4gn2A:
17.0		 6b6fA-4gn2A:
20.81