SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4go5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 4go5 ASPARTOKINASE
(Mycobacterium
tuberculosis) 		6 / 10 ALA X 155
ALA X 118
LEU X 119
LEU X 152
ALA X 148
VAL X   9
 None
 1.44A 2bxgB-4go5X:
undetectable		 2bxgB-4go5X:
16.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 4go5 ASPARTOKINASE
(Mycobacterium
tuberculosis) 		4 / 8 ASP X  25
GLY X  28
ALA X  30
GLN X  49
 None
 0.53A 2dtjA-4go5X:
22.2
2dtjB-4go5X:
22.3		 2dtjA-4go5X:
61.50
2dtjB-4go5X:
61.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 4go5 ASPARTOKINASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU X 119
VAL X 124
GLY X 123
LEU X 152
ALA X 148
 None
 0.91A 2egvA-4go5X:
undetectable		 2egvA-4go5X:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 4go5 ASPARTOKINASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU X 119
VAL X 124
GLY X 123
LEU X 152
ALA X 148
 None
 0.93A 2egvB-4go5X:
undetectable		 2egvB-4go5X:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 4go5 ASPARTOKINASE
(Mycobacterium
tuberculosis) 		5 / 12 CYH X  65
SER X  66
ALA X  73
ASN X  43
ILE X  44
 None
 1.11A 3a3bA-4go5X:
undetectable		 3a3bA-4go5X:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 4go5 ASPARTOKINASE
(Mycobacterium
tuberculosis) 		3 / 3 TYR X  91
GLY X  70
PRO X  71
 None
 0.66A 4qwpA-4go5X:
undetectable		 4qwpA-4go5X:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 4go5 ASPARTOKINASE
(Mycobacterium
tuberculosis) 		3 / 3 ARG X 135
ILE X 101
SER X  99
 None
 0.82A 5zw2A-4go5X:
undetectable		 5zw2A-4go5X:
22.33