SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4go6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 4go6 HCF C-TERMINAL CHAIN
1
(Homo
sapiens) 		5 / 12 VAL B1815
TYR B1828
LEU B1856
SER B1878
VAL B1825
 None
 1.36A 3frqA-4go6B:
undetectable		 3frqA-4go6B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 4go6 HCF C-TERMINAL CHAIN
1
(Homo
sapiens) 		3 / 3 HIS B1827
LYS B1852
PHE B1829
 None
 1.16A 5klaA-4go6B:
undetectable		 5klaA-4go6B:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4go6 HCF C-TERMINAL CHAIN
1
(Homo
sapiens) 		4 / 6 LEU B1908
VAL B1961
LEU B1966
VAL B1951
 None
 0.85A 5x7zA-4go6B:
undetectable		 5x7zA-4go6B:
26.41