SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4goj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4goj PROTEIN UNC-119
HOMOLOG A
(Homo
sapiens) 		4 / 6 SER C 218
PHE C  88
PHE C 159
GLU C 163
 None
 1.11A 1kqbA-4gojC:
undetectable
1kqbB-4gojC:
undetectable		 1kqbA-4gojC:
19.11
1kqbB-4gojC:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4goj PROTEIN UNC-119
HOMOLOG A
(Homo
sapiens) 		4 / 6 SER C 218
PHE C  88
PHE C 159
GLU C 163
 None
 1.17A 1kqbC-4gojC:
undetectable
1kqbD-4gojC:
undetectable		 1kqbC-4gojC:
19.11
1kqbD-4gojC:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4goj PROTEIN UNC-119
HOMOLOG A
(Homo
sapiens) 		5 / 12 PHE C 159
PHE C 149
HIS C 192
SER C 218
TYR C 220
 None
 1.45A 3apvA-4gojC:
undetectable		 3apvA-4gojC:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4goj PROTEIN UNC-119
HOMOLOG A
(Homo
sapiens) 		5 / 12 PHE C 159
PHE C 149
HIS C 192
SER C 218
TYR C 220
 None
 1.45A 3apvB-4gojC:
undetectable		 3apvB-4gojC:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 4goj PROTEIN UNC-119
HOMOLOG A
(Homo
sapiens) 		4 / 8 ALA C 232
SER C 216
SER C 218
TYR C 131
 None
 1.11A 3rodA-4gojC:
undetectable		 3rodA-4gojC:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 4goj PROTEIN UNC-119
HOMOLOG A
(Homo
sapiens) 		4 / 7 THR C 134
TYR C 236
PRO C 135
SER C 235
 None
 1.30A 5b6iA-4gojC:
undetectable		 5b6iA-4gojC:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 4goj PROTEIN UNC-119
HOMOLOG A
(Homo
sapiens) 		3 / 3 ASN C 157
TYR C  84
CYH C 182
 None
 1.09A 5lsuB-4gojC:
undetectable		 5lsuB-4gojC:
21.58