SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4goq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 4goq HYPOTHETICAL PROTEIN
(Caulobacter
vibrioides) 		4 / 7 THR A  55
SER A  52
ARG A  61
LEU A  37
 None
None
GOL  A 202 (-4.3A)
None
 0.88A 1ibgL-4goqA:
undetectable		 1ibgL-4goqA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4goq HYPOTHETICAL PROTEIN
(Caulobacter
vibrioides) 		4 / 6 VAL A  36
LEU A  12
PHE A  51
HIS A 101
 None
 1.21A 2f8dA-4goqA:
undetectable		 2f8dA-4goqA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 4goq HYPOTHETICAL PROTEIN
(Caulobacter
vibrioides) 		5 / 12 ARG A  27
ILE A  89
ILE A   7
SER A   4
ALA A  10
 None
None
None
GOL  A 201 (-3.6A)
None
 1.08A 3axtA-4goqA:
undetectable		 3axtA-4goqA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_1
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 4goq HYPOTHETICAL PROTEIN
(Caulobacter
vibrioides) 		4 / 5 HIS A 101
THR A 104
GLU A 105
ARG A  15
 None
None
GOL  A 202 ( 3.9A)
None
 1.22A 4hvcB-4goqA:
undetectable		 4hvcB-4goqA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 4goq HYPOTHETICAL PROTEIN
(Caulobacter
vibrioides) 		3 / 3 ARG A  14
LEU A  18
GLU A  17
 None
 0.65A 4l3gF-4goqA:
undetectable		 4l3gF-4goqA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 4goq HYPOTHETICAL PROTEIN
(Caulobacter
vibrioides) 		4 / 6 ASP A  74
ASP A  42
ARG A  49
GLN A  65
 None
 1.28A 5l6eA-4goqA:
undetectable		 5l6eA-4goqA:
20.37