SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4got'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY5_A_ACTA600_0
(RIBONUCLEASE A)		 4got METHIONINE-BINDING
LIPOPROTEIN METQ
(Bacillus
subtilis) 		4 / 4 HIS A  42
VAL A 204
ASN A 205
THR A  40
 None
 1.25A 1dy5A-4gotA:
undetectable		 1dy5A-4gotA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 4got METHIONINE-BINDING
LIPOPROTEIN METQ
(Bacillus
subtilis) 		4 / 8 ASP A  67
TYR A 206
TYR A  90
HIS A  87
 None
 1.36A 2ha2A-4gotA:
undetectable		 2ha2A-4gotA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 4got METHIONINE-BINDING
LIPOPROTEIN METQ
(Bacillus
subtilis) 		4 / 8 ASP A  67
TYR A 206
TYR A  90
HIS A  87
 None
 1.35A 2ha2B-4gotA:
undetectable		 2ha2B-4gotA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9H_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE)		 4got METHIONINE-BINDING
LIPOPROTEIN METQ
(Bacillus
subtilis) 		5 / 10 ALA A  82
LEU A 248
LEU A  60
VAL A  62
ILE A  45
 None
 1.15A 2w9hA-4gotA:
undetectable		 2w9hA-4gotA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 4got METHIONINE-BINDING
LIPOPROTEIN METQ
(Bacillus
subtilis) 		3 / 3 ASP A 198
GLU A 179
GLY A 130
 None
 0.67A 3w9tA-4gotA:
undetectable		 3w9tA-4gotA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 4got METHIONINE-BINDING
LIPOPROTEIN METQ
(Bacillus
subtilis) 		5 / 12 ALA A 230
ILE A  45
LEU A 270
HIS A 253
ILE A 257
 None
 0.98A 4azvA-4gotA:
undetectable		 4azvA-4gotA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 4got METHIONINE-BINDING
LIPOPROTEIN METQ
(Bacillus
subtilis) 		4 / 8 LEU A 248
ASN A  83
ALA A  82
VAL A  80
 None
 0.88A 4zbqA-4gotA:
undetectable		 4zbqA-4gotA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4got METHIONINE-BINDING
LIPOPROTEIN METQ
(Bacillus
subtilis) 		4 / 6 ALA A  37
VAL A  35
VAL A 109
HIS A  42
 None
 0.95A 5eclA-4gotA:
undetectable		 5eclA-4gotA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 4got METHIONINE-BINDING
LIPOPROTEIN METQ
(Bacillus
subtilis) 		4 / 7 VAL A  35
ALA A  82
LEU A  60
LEU A  53
 None
 0.67A 5jq7A-4gotA:
undetectable		 5jq7A-4gotA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 4got METHIONINE-BINDING
LIPOPROTEIN METQ
(Bacillus
subtilis) 		5 / 12 LYS A  73
GLU A  92
GLU A  94
LEU A  91
LEU A 103
 None
 1.14A 5nwvA-4gotA:
undetectable		 5nwvA-4gotA:
12.44