SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gqw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 4gqw CBS
DOMAIN-CONTAINING
PROTEIN CBSX1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 ASP A 126
LEU A 174
ALA A  99
LEU A 103
 None
 1.07A 1nh8A-4gqwA:
undetectable		 1nh8A-4gqwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4gqw CBS
DOMAIN-CONTAINING
PROTEIN CBSX1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ILE A 215
THR A 217
THR A  82
ILE A 108
PRO A 112
 None
 0.99A 3kpbA-4gqwA:
16.7		 3kpbA-4gqwA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4gqw CBS
DOMAIN-CONTAINING
PROTEIN CBSX1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ILE A 215
THR A 217
THR A  82
ILE A 108
PRO A 112
 None
 0.94A 3kpbC-4gqwA:
16.7		 3kpbC-4gqwA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4gqw CBS
DOMAIN-CONTAINING
PROTEIN CBSX1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ILE A 215
THR A 217
THR A  82
ILE A 108
PRO A 112
 None
 1.10A 3kpdB-4gqwA:
16.2		 3kpdB-4gqwA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)		 4gqw CBS
DOMAIN-CONTAINING
PROTEIN CBSX1,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 ARG A 107
PHE A 111
ILE A 215
THR A  82
 None
 1.16A 5vceA-4gqwA:
undetectable		 5vceA-4gqwA:
15.94