SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gqy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTI_D_CCSD47_0 (GLUTATHIONE S-TRANSFERASE)	4gqy	CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC (Arabidopsis thaliana)	4 / 7	THR A 178 LEU A 176 GLY A 174 LYS A 163	AMP A 301 (-3.4A) None None None	1.06A	1gtiD-4gqyA: undetectable	1gtiD-4gqyA: 23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTI_E_CCSE47_0 (GLUTATHIONE S-TRANSFERASE)	4gqy	CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC (Arabidopsis thaliana)	4 / 7	THR A 178 LEU A 176 GLY A 174 LYS A 163	AMP A 301 (-3.4A) None None None	1.01A	1gtiE-4gqyA: undetectable	1gtiE-4gqyA: 23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3H52_A_486A3_1 (GLUCOCORTICOID RECEPTOR)	4gqy	CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC (Arabidopsis thaliana)	5 / 12	LEU A 218 GLY A 80 ARG A 225 LEU A 89 ILE A 215	None	1.33A	3h52A-4gqyA: undetectable	3h52A-4gqyA: 20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UUU_B_SAMB1548_0 (CYSTATHIONINE BETA-SYNTHASE)	4gqy	CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC (Arabidopsis thaliana)	5 / 11	LEU A 182 PHE A 202 PRO A 206 VAL A 125 ASP A 130	AMP A 301 (-4.3A) AMP A 301 (-3.5A) AMP A 301 (-4.6A) AMP A 301 (-4.5A) AMP A 301 (-2.8A)	1.06A	4uuuB-4gqyA: 14.6	4uuuB-4gqyA: 24.29

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GTI_D_CCSD47_0","GLUTATHIONE S-TRANSFERASE","4gqy","CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC","Arabidopsis thaliana",4,"THR A 178;LEU A 176;GLY A 174;LYS A 163","AMP A 301 (-3.4A);None;None;None","1.06A","1gtiD-4gqyA:undetectable","1gtiD-4gqyA:23.74"],["1GTI_E_CCSE47_0","GLUTATHIONE S-TRANSFERASE","4gqy","CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC","Arabidopsis thaliana",4,"THR A 178;LEU A 176;GLY A 174;LYS A 163","AMP A 301 (-3.4A);None;None;None","1.01A","1gtiE-4gqyA:undetectable","1gtiE-4gqyA:23.74"],["3H52_A_486A3_1","GLUCOCORTICOID RECEPTOR","4gqy","CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC","Arabidopsis thaliana",5,"LEU A 218;GLY A  80;ARG A 225;LEU A  89;ILE A 215","None","1.33A","3h52A-4gqyA:undetectable","3h52A-4gqyA:20.93"],["4UUU_B_SAMB1548_0","CYSTATHIONINE BETA-SYNTHASE","4gqy","CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC","Arabidopsis thaliana",5,"LEU A 182;PHE A 202;PRO A 206;VAL A 125;ASP A 130","AMP A 301 (-4.3A);AMP A 301 (-3.5A);AMP A 301 (-4.6A);AMP A 301 (-4.5A);AMP A 301 (-2.8A)","1.06A","4uuuB-4gqyA:14.6","4uuuB-4gqyA:24.29"]]