SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gqz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_0
(N,N-DIMETHYLGLYCINE
OXIDASE)		 4gqz PUTATIVE PERIPLASMIC
OR EXPORTED PROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 101
TYR A  83
ASN A 135
LEU A  65
TYR A  56
 None
 1.32A 1pj7A-4gqzA:
undetectable		 1pj7A-4gqzA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 4gqz PUTATIVE PERIPLASMIC
OR EXPORTED PROTEIN
(Salmonella
enterica) 		4 / 8 GLY A 136
ASN A 135
PHE A  86
TYR A 133
 None
 1.32A 3ccfA-4gqzA:
undetectable		 3ccfA-4gqzA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 4gqz PUTATIVE PERIPLASMIC
OR EXPORTED PROTEIN
(Salmonella
enterica) 		4 / 7 LEU A  54
GLN A  40
LEU A  78
LEU A  67
 None
 0.77A 3g8iA-4gqzA:
undetectable		 3g8iA-4gqzA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 4gqz PUTATIVE PERIPLASMIC
OR EXPORTED PROTEIN
(Salmonella
enterica) 		4 / 8 THR A 174
PRO A  88
GLY A 136
PHE A 137
 None
 0.92A 3tzfB-4gqzA:
undetectable		 3tzfB-4gqzA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4gqz PUTATIVE PERIPLASMIC
OR EXPORTED PROTEIN
(Salmonella
enterica) 		4 / 8 GLU A 107
TYR A  89
GLU A  90
TYR A 133
 None
 1.15A 4mj8A-4gqzA:
undetectable
4mj8C-4gqzA:
undetectable		 4mj8A-4gqzA:
20.62
4mj8C-4gqzA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 4gqz PUTATIVE PERIPLASMIC
OR EXPORTED PROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 142
PHE A  82
LEU A  78
LYS A  66
ALA A  58
 None
 1.02A 4rtbA-4gqzA:
undetectable		 4rtbA-4gqzA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 4gqz PUTATIVE PERIPLASMIC
OR EXPORTED PROTEIN
(Salmonella
enterica) 		3 / 3 THR A  61
THR A 171
PHE A  97
 None
 0.73A 5cxvA-4gqzA:
undetectable		 5cxvA-4gqzA:
15.07