SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gr6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4gr6 ATRBCX2
(Arabidopsis
thaliana) 		4 / 8 ARG A  80
PHE A  61
ASN A  21
ASP A  57
 None
 1.29A 1p6kA-4gr6A:
undetectable		 1p6kA-4gr6A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4gr6 ATRBCX2
(Arabidopsis
thaliana) 		4 / 8 ARG A  80
PHE A  61
ASN A  21
ASP A  57
 None
 1.25A 1rs6A-4gr6A:
2.4		 1rs6A-4gr6A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4gr6 ATRBCX2
(Arabidopsis
thaliana) 		4 / 8 ARG A  80
PHE A  61
ASN A  21
ASP A  57
 None
 1.21A 1rs6B-4gr6A:
2.0		 1rs6B-4gr6A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4gr6 ATRBCX2
(Arabidopsis
thaliana) 		4 / 8 ARG A  80
PHE A  61
ASN A  21
ASP A  57
 None
 1.30A 1rs7B-4gr6A:
undetectable		 1rs7B-4gr6A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4gr6 ATRBCX2
(Arabidopsis
thaliana) 		4 / 8 ARG A  80
PHE A  61
ASN A  21
ASP A  57
 None
 1.26A 1zzqB-4gr6A:
undetectable		 1zzqB-4gr6A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 4gr6 ATRBCX2
(Arabidopsis
thaliana) 		4 / 8 ARG A  80
PHE A  61
ASN A  21
ASP A  57
 None
 1.17A 3n62B-4gr6A:
undetectable		 3n62B-4gr6A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 4gr6 ATRBCX2
(Arabidopsis
thaliana) 		4 / 8 ARG A  80
PHE A  61
ASN A  21
ASP A  57
 None
 1.18A 3n66B-4gr6A:
undetectable		 3n66B-4gr6A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 4gr6 ATRBCX2
(Arabidopsis
thaliana) 		4 / 7 PHE A  46
ALA A  27
THR A  24
LEU A  62
 None
 1.11A 3t3sC-4gr6A:
2.1		 3t3sC-4gr6A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4gr6 ATRBCX2
(Arabidopsis
thaliana) 		4 / 8 ARG A  80
PHE A  61
ASN A  21
ASP A  57
 None
 1.23A 5vunA-4gr6A:
undetectable		 5vunA-4gr6A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4gr6 ATRBCX2
(Arabidopsis
thaliana) 		4 / 8 ARG A  80
PHE A  61
ASN A  21
ASP A  57
 None
 1.22A 5vunB-4gr6A:
undetectable		 5vunB-4gr6A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4gr6 ATRBCX2
(Arabidopsis
thaliana) 		4 / 8 ARG A  80
PHE A  61
ASN A  21
ASP A  57
 None
 1.25A 5vuoB-4gr6A:
undetectable		 5vuoB-4gr6A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4gr6 ATRBCX2
(Arabidopsis
thaliana) 		4 / 8 ARG A  80
PHE A  61
ASN A  21
ASP A  57
 None
 1.22A 6auuB-4gr6A:
undetectable		 6auuB-4gr6A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4gr6 ATRBCX2
(Arabidopsis
thaliana) 		4 / 7 ALA A  27
THR A  24
TYR A  25
VAL A  31
 None
 0.95A 6cduA-4gr6A:
undetectable
6cduE-4gr6A:
undetectable		 6cduA-4gr6A:
18.30
6cduE-4gr6A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4gr6 ATRBCX2
(Arabidopsis
thaliana) 		4 / 7 VAL A  31
ALA A  27
THR A  24
TYR A  25
 None
 0.91A 6cduH-4gr6A:
undetectable
6cduI-4gr6A:
undetectable		 6cduH-4gr6A:
18.30
6cduI-4gr6A:
18.30