SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4guj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 4guj 3-DEHYDROQUINATE
DEHYDRATASE
(Salmonella
enterica) 		5 / 12 MET A 203
ALA A 172
HIS A 143
GLU A  86
ASP A 114
 SKM  A 301 ( 4.3A)
SKM  A 301 ( 4.3A)
SKM  A 301 (-3.8A)
None
None
 1.47A 1a4lB-4gujA:
5.6		 1a4lB-4gujA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 4guj 3-DEHYDROQUINATE
DEHYDRATASE
(Salmonella
enterica) 		4 / 7 LEU A 182
SER A 204
THR A 208
SER A 206
 None
 1.00A 4iklA-4gujA:
undetectable
4iklB-4gujA:
undetectable		 4iklA-4gujA:
16.73
4iklB-4gujA:
16.73