SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gvb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 4gvb KP6 KILLER TOXIN
SUBUNIT BETA
(Ustilago
maydis
virus
P6) 		3 / 3 ARG B  47
SER B  68
TYR B  67
 None
 0.75A 1x70A-4gvbB:
undetectable		 1x70A-4gvbB:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 4gvb KP6 KILLER TOXIN
SUBUNIT BETA
(Ustilago
maydis
virus
P6) 		4 / 5 PHE B  55
PRO B   6
VAL B   7
ALA B  48
 None
 1.09A 4w5oA-4gvbB:
undetectable		 4w5oA-4gvbB:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4gvb KP6 KILLER TOXIN
SUBUNIT BETA
(Ustilago
maydis
virus
P6) 		4 / 5 PHE B  55
PRO B   6
VAL B   7
ALA B  48
 None
 1.07A 4z4cA-4gvbB:
undetectable		 4z4cA-4gvbB:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4gvb KP6 KILLER TOXIN
SUBUNIT BETA
(Ustilago
maydis
virus
P6) 		4 / 5 PHE B  55
PRO B   6
VAL B   7
ALA B  48
 None
 1.09A 4z4dA-4gvbB:
undetectable		 4z4dA-4gvbB:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 4gvb KP6 KILLER TOXIN
SUBUNIT BETA
(Ustilago
maydis
virus
P6) 		4 / 6 PHE B  55
PRO B   6
VAL B   7
ALA B  48
 None
 1.04A 5t7bA-4gvbB:
undetectable		 5t7bA-4gvbB:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 4gvb KP6 KILLER TOXIN
SUBUNIT BETA
(Ustilago
maydis
virus
P6) 		3 / 3 PHE B  45
ARG B  47
GLN B  75
 None
 0.84A 6g1pB-4gvbB:
undetectable		 6g1pB-4gvbB:
11.34