SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gvo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F6D_A_ACRA996_1 (GLUCOAMYLASE GLU1)	4gvo	LMO2349 PROTEIN (Listeria monocytogenes)	4 / 7	HIS A 101 ASN A 86 THR A 43 GLY A 42	CSX A 704 ( 4.5A) None None None	1.03A	2f6dA-4gvoA: undetectable	2f6dA-4gvoA: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DH0_B_SAMB300_0 (SAM DEPENDENT METHYLTRANSFERASE)	4gvo	LMO2349 PROTEIN (Listeria monocytogenes)	5 / 12	PHE A 45 GLY A 42 VAL A 62 THR A 43 LEU A 51	HIS A 703 ( 4.0A) None None None None	1.12A	3dh0B-4gvoA: undetectable	3dh0B-4gvoA: 23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DL9_A_V2HA602_0 (CYTOCHROME P450 2R1)	4gvo	LMO2349 PROTEIN (Listeria monocytogenes)	5 / 12	MET A 103 PHE A 45 VAL A 48 ILE A 195 THR A 182	CSX A 704 ( 4.4A) HIS A 703 ( 4.0A) None None None	1.25A	3dl9A-4gvoA: undetectable	3dl9A-4gvoA: 22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JVL_A_ESTA702_1 (ESTROGEN SULFOTRANSFERASE)	4gvo	LMO2349 PROTEIN (Listeria monocytogenes)	4 / 9	PHE A 84 HIS A 101 PHE A 123 ILE A 195	HIS A 703 ( 3.7A) CSX A 704 ( 4.5A) CSX A 704 ( 3.4A) None	1.30A	4jvlA-4gvoA: undetectable	4jvlA-4gvoA: 18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWV_A_ACAA18_1 (SCRFP-TAG,GP41)	4gvo	LMO2349 PROTEIN (Listeria monocytogenes)	5 / 12	GLY A 92 LYS A 112 LEU A 114 GLU A 232 LEU A 228	None	1.33A	5nwvA-4gvoA: undetectable	5nwvA-4gvoA: 9.05

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2F6D_A_ACRA996_1","GLUCOAMYLASE GLU1","4gvo","LMO2349 PROTEIN","Listeria monocytogenes",4,"HIS A 101;ASN A  86;THR A  43;GLY A  42","CSX A 704 ( 4.5A);None;None;None","1.03A","2f6dA-4gvoA:undetectable","2f6dA-4gvoA:21.14"],["3DH0_B_SAMB300_0","SAM DEPENDENT METHYLTRANSFERASE","4gvo","LMO2349 PROTEIN","Listeria monocytogenes",5,"PHE A  45;GLY A  42;VAL A  62;THR A  43;LEU A  51","HIS A 703 ( 4.0A);None;None;None;None","1.12A","3dh0B-4gvoA:undetectable","3dh0B-4gvoA:23.77"],["3DL9_A_V2HA602_0","CYTOCHROME P450 2R1","4gvo","LMO2349 PROTEIN","Listeria monocytogenes",5,"MET A 103;PHE A  45;VAL A  48;ILE A 195;THR A 182","CSX A 704 ( 4.4A);HIS A 703 ( 4.0A);None;None;None","1.25A","3dl9A-4gvoA:undetectable","3dl9A-4gvoA:22.15"],["4JVL_A_ESTA702_1","ESTROGEN SULFOTRANSFERASE","4gvo","LMO2349 PROTEIN","Listeria monocytogenes",4,"PHE A  84;HIS A 101;PHE A 123;ILE A 195","HIS A 703 ( 3.7A);CSX A 704 ( 4.5A);CSX A 704 ( 3.4A);None","1.30A","4jvlA-4gvoA:undetectable","4jvlA-4gvoA:18.87"],["5NWV_A_ACAA18_1","SCRFP-TAG,GP41","4gvo","LMO2349 PROTEIN","Listeria monocytogenes",5,"GLY A  92;LYS A 112;LEU A 114;GLU A 232;LEU A 228","None","1.33A","5nwvA-4gvoA:undetectable","5nwvA-4gvoA:9.05"]]