SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gxh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4gxh PYRROLIDONE-CARBOXYL
ATE PEPTIDASE
(Xenorhabdus
bovienii) 		4 / 8 PHE A 141
ILE A  91
GLY A  13
GLY A  14
 None
 0.74A 2qx4A-4gxhA:
3.7
2qx4B-4gxhA:
4.3		 2qx4A-4gxhA:
23.05
2qx4B-4gxhA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4gxh PYRROLIDONE-CARBOXYL
ATE PEPTIDASE
(Xenorhabdus
bovienii) 		4 / 6 PHE A 141
ILE A  91
GLY A  13
GLY A  14
 None
 0.73A 2qx6A-4gxhA:
4.4
2qx6B-4gxhA:
4.4		 2qx6A-4gxhA:
23.05
2qx6B-4gxhA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 4gxh PYRROLIDONE-CARBOXYL
ATE PEPTIDASE
(Xenorhabdus
bovienii) 		5 / 12 ASN A  36
LEU A  64
VAL A   6
ILE A  66
LEU A 193
 None
 1.43A 4k36A-4gxhA:
undetectable		 4k36A-4gxhA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4gxh PYRROLIDONE-CARBOXYL
ATE PEPTIDASE
(Xenorhabdus
bovienii) 		4 / 8 LEU A  27
VAL A   6
VAL A 168
ILE A 166
 None
 0.98A 4l4cB-4gxhA:
undetectable		 4l4cB-4gxhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4gxh PYRROLIDONE-CARBOXYL
ATE PEPTIDASE
(Xenorhabdus
bovienii) 		5 / 11 GLY A  13
GLY A  14
GLY A  96
PHE A 141
ILE A  91
 None
 1.11A 4qoiA-4gxhA:
3.8
4qoiB-4gxhA:
3.6		 4qoiA-4gxhA:
23.14
4qoiB-4gxhA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_E_ADNE401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 4gxh PYRROLIDONE-CARBOXYL
ATE PEPTIDASE
(Xenorhabdus
bovienii) 		5 / 10 GLY A 163
VAL A  65
ILE A  42
VAL A 146
LEU A  53
 None
 0.78A 5lw1E-4gxhA:
undetectable		 5lw1E-4gxhA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4gxh PYRROLIDONE-CARBOXYL
ATE PEPTIDASE
(Xenorhabdus
bovienii) 		5 / 10 ILE A   4
ILE A 130
ALA A 192
LEU A 193
ALA A  23
 None
 1.30A 5zjiB-4gxhA:
undetectable		 5zjiB-4gxhA:
18.10