SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gxz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 4gxz SUPPRESSION OF
COPPER SENSITIVITY
PROTEIN
(Salmonella
enterica) 		4 / 8 GLN A 146
ASN A 144
LEU A 147
LEU A  90
 None
 1.15A 1hk2A-4gxzA:
undetectable		 1hk2A-4gxzA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 4gxz SUPPRESSION OF
COPPER SENSITIVITY
PROTEIN
(Salmonella
enterica) 		4 / 5 LEU A  90
ARG A  87
ALA A  89
ILE A 141
 None
 1.01A 2qhfA-4gxzA:
undetectable		 2qhfA-4gxzA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 4gxz SUPPRESSION OF
COPPER SENSITIVITY
PROTEIN
(Salmonella
enterica) 		5 / 11 ILE A 119
LEU A 107
THR A  92
VAL A 131
LEU A 133
 None
 1.19A 3a51A-4gxzA:
undetectable		 3a51A-4gxzA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 4gxz SUPPRESSION OF
COPPER SENSITIVITY
PROTEIN
(Salmonella
enterica) 		5 / 12 ILE A 119
LEU A 107
THR A  92
VAL A 131
LEU A 133
 None
 1.18A 3a51D-4gxzA:
undetectable		 3a51D-4gxzA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 4gxz SUPPRESSION OF
COPPER SENSITIVITY
PROTEIN
(Salmonella
enterica) 		5 / 12 ILE A 119
ALA A  89
THR A  92
VAL A 131
LEU A 133
 None
 1.21A 3a51E-4gxzA:
undetectable		 3a51E-4gxzA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 4gxz SUPPRESSION OF
COPPER SENSITIVITY
PROTEIN
(Salmonella
enterica) 		4 / 8 GLN A  98
GLN A  99
ALA A 102
LEU A 103
 None
 0.70A 3ozwA-4gxzA:
undetectable		 3ozwA-4gxzA:
18.27