SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gyt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4gyt UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		4 / 7 PHE A  75
PHE A  16
LEU A  25
MET A  36
 None
 1.19A 1wrlE-4gytA:
undetectable		 1wrlE-4gytA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4gyt UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		4 / 6 GLY A 113
THR A 119
GLU A  31
GLU A 109
 None
 0.97A 3fpjA-4gytA:
undetectable		 3fpjA-4gytA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4gyt UNCHARACTERIZED
PROTEIN
(Legionella
pneumophila) 		5 / 12 GLY A  34
CYH A  37
PHE A  89
MET A  82
LEU A 140
 None
 1.45A 4xldA-4gytA:
undetectable		 4xldA-4gytA:
20.95