SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gzv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q1E_D_T44D328_1 (5-HYDROXYISOURATE HYDROLASE)	4gzv	HYPOTHETICAL PROTEIN (Bacteroides ovatus)	5 / 9	HIS A 104 LEU A 105 LEU A 108 LEU A 127 LEU A 115	UNL A 200 ( 3.9A) UNL A 200 ( 4.7A) None None None	1.04A	3q1eB-4gzvA: undetectable 3q1eD-4gzvA: undetectable	3q1eB-4gzvA: 20.44 3q1eD-4gzvA: 20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RYA_A_MTLA501_1 (ABC TRANSPORTER SUBSTRATE BINDING PROTEIN (SORBITOL))	4gzv	HYPOTHETICAL PROTEIN (Bacteroides ovatus)	3 / 3	GLU A 146 TYR A 95 GLU A 97	UNL A 200 ( 3.0A) None UNL A 200 ( 2.8A)	0.69A	4ryaA-4gzvA: undetectable	4ryaA-4gzvA: 13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GH9_A_MIXA1003_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15)	4gzv	HYPOTHETICAL PROTEIN (Bacteroides ovatus)	4 / 5	ASN A 57 TYR A 42 GLY A 51 HIS A 41	None	1.27A	6gh9A-4gzvA: undetectable	6gh9A-4gzvA: 21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6H7U_A_FVTA501_0 (PEPTIDE ABC TRANSPORTER PERMEASE)	4gzv	HYPOTHETICAL PROTEIN (Bacteroides ovatus)	4 / 6	ASN A 102 ASN A 113 ILE A 99 GLU A 97	UNL A 200 ( 3.6A) None None UNL A 200 ( 2.8A)	1.19A	6h7uA-4gzvA: undetectable	6h7uA-4gzvA: 14.17

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3Q1E_D_T44D328_1","5-HYDROXYISOURATE HYDROLASE;5-HYDROXYISOURATE HYDROLASE","4gzv","HYPOTHETICAL PROTEIN","Bacteroides ovatus",5,"HIS A 104;LEU A 105;LEU A 108;LEU A 127;LEU A 115","UNL A 200 ( 3.9A);UNL A 200 ( 4.7A);None;None;None","1.04A","3q1eB-4gzvA:undetectable;3q1eD-4gzvA:undetectable","3q1eB-4gzvA:20.44;3q1eD-4gzvA:20.44"],["4RYA_A_MTLA501_1","ABC TRANSPORTER SUBSTRATE BINDING PROTEIN (SORBITOL)","4gzv","HYPOTHETICAL PROTEIN","Bacteroides ovatus",3,"GLU A 146;TYR A  95;GLU A  97","UNL A 200 ( 3.0A);None;UNL A 200 ( 2.8A)","0.69A","4ryaA-4gzvA:undetectable","4ryaA-4gzvA:13.91"],["6GH9_A_MIXA1003_0","UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15","4gzv","HYPOTHETICAL PROTEIN","Bacteroides ovatus",4,"ASN A  57;TYR A  42;GLY A  51;HIS A  41","None","1.27A","6gh9A-4gzvA:undetectable","6gh9A-4gzvA:21.74"],["6H7U_A_FVTA501_0","PEPTIDE ABC TRANSPORTER PERMEASE","4gzv","HYPOTHETICAL PROTEIN","Bacteroides ovatus",4,"ASN A 102;ASN A 113;ILE A  99;GLU A  97","UNL A 200 ( 3.6A);None;None;UNL A 200 ( 2.8A)","1.19A","6h7uA-4gzvA:undetectable","6h7uA-4gzvA:14.17"]]