SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h09'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 11 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.35A 1fkfA-4h09A:
undetectable		 1fkfA-4h09A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 11 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.32A 1fkjA-4h09A:
undetectable		 1fkjA-4h09A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		6 / 12 VAL A 239
ILE A 232
ILE A 255
ILE A 278
LEU A 289
MET A 270
 None
 1.39A 1qhsA-4h09A:
undetectable		 1qhsA-4h09A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		6 / 12 VAL A 239
ILE A 232
ILE A 255
ILE A 278
LEU A 289
MET A 270
 None
 1.32A 1qhyA-4h09A:
undetectable		 1qhyA-4h09A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 11 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.31A 1tcoC-4h09A:
undetectable		 1tcoC-4h09A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 11 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.25A 1yatA-4h09A:
undetectable		 1yatA-4h09A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 11 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.31A 2fkeA-4h09A:
undetectable		 2fkeA-4h09A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M9Q_B_BEZB251_0
(SERINE PROTEASE
INHIBITOR
SERINE PROTEASE
SUBUNIT NS2B, SERINE
PROTEASE NS3)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 9 ILE A  55
ILE A  43
PHE A  96
VAL A  39
LEU A  53
 None
 1.13A 2m9qA-4h09A:
undetectable		 2m9qA-4h09A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		4 / 4 ALA A  94
VAL A 140
PHE A  96
THR A 122
 EDO  A 505 ( 3.9A)
None
None
None
 1.41A 2pkkA-4h09A:
undetectable		 2pkkA-4h09A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		4 / 5 LEU A 348
PRO A 349
LEU A 352
ILE A 355
 None
 0.78A 2qd4A-4h09A:
undetectable		 2qd4A-4h09A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 11 ILE A 180
PHE A 151
GLY A 159
PHE A 163
ILE A 162
 None
 1.37A 2y7kA-4h09A:
undetectable		 2y7kA-4h09A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 ILE A 276
LEU A 296
PHE A 337
VAL A 308
VAL A 305
 None
None
None
None
EDO  A 510 ( 4.5A)
 1.14A 2ygpA-4h09A:
undetectable		 2ygpA-4h09A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 LEU A 250
LEU A 273
LEU A 296
LEU A 289
TYR A 221
 None
 1.20A 3d90B-4h09A:
undetectable		 3d90B-4h09A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 10 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.30A 3ihzA-4h09A:
undetectable		 3ihzA-4h09A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		4 / 4 GLY A 243
TYR A 242
GLY A 265
ASP A 264
 None
None
None
PEG  A 502 ( 3.5A)
 1.14A 3kl3A-4h09A:
undetectable		 3kl3A-4h09A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 10 VAL A 236
ILE A 232
ALA A 266
ILE A 278
VAL A 282
 None
 0.91A 3me6A-4h09A:
undetectable		 3me6A-4h09A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 11 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.12A 3o5rA-4h09A:
undetectable		 3o5rA-4h09A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 GLY A 137
ILE A  88
GLY A  92
ALA A 118
PHE A  96
 PEG  A 501 ( 4.0A)
None
None
None
None
 1.12A 3sudB-4h09A:
undetectable		 3sudB-4h09A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 GLY A 185
ILE A 253
GLY A 247
SER A 245
ALA A 266
 None
 0.93A 3sueA-4h09A:
undetectable		 3sueA-4h09A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 GLY A 185
ILE A 253
GLY A 247
SER A 245
ALA A 266
 None
 0.94A 3sufB-4h09A:
undetectable		 3sufB-4h09A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 GLY A 185
ILE A 253
GLY A 247
SER A 245
ALA A 266
 None
 0.96A 3sufD-4h09A:
undetectable		 3sufD-4h09A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 10 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.28A 3uf8A-4h09A:
undetectable		 3uf8A-4h09A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 10 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.33A 3uqaA-4h09A:
undetectable		 3uqaA-4h09A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 11 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.32A 3vawA-4h09A:
undetectable		 3vawA-4h09A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		4 / 7 PHE A 337
VAL A 322
PHE A 301
ILE A 285
 None
None
None
EDO  A 510 (-4.6A)
 0.96A 3zjqA-4h09A:
undetectable		 3zjqA-4h09A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		4 / 7 PHE A 337
VAL A 322
PHE A 301
ILE A 285
 None
None
None
EDO  A 510 (-4.6A)
 0.93A 3zjqB-4h09A:
undetectable		 3zjqB-4h09A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 LEU A 290
LEU A 289
ILE A 253
ILE A 278
TYR A 211
 None
 1.13A 4a7aB-4h09A:
undetectable		 4a7aB-4h09A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.16A 4drhA-4h09A:
undetectable		 4drhA-4h09A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.18A 4drhD-4h09A:
undetectable		 4drhD-4h09A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 11 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.19A 4driA-4h09A:
undetectable		 4driA-4h09A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 11 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.23A 4drjA-4h09A:
undetectable		 4drjA-4h09A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 11 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.29A 4dz2A-4h09A:
undetectable
4dz2B-4h09A:
undetectable		 4dz2A-4h09A:
17.57
4dz2B-4h09A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 11 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.29A 4dz2A-4h09A:
undetectable
4dz2B-4h09A:
undetectable		 4dz2A-4h09A:
17.57
4dz2B-4h09A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 10 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.33A 4dz3A-4h09A:
undetectable		 4dz3A-4h09A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 10 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.34A 4dz3B-4h09A:
undetectable		 4dz3B-4h09A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		4 / 4 LEU A 348
PRO A 349
LEU A 352
ILE A 355
 None
 0.87A 4f4dB-4h09A:
undetectable		 4f4dB-4h09A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 10 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.21A 4laxA-4h09A:
undetectable		 4laxA-4h09A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.26A 4nnrA-4h09A:
undetectable
4nnrB-4h09A:
undetectable		 4nnrA-4h09A:
18.13
4nnrB-4h09A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 10 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.25A 4nnrB-4h09A:
undetectable		 4nnrB-4h09A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 ILE A 375
ALA A 382
LEU A 352
LEU A 332
PHE A 383
 None
EDO  A 509 (-4.5A)
None
None
None
 1.33A 4pbhA-4h09A:
undetectable		 4pbhA-4h09A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 ILE A 375
THR A 354
ALA A 382
LEU A 352
PHE A 383
 None
None
EDO  A 509 (-4.5A)
None
None
 1.29A 4pbhA-4h09A:
undetectable		 4pbhA-4h09A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 10 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.25A 4qt2A-4h09A:
undetectable		 4qt2A-4h09A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 10 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.23A 4qt3A-4h09A:
undetectable		 4qt3A-4h09A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 LEU A 332
ILE A 355
ALA A 382
ILE A 369
PHE A 383
 None
None
EDO  A 509 (-4.5A)
None
None
 1.15A 4rp8C-4h09A:
undetectable		 4rp8C-4h09A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		4 / 4 GLY A 243
VAL A 239
PHE A 301
ILE A 285
 None
None
None
EDO  A 510 (-4.6A)
 1.10A 4xv2B-4h09A:
undetectable		 4xv2B-4h09A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		4 / 6 SER A  98
GLY A 137
ASP A 138
GLY A 115
 None
PEG  A 501 ( 4.0A)
None
PEG  A 501 (-3.6A)
 0.94A 5cdpA-4h09A:
undetectable
5cdpB-4h09A:
undetectable		 5cdpA-4h09A:
23.82
5cdpB-4h09A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 11 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.11A 5hw8G-4h09A:
undetectable		 5hw8G-4h09A:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 11 TYR A 127
VAL A 172
ILE A 171
ILE A 158
ILE A 162
 EDO  A 504 (-3.8A)
None
None
None
None
 1.22A 5hw8G-4h09A:
undetectable		 5hw8G-4h09A:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 11 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.22A 5hwcA-4h09A:
undetectable		 5hwcA-4h09A:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		4 / 6 GLY A 265
SER A 245
TYR A 242
GLY A 269
 None
None
None
EDO  A 506 (-3.9A)
 0.82A 5k4pA-4h09A:
undetectable		 5k4pA-4h09A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 GLY A 185
ILE A 253
GLY A 247
SER A 245
ALA A 266
 None
 0.89A 6c2mA-4h09A:
undetectable		 6c2mA-4h09A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_0
(NS3 PROTEASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 GLY A 185
ILE A 253
GLY A 247
SER A 245
ALA A 266
 None
 0.88A 6c2mB-4h09A:
undetectable		 6c2mB-4h09A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		4 / 6 PHE A 267
LEU A 289
ALA A 266
ASN A 281
 None
 0.99A 6f88A-4h09A:
undetectable		 6f88A-4h09A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.25A 6mkeA-4h09A:
undetectable
6mkeD-4h09A:
undetectable		 6mkeA-4h09A:
12.94
6mkeD-4h09A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 12 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.20A 6mkeB-4h09A:
undetectable
6mkeC-4h09A:
undetectable		 6mkeB-4h09A:
12.94
6mkeC-4h09A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 10 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.19A 6mkeC-4h09A:
undetectable		 6mkeC-4h09A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN
(Eubacterium
ventriosum) 		5 / 10 PHE A 337
VAL A 346
ILE A 369
ILE A 375
PHE A 383
 None
 1.24A 6mkeD-4h09A:
undetectable		 6mkeD-4h09A:
12.94