SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h0c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 4h0c PHOSPHOLIPASE/CARBOX
YLESTERASE
(Dyadobacter
fermentans) 		3 / 3 PHE A  64
LEU A 137
SER A 170
 CIT  A 301 (-4.1A)
None
None
 0.82A 1e7aA-4h0cA:
undetectable		 1e7aA-4h0cA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4h0c PHOSPHOLIPASE/CARBOX
YLESTERASE
(Dyadobacter
fermentans) 		4 / 7 GLY A 130
SER A 165
SER A 170
GLU A 169
 CIT  A 301 (-3.4A)
None
None
None
 0.90A 2c8aB-4h0cA:
undetectable		 2c8aB-4h0cA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4h0c PHOSPHOLIPASE/CARBOX
YLESTERASE
(Dyadobacter
fermentans) 		4 / 7 GLY A 130
SER A 165
SER A 170
GLU A 169
 CIT  A 301 (-3.4A)
None
None
None
 0.83A 2c8aD-4h0cA:
undetectable		 2c8aD-4h0cA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4h0c PHOSPHOLIPASE/CARBOX
YLESTERASE
(Dyadobacter
fermentans) 		5 / 10 ILE A  36
ILE A  35
PHE A 101
VAL A  85
LEU A  44
 None
 1.13A 3elzB-4h0cA:
undetectable		 3elzB-4h0cA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 4h0c PHOSPHOLIPASE/CARBOX
YLESTERASE
(Dyadobacter
fermentans) 		3 / 3 PHE A 146
TYR A 114
TYR A 122
 None
 0.92A 4ffwA-4h0cA:
13.9		 4ffwA-4h0cA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 4h0c PHOSPHOLIPASE/CARBOX
YLESTERASE
(Dyadobacter
fermentans) 		4 / 7 ASP A 159
THR A 155
ARG A 189
HIS A 191
 None
None
None
CIT  A 301 (-4.2A)
 1.42A 4o4dA-4h0cA:
undetectable		 4o4dA-4h0cA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4h0c PHOSPHOLIPASE/CARBOX
YLESTERASE
(Dyadobacter
fermentans) 		5 / 12 VAL A  68
ALA A 138
ILE A 153
ARG A 117
ILE A 133
 None
 1.07A 5hbsA-4h0cA:
undetectable		 5hbsA-4h0cA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 4h0c PHOSPHOLIPASE/CARBOX
YLESTERASE
(Dyadobacter
fermentans) 		5 / 12 VAL A 171
ILE A 205
VAL A 201
SER A 182
VAL A 181
 None
 1.34A 6ap6A-4h0cA:
12.9		 6ap6A-4h0cA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 4h0c PHOSPHOLIPASE/CARBOX
YLESTERASE
(Dyadobacter
fermentans) 		5 / 12 VAL A 171
ILE A 205
VAL A 201
SER A 182
VAL A 181
 None
 1.36A 6ap6B-4h0cA:
13.0		 6ap6B-4h0cA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4h0c PHOSPHOLIPASE/CARBOX
YLESTERASE
(Dyadobacter
fermentans) 		5 / 10 SER A 154
ASP A 159
ILE A 126
SER A 105
GLY A 103
 None
None
None
CIT  A 301 (-3.1A)
None
 1.14A 6dlzA-4h0cA:
3.4
6dlzD-4h0cA:
3.2		 6dlzA-4h0cA:
19.63
6dlzD-4h0cA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4h0c PHOSPHOLIPASE/CARBOX
YLESTERASE
(Dyadobacter
fermentans) 		5 / 10 ILE A 126
SER A 105
GLY A 103
SER A 154
ASP A 159
 None
CIT  A 301 (-3.1A)
None
None
None
 1.14A 6dlzB-4h0cA:
3.1
6dlzC-4h0cA:
3.2		 6dlzB-4h0cA:
19.63
6dlzC-4h0cA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4h0c PHOSPHOLIPASE/CARBOX
YLESTERASE
(Dyadobacter
fermentans) 		5 / 10 SER A 154
ASP A 159
ILE A 126
SER A 105
GLY A 103
 None
None
None
CIT  A 301 (-3.1A)
None
 1.15A 6dm1A-4h0cA:
2.9
6dm1D-4h0cA:
3.2		 6dm1A-4h0cA:
19.63
6dm1D-4h0cA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4h0c PHOSPHOLIPASE/CARBOX
YLESTERASE
(Dyadobacter
fermentans) 		5 / 10 ILE A 126
SER A 105
GLY A 103
SER A 154
ASP A 159
 None
CIT  A 301 (-3.1A)
None
None
None
 1.15A 6dm1B-4h0cA:
2.9
6dm1C-4h0cA:
3.2		 6dm1B-4h0cA:
19.63
6dm1C-4h0cA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 4h0c PHOSPHOLIPASE/CARBOX
YLESTERASE
(Dyadobacter
fermentans) 		4 / 8 GLY A 130
LEU A 110
GLY A 107
GLU A 113
 CIT  A 301 (-3.4A)
None
None
None
 0.81A 6mdqA-4h0cA:
undetectable		 6mdqA-4h0cA:
18.66