SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h0g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 4h0g 2D10 SCFV
(Mus
musculus) 		4 / 8 HIS A 178
TYR A 180
TYR A 193
SER A 235
 None
 0.76A 1i7zA-4h0gA:
20.2		 1i7zA-4h0gA:
65.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 4h0g 2D10 SCFV
(Mus
musculus) 		5 / 12 GLY A 208
SER A 233
HIS A 178
ASN A 197
SER A 235
 None
 1.27A 4pooB-4h0gA:
undetectable		 4pooB-4h0gA:
21.67