SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h0s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 4h0s BASIC PHOSPHOLIPASE
A2 HOMOLOG CTS-R6
(Trimeresurus
stejnegeri) 		4 / 7 GLY A  30
HIS A  48
TYR A  52
LYS A  69
 None
 1.00A 1th6A-4h0sA:
20.6		 1th6A-4h0sA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4h0s BASIC PHOSPHOLIPASE
A2 HOMOLOG CTS-R6
(Trimeresurus
stejnegeri) 		4 / 7 GLY A  30
HIS A  48
TYR A  52
LYS A  69
 None
 1.01A 2armA-4h0sA:
20.5		 2armA-4h0sA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 4h0s BASIC PHOSPHOLIPASE
A2 HOMOLOG CTS-R6
(Trimeresurus
stejnegeri) 		5 / 11 ARG A   6
ILE A   9
TYR A  25
GLY A  30
PHE A 106
 None
 0.88A 2azyA-4h0sA:
14.6		 2azyA-4h0sA:
34.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4h0s BASIC PHOSPHOLIPASE
A2 HOMOLOG CTS-R6
(Trimeresurus
stejnegeri) 		5 / 10 LEU A   2
ILE A  19
GLY A  30
HIS A  48
PHE A 106
 None
 0.68A 2b17A-4h0sA:
20.5		 2b17A-4h0sA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4h0s BASIC PHOSPHOLIPASE
A2 HOMOLOG CTS-R6
(Trimeresurus
stejnegeri) 		5 / 5 LEU A   2
ILE A  19
SER A  23
GLY A  30
HIS A  48
 None
 0.77A 2otfA-4h0sA:
20.4		 2otfA-4h0sA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4h0s BASIC PHOSPHOLIPASE
A2 HOMOLOG CTS-R6
(Trimeresurus
stejnegeri) 		4 / 5 LEU A   2
ILE A  19
SER A  23
LYS A  69
 None
 1.13A 2othA-4h0sA:
20.4		 2othA-4h0sA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OUB_A_2TNA134_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4h0s BASIC PHOSPHOLIPASE
A2 HOMOLOG CTS-R6
(Trimeresurus
stejnegeri) 		4 / 4 LEU A   2
ILE A  19
HIS A  48
LYS A  69
 None
 1.18A 2oubA-4h0sA:
20.3		 2oubA-4h0sA:
50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 4h0s BASIC PHOSPHOLIPASE
A2 HOMOLOG CTS-R6
(Trimeresurus
stejnegeri) 		5 / 11 LEU A 110
ASP A  39
ASN A 117
GLY A  26
ASP A  42
 None
 1.25A 3sfuC-4h0sA:
undetectable		 3sfuC-4h0sA:
14.69