SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h0u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 HIS A  54
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
VAL A 264
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
None
 0.93A 1axwA-4h0uA:
38.7		 1axwA-4h0uA:
63.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 HIS A  54
LEU A 146
ASP A 172
LEU A 175
GLY A 176
PHE A 179
VAL A 264
 None
None
None
None
UMP  A 301 (-3.6A)
None
None
 1.19A 1axwA-4h0uA:
38.7		 1axwA-4h0uA:
63.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 LYS A  51
HIS A  54
ASP A 172
LEU A 175
GLY A 176
TYR A 212
VAL A 264
 None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
None
 0.69A 1axwA-4h0uA:
38.7		 1axwA-4h0uA:
63.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 LYS A  51
HIS A  54
ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.75A 1axwA-4h0uA:
38.7		 1axwA-4h0uA:
63.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 LYS A  51
HIS A  54
ILE A  82
LEU A 146
ASP A 172
GLY A 176
 None
None
None
None
None
UMP  A 301 (-3.6A)
 0.95A 1axwA-4h0uA:
38.7		 1axwA-4h0uA:
63.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 LYS A  51
HIS A  54
LEU A 146
ASP A 172
LEU A 175
GLY A 176
VAL A 264
 None
None
None
None
None
UMP  A 301 (-3.6A)
None
 1.05A 1axwA-4h0uA:
38.7		 1axwA-4h0uA:
63.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 11 ASP A 172
GLY A 176
PHE A 179
TYR A 212
VAL A 264
 None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
None
 0.97A 1axwB-4h0uA:
38.9		 1axwB-4h0uA:
63.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LYS A  51
ASP A 172
LEU A 175
GLY A 176
TYR A 212
VAL A 264
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
None
 0.69A 1axwB-4h0uA:
38.9		 1axwB-4h0uA:
63.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LYS A  51
ILE A  82
ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.62A 1axwB-4h0uA:
38.9		 1axwB-4h0uA:
63.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 11 LEU A 146
ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.86A 1b02A-4h0uA:
33.1		 1b02A-4h0uA:
39.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_A_D16A414_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 GLU A  61
ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.60A 1hvyA-4h0uA:
36.6		 1hvyA-4h0uA:
47.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 GLU A  61
ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.62A 1hvyB-4h0uA:
36.5		 1hvyB-4h0uA:
47.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_C_D16C416_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 11 GLU A  61
ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.53A 1hvyC-4h0uA:
36.7		 1hvyC-4h0uA:
47.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 GLU A  61
ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.53A 1hvyD-4h0uA:
36.6		 1hvyD-4h0uA:
47.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 GLU A  61
ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.63A 1hvyD-4h0uA:
36.6		 1hvyD-4h0uA:
47.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_A_D16A315_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 GLU A  61
ILE A  82
TRP A  83
ASP A 172
GLY A 176
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.53A 1i00A-4h0uA:
34.9		 1i00A-4h0uA:
47.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ILE A  82
ASP A 172
GLY A 176
ASN A 180
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-3.0A)
UMP  A 301 (-4.5A)
 0.41A 1i00B-4h0uA:
21.2		 1i00B-4h0uA:
47.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 11 ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.63A 1ju6A-4h0uA:
35.9		 1ju6A-4h0uA:
45.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_B_LYAB315_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 LYS A  51
ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.40A 1ju6B-4h0uA:
35.9		 1ju6B-4h0uA:
45.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.63A 1ju6C-4h0uA:
35.9		 1ju6C-4h0uA:
45.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 11 LYS A  51
ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.40A 1ju6D-4h0uA:
35.9		 1ju6D-4h0uA:
45.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_A_LYAA315_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LYS A  51
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.64A 1jujA-4h0uA:
35.5		 1jujA-4h0uA:
45.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_B_LYAB315_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LYS A  51
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.64A 1jujB-4h0uA:
35.5		 1jujB-4h0uA:
45.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LYS A  51
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.63A 1jujC-4h0uA:
35.5		 1jujC-4h0uA:
45.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LYS A  51
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.64A 1jujD-4h0uA:
35.5		 1jujD-4h0uA:
45.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 8 ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.74A 1rtsA-4h0uA:
35.4		 1rtsA-4h0uA:
46.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 7 ARG A  81
ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.53A 1rtsB-4h0uA:
36.1		 1rtsB-4h0uA:
46.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.57A 1rtsB-4h0uA:
36.1		 1rtsB-4h0uA:
46.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A  54
LEU A 175
GLY A 176
PHE A 179
TYR A 212
VAL A 264
 None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
None
 0.88A 1tlsA-4h0uA:
38.7		 1tlsA-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A  54
SER A  57
ILE A  82
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.88A 1tlsA-4h0uA:
38.7		 1tlsA-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A  54
SER A  57
ILE A  82
LEU A 146
GLY A 176
 None
None
None
None
UMP  A 301 (-3.6A)
 0.83A 1tlsA-4h0uA:
38.7		 1tlsA-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A  54
SER A  57
ILE A  82
TRP A  83
LEU A 146
 None
 0.70A 1tlsA-4h0uA:
38.7		 1tlsA-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A  54
SER A  57
LEU A 146
GLY A 176
PHE A 179
 None
None
None
UMP  A 301 (-3.6A)
None
 0.94A 1tlsA-4h0uA:
38.7		 1tlsA-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A  54
SER A  57
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.84A 1tlsA-4h0uA:
38.7		 1tlsA-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A  54
LEU A 146
LEU A 175
GLY A 176
PHE A 179
VAL A 264
 None
None
None
UMP  A 301 (-3.6A)
None
None
 1.40A 1tlsB-4h0uA:
38.7		 1tlsB-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A  54
LEU A 175
GLY A 176
PHE A 179
TYR A 212
VAL A 264
 None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
None
 1.07A 1tlsB-4h0uA:
38.7		 1tlsB-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A  54
SER A  57
ILE A  82
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.86A 1tlsB-4h0uA:
38.7		 1tlsB-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A  54
SER A  57
ILE A  82
LEU A 146
GLY A 176
 None
None
None
None
UMP  A 301 (-3.6A)
 0.86A 1tlsB-4h0uA:
38.7		 1tlsB-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A  54
SER A  57
ILE A  82
TRP A  83
LEU A 146
 None
 0.79A 1tlsB-4h0uA:
38.7		 1tlsB-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A  54
SER A  57
LEU A 146
LEU A 175
GLY A 176
 None
None
None
None
UMP  A 301 (-3.6A)
 1.04A 1tlsB-4h0uA:
38.7		 1tlsB-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A  54
SER A  57
LEU A 175
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.69A 1tlsB-4h0uA:
38.7		 1tlsB-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TSN_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A  54
LEU A 175
GLY A 176
PHE A 179
TYR A 212
VAL A 264
 None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
None
 0.94A 1tsnA-4h0uA:
38.6		 1tsnA-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TSN_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A  54
SER A  57
ILE A  82
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.83A 1tsnA-4h0uA:
38.6		 1tsnA-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TSN_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A  54
SER A  57
ILE A  82
TRP A  83
LEU A 146
GLY A 176
 None
None
None
None
None
UMP  A 301 (-3.6A)
 0.75A 1tsnA-4h0uA:
38.6		 1tsnA-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TSN_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A  54
SER A  57
LEU A 175
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.70A 1tsnA-4h0uA:
38.6		 1tsnA-4h0uA:
63.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 4 VAL A 199
LEU A  66
ILE A 115
LEU A 119
 None
 0.98A 2byoA-4h0uA:
undetectable		 2byoA-4h0uA:
23.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 SER A  57
GLU A  61
ASP A 172
GLY A 176
PHE A 179
TYR A 212
VAL A 264
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
None
 0.91A 2kceA-4h0uA:
38.8		 2kceA-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 SER A  57
GLU A  61
LEU A 146
GLY A 176
PHE A 179
 None
None
None
UMP  A 301 (-3.6A)
None
 1.07A 2kceA-4h0uA:
38.8		 2kceA-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 SER A  57
ASP A 172
GLY A 176
TYR A 212
VAL A 264
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
None
 0.84A 2kceB-4h0uA:
38.9		 2kceB-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 SER A  57
ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.72A 2kceB-4h0uA:
38.9		 2kceB-4h0uA:
63.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.72A 2tsrA-4h0uA:
35.7		 2tsrA-4h0uA:
46.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.47A 2tsrA-4h0uA:
35.7		 2tsrA-4h0uA:
46.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 GLU A  61
ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.79A 2tsrC-4h0uA:
35.4		 2tsrC-4h0uA:
46.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 GLU A  61
ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.51A 2tsrC-4h0uA:
35.4		 2tsrC-4h0uA:
46.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A 162
ASN A 236
VAL A 251
LEU A 186
PHE A  55
 None
 1.14A 2zzmA-4h0uA:
undetectable		 2zzmA-4h0uA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 SER A  57
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.93A 3k2hA-4h0uA:
35.9		 3k2hA-4h0uA:
27.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 SER A  57
GLU A  61
ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.91A 3k2hA-4h0uA:
35.9		 3k2hA-4h0uA:
27.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 SER A  57
GLU A  61
ILE A  82
TRP A  83
LEU A 146
 None
 0.69A 3k2hA-4h0uA:
35.9		 3k2hA-4h0uA:
27.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 SER A  57
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.94A 3k2hB-4h0uA:
36.1		 3k2hB-4h0uA:
27.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 SER A  57
GLU A  61
ASP A 172
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.82A 3k2hB-4h0uA:
36.1		 3k2hB-4h0uA:
27.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 SER A  57
GLU A  61
ILE A  82
TRP A  83
LEU A 146
 None
 0.70A 3k2hB-4h0uA:
36.1		 3k2hB-4h0uA:
27.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 SER A  57
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.95A 3nrrA-4h0uA:
36.6		 3nrrA-4h0uA:
27.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 SER A  57
GLU A  61
ASP A 172
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.89A 3nrrA-4h0uA:
36.6		 3nrrA-4h0uA:
27.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 SER A  57
GLU A  61
ILE A  82
ASP A 172
TYR A 212
 None
None
None
None
UMP  A 301 (-4.5A)
 0.85A 3nrrA-4h0uA:
36.6		 3nrrA-4h0uA:
27.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 SER A  57
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.98A 3nrrB-4h0uA:
36.7		 3nrrB-4h0uA:
27.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 SER A  57
GLU A  61
ASP A 172
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.88A 3nrrB-4h0uA:
36.7		 3nrrB-4h0uA:
27.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 SER A  57
GLU A  61
ILE A  82
ASP A 172
TYR A 212
 None
None
None
None
UMP  A 301 (-4.5A)
 0.83A 3nrrB-4h0uA:
36.7		 3nrrB-4h0uA:
27.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 8 ARG A 123
GLN A 194
LEU A 235
TYR A 244
 None
 0.70A 3qj7A-4h0uA:
41.1
3qj7D-4h0uA:
40.9		 3qj7A-4h0uA:
72.18
3qj7D-4h0uA:
72.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A  11
TYR A   7
ILE A 181
ILE A  37
ALA A 171
 None
None
None
None
UMP  A 301 ( 4.9A)
 1.09A 3uj7A-4h0uA:
undetectable		 3uj7A-4h0uA:
22.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A 150
LEU A 175
GLY A 176
PHE A 179
ASN A 180
TYR A 212
 UMP  A 301 (-4.2A)
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-3.0A)
UMP  A 301 (-4.5A)
 0.50A 3uwlB-4h0uA:
38.0		 3uwlB-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 ILE A  82
TRP A  83
LEU A 146
HIS A 150
GLY A 176
ASN A 180
 None
None
None
UMP  A 301 (-4.2A)
UMP  A 301 (-3.6A)
UMP  A 301 (-3.0A)
 0.73A 3uwlB-4h0uA:
38.0		 3uwlB-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 LEU A 146
HIS A 150
LEU A 175
GLY A 176
PHE A 179
ASN A 180
 None
UMP  A 301 (-4.2A)
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-3.0A)
 0.54A 3uwlB-4h0uA:
38.0		 3uwlB-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 TRP A  83
LEU A 146
HIS A 150
GLY A 176
PHE A 179
ASN A 180
 None
None
UMP  A 301 (-4.2A)
UMP  A 301 (-3.6A)
None
UMP  A 301 (-3.0A)
 0.71A 3uwlB-4h0uA:
38.0		 3uwlB-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A 150
LEU A 175
GLY A 176
PHE A 179
ASN A 180
TYR A 212
 UMP  A 301 (-4.2A)
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-3.0A)
UMP  A 301 (-4.5A)
 0.51A 3uwlD-4h0uA:
36.1		 3uwlD-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 LEU A 146
HIS A 150
LEU A 175
GLY A 176
PHE A 179
ASN A 180
 None
UMP  A 301 (-4.2A)
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-3.0A)
 0.50A 3uwlD-4h0uA:
36.1		 3uwlD-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 TRP A  83
LEU A 146
HIS A 150
GLY A 176
PHE A 179
ASN A 180
 None
None
UMP  A 301 (-4.2A)
UMP  A 301 (-3.6A)
None
UMP  A 301 (-3.0A)
 0.76A 3uwlD-4h0uA:
36.1		 3uwlD-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 ILE A  82
ASP A 172
GLY A 176
ASN A 180
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-3.0A)
UMP  A 301 (-4.5A)
 0.70A 4eb4A-4h0uA:
35.8		 4eb4A-4h0uA:
46.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ILE A  82
ASP A 172
GLY A 176
ASN A 180
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-3.0A)
UMP  A 301 (-4.5A)
 0.52A 4eb4C-4h0uA:
35.4		 4eb4C-4h0uA:
46.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 ILE A  82
ASP A 172
GLY A 176
ASN A 180
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-3.0A)
UMP  A 301 (-4.5A)
 0.56A 4eb4D-4h0uA:
36.2		 4eb4D-4h0uA:
46.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 HIS A  54
SER A  57
ILE A  82
LEU A 146
ASP A 172
GLY A 176
TYR A 212
 None
None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.82A 4fogA-4h0uA:
40.4		 4fogA-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 HIS A  54
SER A  57
ILE A  82
TRP A  83
LEU A 146
GLY A 176
TYR A 212
 None
None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.81A 4fogA-4h0uA:
40.4		 4fogA-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 LYS A  51
HIS A  54
LEU A 146
ASP A 172
GLY A 176
PHE A 179
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.88A 4fogA-4h0uA:
40.4		 4fogA-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 LYS A  51
HIS A  54
SER A  57
LEU A 146
ASP A 172
GLY A 176
TYR A 212
 None
None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.73A 4fogA-4h0uA:
40.4		 4fogA-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 LYS A  51
HIS A  54
SER A  57
TRP A  83
LEU A 146
GLY A 176
TYR A 212
 None
None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.77A 4fogA-4h0uA:
40.4		 4fogA-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 HIS A  54
LEU A 146
ASP A 172
GLY A 176
PHE A 179
TYR A 212
VAL A 264
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
None
 1.10A 4fogC-4h0uA:
40.5		 4fogC-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 HIS A  54
SER A  57
ILE A  82
TRP A  83
LEU A 146
GLY A 176
TYR A 212
 None
None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.88A 4fogC-4h0uA:
40.5		 4fogC-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 HIS A  54
SER A  57
ILE A  82
TRP A  83
TRP A  86
LEU A 146
GLY A 176
 None
None
None
None
None
None
UMP  A 301 (-3.6A)
 0.76A 4fogC-4h0uA:
40.5		 4fogC-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 HIS A  54
SER A  57
LEU A 146
ASP A 172
GLY A 176
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.89A 4fogC-4h0uA:
40.5		 4fogC-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 HIS A  54
TRP A  83
LEU A 146
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 1.02A 4fogC-4h0uA:
40.5		 4fogC-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 HIS A  54
TRP A  83
TRP A  86
LEU A 146
GLY A 176
PHE A 179
 None
None
None
None
UMP  A 301 (-3.6A)
None
 0.96A 4fogC-4h0uA:
40.5		 4fogC-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 11 ILE A  82
TRP A  83
TRP A  86
LEU A 146
GLY A 176
 None
None
None
None
UMP  A 301 (-3.6A)
 0.82A 4fogD-4h0uA:
40.5		 4fogD-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LYS A  51
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.55A 4fogD-4h0uA:
40.5		 4fogD-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LYS A  51
ILE A  82
ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.69A 4fogD-4h0uA:
40.5		 4fogD-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LYS A  51
ILE A  82
LEU A 146
ASP A 172
LEU A 175
GLY A 176
 None
None
None
None
None
UMP  A 301 (-3.6A)
 0.97A 4fogD-4h0uA:
40.5		 4fogD-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 11 LYS A  51
ILE A  82
TRP A  83
LEU A 146
GLY A 176
 None
None
None
None
UMP  A 301 (-3.6A)
 0.88A 4fogD-4h0uA:
40.5		 4fogD-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LYS A  51
LEU A 146
ASP A 172
LEU A 175
GLY A 176
PHE A 179
 None
None
None
None
UMP  A 301 (-3.6A)
None
 0.84A 4fogD-4h0uA:
40.5		 4fogD-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A  54
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.83A 4foxA-4h0uA:
40.5		 4foxA-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A  54
SER A  57
ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.69A 4foxA-4h0uA:
40.5		 4foxA-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 HIS A  54
SER A  57
GLU A  61
ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.72A 4foxA-4h0uA:
40.5		 4foxA-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 HIS A  54
SER A  57
GLU A  61
ILE A  82
TRP A  83
TRP A  86
LEU A 146
 None
 0.66A 4foxA-4h0uA:
40.5		 4foxA-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 HIS A  54
SER A  57
GLU A  61
ILE A  82
TRP A  86
LEU A 146
GLY A 176
 None
None
None
None
None
None
UMP  A 301 (-3.6A)
 0.78A 4foxA-4h0uA:
40.5		 4foxA-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A  54
TRP A  86
LEU A 146
GLY A 176
PHE A 179
 None
None
None
UMP  A 301 (-3.6A)
None
 0.97A 4foxA-4h0uA:
40.5		 4foxA-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 SER A  57
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.92A 4foxB-4h0uA:
40.6		 4foxB-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 SER A  57
GLU A  61
ASP A 172
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.78A 4foxB-4h0uA:
40.6		 4foxB-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 SER A  57
GLU A  61
ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.68A 4foxB-4h0uA:
40.6		 4foxB-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 SER A  57
GLU A  61
ILE A  82
LEU A 146
ASP A 172
GLY A 176
 None
None
None
None
None
UMP  A 301 (-3.6A)
 0.90A 4foxB-4h0uA:
40.6		 4foxB-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 SER A  57
GLU A  61
ILE A  82
TRP A  83
LEU A 146
 None
 0.61A 4foxB-4h0uA:
40.6		 4foxB-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 SER A  57
GLU A  61
LEU A 146
ASP A 172
GLY A 176
PHE A 179
 None
None
None
None
UMP  A 301 (-3.6A)
None
 1.04A 4foxB-4h0uA:
40.6		 4foxB-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 HIS A  54
SER A  57
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.86A 4foxC-4h0uA:
40.1		 4foxC-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 HIS A  54
SER A  57
GLU A  61
ASP A 172
GLY A 176
PHE A 179
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.81A 4foxC-4h0uA:
40.1		 4foxC-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 HIS A  54
SER A  57
GLU A  61
TRP A  83
TRP A  86
LEU A 146
 None
 0.66A 4foxC-4h0uA:
40.1		 4foxC-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 HIS A  54
SER A  57
GLU A  61
TRP A  86
LEU A 146
GLY A 176
PHE A 179
 None
None
None
None
None
UMP  A 301 (-3.6A)
None
 1.04A 4foxC-4h0uA:
40.1		 4foxC-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
VAL A 264
 None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
None
 0.69A 4foxD-4h0uA:
40.4		 4foxD-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 GLU A  61
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.78A 4foxD-4h0uA:
40.4		 4foxD-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 SER A  57
GLU A  61
ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.74A 4foxD-4h0uA:
40.4		 4foxD-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 SER A  57
GLU A  61
ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.72A 4foxD-4h0uA:
40.4		 4foxD-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A  54
SER A  57
GLU A  61
ILE A  82
TRP A  83
TRP A  86
 None
 0.72A 4foxE-4h0uA:
40.5		 4foxE-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		8 / 12 LYS A  51
HIS A  54
SER A  57
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.78A 4foxE-4h0uA:
40.5		 4foxE-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		8 / 12 LYS A  51
HIS A  54
SER A  57
GLU A  61
ASP A 172
GLY A 176
PHE A 179
TYR A 212
 None
None
None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.78A 4foxE-4h0uA:
40.5		 4foxE-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		8 / 12 LYS A  51
HIS A  54
SER A  57
GLU A  61
ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.74A 4foxE-4h0uA:
40.5		 4foxE-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		8 / 12 LYS A  51
HIS A  54
SER A  57
GLU A  61
ILE A  82
TRP A  86
ASP A 172
GLY A 176
 None
None
None
None
None
None
None
UMP  A 301 (-3.6A)
 0.92A 4foxE-4h0uA:
40.5		 4foxE-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		8 / 12 LYS A  51
HIS A  54
SER A  57
GLU A  61
TRP A  86
ASP A 172
GLY A 176
PHE A 179
 None
None
None
None
None
None
UMP  A 301 (-3.6A)
None
 1.00A 4foxE-4h0uA:
40.5		 4foxE-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 HIS A  54
GLU A  61
ASP A 172
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.83A 4foxF-4h0uA:
40.2		 4foxF-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 HIS A  54
GLU A  61
ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.79A 4foxF-4h0uA:
40.2		 4foxF-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 HIS A  54
GLU A  61
ILE A  82
TRP A  83
TRP A  86
LEU A 146
 None
 0.71A 4foxF-4h0uA:
40.2		 4foxF-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 HIS A  54
GLU A  61
ILE A  82
TRP A  86
LEU A 146
GLY A 176
 None
None
None
None
None
UMP  A 301 (-3.6A)
 0.95A 4foxF-4h0uA:
40.2		 4foxF-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 HIS A  54
GLU A  61
TRP A  86
LEU A 146
GLY A 176
PHE A 179
 None
None
None
None
UMP  A 301 (-3.6A)
None
 1.11A 4foxF-4h0uA:
40.2		 4foxF-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		8 / 12 HIS A  54
SER A  57
GLU A  61
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.85A 4foxG-4h0uA:
40.1		 4foxG-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 HIS A  54
SER A  57
GLU A  61
ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.73A 4foxG-4h0uA:
40.1		 4foxG-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A  54
SER A  57
GLU A  61
ILE A  82
LEU A 146
GLY A 176
 None
None
None
None
None
UMP  A 301 (-3.6A)
 0.84A 4foxG-4h0uA:
40.1		 4foxG-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A  54
SER A  57
GLU A  61
ILE A  82
TRP A  83
LEU A 146
 None
 0.66A 4foxG-4h0uA:
40.1		 4foxG-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A  54
SER A  57
GLU A  61
LEU A 146
GLY A 176
PHE A 179
 None
None
None
None
UMP  A 301 (-3.6A)
None
 1.01A 4foxG-4h0uA:
40.1		 4foxG-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_H_D16H301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 11 HIS A  54
ASP A 172
GLY A 176
PHE A 179
TYR A 212
 None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.79A 4foxH-4h0uA:
39.9		 4foxH-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_H_D16H301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 HIS A  54
SER A  57
GLU A  61
ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.87A 4foxH-4h0uA:
39.9		 4foxH-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_H_D16H301_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 11 HIS A  54
SER A  57
GLU A  61
ILE A  82
TRP A  83
 None
 0.60A 4foxH-4h0uA:
39.9		 4foxH-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 HIS A  54
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
VAL A 264
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
None
 0.85A 4fqsA-4h0uA:
40.3		 4fqsA-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A  54
GLU A  61
ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.64A 4fqsA-4h0uA:
40.3		 4fqsA-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A  54
GLU A  61
ILE A  82
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.89A 4fqsA-4h0uA:
40.3		 4fqsA-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 HIS A  54
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
VAL A 264
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
None
 0.82A 4fqsB-4h0uA:
40.2		 4fqsB-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A  54
GLU A  61
ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.63A 4fqsB-4h0uA:
40.2		 4fqsB-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A  54
GLU A  61
ILE A  82
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.90A 4fqsB-4h0uA:
40.2		 4fqsB-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A  54
GLU A  61
ILE A  82
TRP A  83
GLY A 176
 None
None
None
None
UMP  A 301 (-3.6A)
 0.90A 4fqsB-4h0uA:
40.2		 4fqsB-4h0uA:
72.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.80A 4iqqB-4h0uA:
34.9		 4iqqB-4h0uA:
42.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.48A 4iqqB-4h0uA:
34.9		 4iqqB-4h0uA:
42.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.69A 4iqqC-4h0uA:
35.2		 4iqqC-4h0uA:
42.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.41A 4iqqC-4h0uA:
35.2		 4iqqC-4h0uA:
42.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 LYS A  51
VAL A  53
CYH A 149
LEU A 175
TYR A 212
 None
None
UMP  A 301 (-3.2A)
None
UMP  A 301 (-4.5A)
 0.83A 5fctB-4h0uA:
36.4		 5fctB-4h0uA:
46.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H3A_A_D16A401_1
(ORF70)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.36A 5h3aA-4h0uA:
21.6		 5h3aA-4h0uA:
50.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H3A_B_D16B401_1
(ORF70)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.74A 5h3aB-4h0uA:
36.3		 5h3aB-4h0uA:
50.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H3A_B_D16B401_1
(ORF70)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.43A 5h3aB-4h0uA:
36.3		 5h3aB-4h0uA:
50.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.42A 5j7wC-4h0uA:
37.8		 5j7wC-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 GLU A  61
ASP A 172
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.70A 5j7wD-4h0uA:
37.5		 5j7wD-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 GLU A  61
ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.81A 5j7wD-4h0uA:
37.5		 5j7wD-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 GLU A  61
ILE A  82
TRP A  83
LEU A 146
GLY A 176
 None
None
None
None
UMP  A 301 (-3.6A)
 0.75A 5j7wD-4h0uA:
37.5		 5j7wD-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 GLU A  61
LEU A 146
LEU A 175
GLY A 176
PHE A 179
 None
None
None
UMP  A 301 (-3.6A)
None
 0.87A 5j7wD-4h0uA:
37.5		 5j7wD-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 GLU A  61
TRP A  83
LEU A 146
GLY A 176
PHE A 179
 None
None
None
UMP  A 301 (-3.6A)
None
 0.92A 5j7wD-4h0uA:
37.5		 5j7wD-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.80A 5nooA-4h0uA:
35.5		 5nooA-4h0uA:
42.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.48A 5nooA-4h0uA:
35.5		 5nooA-4h0uA:
42.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.80A 5nooB-4h0uA:
35.2		 5nooB-4h0uA:
42.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.40A 5nooB-4h0uA:
35.2		 5nooB-4h0uA:
42.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 6 ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.79A 5nooC-4h0uA:
35.5		 5nooC-4h0uA:
42.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 GLU A  61
ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.78A 5x5qB-4h0uA:
36.5		 5x5qB-4h0uA:
47.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 GLU A  61
ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.63A 5x5qB-4h0uA:
36.5		 5x5qB-4h0uA:
47.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.69A 5x5qC-4h0uA:
35.5		 5x5qC-4h0uA:
47.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.49A 5x5qC-4h0uA:
35.5		 5x5qC-4h0uA:
47.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 8 ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.69A 5x5qD-4h0uA:
35.3		 5x5qD-4h0uA:
47.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 8 ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.55A 5x5qD-4h0uA:
35.3		 5x5qD-4h0uA:
47.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 6 ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.68A 5x5qE-4h0uA:
35.4		 5x5qE-4h0uA:
47.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 6 ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.53A 5x5qE-4h0uA:
35.4		 5x5qE-4h0uA:
47.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 8 ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.69A 5x5qF-4h0uA:
35.0		 5x5qF-4h0uA:
47.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		4 / 8 ILE A  82
ASP A 172
GLY A 176
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.57A 5x5qF-4h0uA:
35.0		 5x5qF-4h0uA:
47.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 ILE A  82
ASP A 172
LEU A 175
GLY A 176
ASN A 180
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-3.0A)
UMP  A 301 (-4.5A)
 0.51A 5x66A-4h0uA:
36.8
5x66B-4h0uA:
36.9		 5x66A-4h0uA:
47.59
5x66B-4h0uA:
47.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ILE A  82
ASP A 172
LEU A 175
GLY A 176
ASN A 180
TYR A 212
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-3.0A)
UMP  A 301 (-4.5A)
 0.61A 5x66C-4h0uA:
37.0		 5x66C-4h0uA:
47.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 ILE A  82
ASP A 172
GLY A 176
ASN A 180
TYR A 212
 None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-3.0A)
UMP  A 301 (-4.5A)
 0.55A 5x66D-4h0uA:
36.8		 5x66D-4h0uA:
47.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_F_MTXF402_1
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 LYS A  51
ILE A  82
ASP A 172
LEU A 175
GLY A 176
TYR A 212
 None
None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-4.5A)
 0.57A 5x66F-4h0uA:
36.7		 5x66F-4h0uA:
47.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		3 / 3 VAL A  72
ALA A  87
GLN A  76
 None
 0.38A 6gb9A-4h0uA:
undetectable		 6gb9A-4h0uA:
21.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 ILE A  82
TRP A  83
LEU A 146
GLY A 176
ASN A 180
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-3.0A)
 0.77A 6qxsB-4h0uA:
36.1		 6qxsB-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A 146
LEU A 175
GLY A 176
PHE A 179
ASN A 180
 None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-3.0A)
 0.58A 6qxsB-4h0uA:
36.1		 6qxsB-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A 175
GLY A 176
PHE A 179
ASN A 180
TYR A 212
 None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-3.0A)
UMP  A 301 (-4.5A)
 0.51A 6qxsB-4h0uA:
36.1		 6qxsB-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 TRP A  83
LEU A 146
GLY A 176
PHE A 179
ASN A 180
 None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-3.0A)
 0.84A 6qxsB-4h0uA:
36.1		 6qxsB-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_D_FOZD403_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 ILE A  82
TRP A  83
LEU A 146
GLY A 176
ASN A 180
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-3.0A)
 0.71A 6qxsD-4h0uA:
36.0		 6qxsD-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QYA_B_FOZB401_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A 150
LEU A 175
GLY A 176
PHE A 179
TYR A 212
 UMP  A 301 (-4.2A)
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-4.5A)
 0.49A 6qyaB-4h0uA:
35.6		 6qyaB-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QYA_B_FOZB401_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A 146
HIS A 150
LEU A 175
GLY A 176
PHE A 179
 None
UMP  A 301 (-4.2A)
None
UMP  A 301 (-3.6A)
None
 0.56A 6qyaB-4h0uA:
35.6		 6qyaB-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 HIS A 150
LEU A 175
GLY A 176
PHE A 179
ASN A 180
TYR A 212
 UMP  A 301 (-4.2A)
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-3.0A)
UMP  A 301 (-4.5A)
 0.46A 6qyaD-4h0uA:
35.6		 6qyaD-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 ILE A  82
TRP A  83
LEU A 146
HIS A 150
ASN A 180
 None
None
None
UMP  A 301 (-4.2A)
UMP  A 301 (-3.0A)
 0.58A 6qyaD-4h0uA:
35.6		 6qyaD-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 LEU A 146
HIS A 150
LEU A 175
GLY A 176
PHE A 179
ASN A 180
 None
UMP  A 301 (-4.2A)
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-3.0A)
 0.53A 6qyaD-4h0uA:
35.6		 6qyaD-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 TRP A  83
LEU A 146
HIS A 150
GLY A 176
ASN A 180
 None
None
UMP  A 301 (-4.2A)
UMP  A 301 (-3.6A)
UMP  A 301 (-3.0A)
 0.59A 6qyaD-4h0uA:
35.6		 6qyaD-4h0uA:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_A_FFOA403_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 ASP A 172
LEU A 175
GLY A 176
PHE A 179
ASN A 180
TYR A 212
 None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-3.0A)
UMP  A 301 (-4.5A)
 0.58A 6r2eA-4h0uA:
36.1		 6r2eA-4h0uA:
43.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_E_FFOE403_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 ILE A  82
TRP A  83
TYR A  97
LEU A 146
ASN A 180
 None
None
None
None
UMP  A 301 (-3.0A)
 0.71A 6r2eE-4h0uA:
36.1		 6r2eE-4h0uA:
43.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_E_FFOE403_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 TYR A  97
LEU A 146
LEU A 175
GLY A 176
PHE A 179
ASN A 180
 None
None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-3.0A)
 0.86A 6r2eE-4h0uA:
36.1		 6r2eE-4h0uA:
43.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_G_FFOG403_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 11 ASP A 172
LEU A 175
GLY A 176
PHE A 179
ASN A 180
 None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-3.0A)
 0.55A 6r2eG-4h0uA:
36.1		 6r2eG-4h0uA:
43.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_G_FFOG403_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 11 LEU A 146
LEU A 175
GLY A 176
PHE A 179
ASN A 180
 None
None
UMP  A 301 (-3.6A)
None
UMP  A 301 (-3.0A)
 0.91A 6r2eG-4h0uA:
36.1		 6r2eG-4h0uA:
43.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_H_FFOH403_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 ILE A  82
TRP A  83
TYR A  97
LEU A 146
ASN A 180
 None
None
None
None
UMP  A 301 (-3.0A)
 0.79A 6r2eH-4h0uA:
36.0		 6r2eH-4h0uA:
43.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_H_FFOH403_0
(THYMIDYLATE SYNTHASE)		 4h0u THYMIDYLATE SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 TRP A  83
TYR A  97
LEU A 146
GLY A 176
ASN A 180
 None
None
None
UMP  A 301 (-3.6A)
UMP  A 301 (-3.0A)
 0.94A 6r2eH-4h0uA:
36.0		 6r2eH-4h0uA:
43.38