SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h17'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 4h17 HYDROLASE,
ISOCHORISMATASE
FAMILY
(Pseudomonas
putida) 		4 / 5 LEU A 113
ILE A  66
LEU A  25
SER A  24
 None
 0.72A 2byoA-4h17A:
undetectable		 2byoA-4h17A:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_M_CLMM221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4h17 HYDROLASE,
ISOCHORISMATASE
FAMILY
(Pseudomonas
putida) 		5 / 10 SER A 134
VAL A  68
VAL A 136
PHE A  78
HIS A  70
 SO4  A 201 (-2.7A)
None
None
SO4  A 203 (-4.2A)
SO4  A 201 ( 3.8A)
 1.43A 3u9fM-4h17A:
0.0
3u9fN-4h17A:
0.0		 3u9fM-4h17A:
22.41
3u9fN-4h17A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 4h17 HYDROLASE,
ISOCHORISMATASE
FAMILY
(Pseudomonas
putida) 		5 / 9 ALA A  47
ALA A  30
ILE A  28
GLY A 129
ILE A  27
 None
 1.05A 4eatB-4h17A:
4.2		 4eatB-4h17A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4h17 HYDROLASE,
ISOCHORISMATASE
FAMILY
(Pseudomonas
putida) 		4 / 5 SER A 157
ALA A 156
HIS A 175
LEU A 152
 None
None
EDO  A 206 ( 4.1A)
None
 1.14A 5dzkb-4h17A:
undetectable
5dzkp-4h17A:
undetectable		 5dzkb-4h17A:
24.27
5dzkp-4h17A:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4h17 HYDROLASE,
ISOCHORISMATASE
FAMILY
(Pseudomonas
putida) 		4 / 5 SER A 157
ALA A 156
HIS A 175
LEU A 152
 None
None
EDO  A 206 ( 4.1A)
None
 1.16A 5dzkc-4h17A:
undetectable
5dzkq-4h17A:
undetectable		 5dzkc-4h17A:
24.27
5dzkq-4h17A:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4h17 HYDROLASE,
ISOCHORISMATASE
FAMILY
(Pseudomonas
putida) 		4 / 7 SER A 157
ALA A 156
HIS A 175
LEU A 152
 None
None
EDO  A 206 ( 4.1A)
None
 1.11A 5dzkD-4h17A:
undetectable
5dzkR-4h17A:
undetectable		 5dzkD-4h17A:
24.27
5dzkR-4h17A:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4h17 HYDROLASE,
ISOCHORISMATASE
FAMILY
(Pseudomonas
putida) 		4 / 5 SER A 157
ALA A 156
HIS A 175
LEU A 152
 None
None
EDO  A 206 ( 4.1A)
None
 1.05A 5dzkf-4h17A:
undetectable
5dzkt-4h17A:
undetectable		 5dzkf-4h17A:
24.27
5dzkt-4h17A:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4h17 HYDROLASE,
ISOCHORISMATASE
FAMILY
(Pseudomonas
putida) 		4 / 6 SER A 157
ALA A 156
HIS A 175
LEU A 152
 None
None
EDO  A 206 ( 4.1A)
None
 1.12A 5dzkg-4h17A:
undetectable
5dzku-4h17A:
undetectable		 5dzkg-4h17A:
24.27
5dzku-4h17A:
3.57