SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h19'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		3 / 3 ALA A  53
VAL A  32
TRP A  30
 None
 0.87A 1bdwA-4h19A:
undetectable
1bdwB-4h19A:
undetectable		 1bdwA-4h19A:
6.44
1bdwB-4h19A:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		4 / 4 THR A 103
LEU A 107
VAL A 110
LEU A 114
 CL  A 403 (-3.1A)
None
None
None
 0.51A 1fbmD-4h19A:
undetectable		 1fbmD-4h19A:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 11 ASP A 144
PHE A 168
VAL A 342
ILE A 340
ILE A 332
 None
None
None
None
CL  A 404 (-4.3A)
 1.33A 1fkfA-4h19A:
undetectable		 1fkfA-4h19A:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 11 ASP A 144
PHE A 168
VAL A 342
ILE A 340
ILE A 332
 None
None
None
None
CL  A 404 (-4.3A)
 1.32A 1fkjA-4h19A:
undetectable		 1fkjA-4h19A:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		3 / 3 TRP A 115
VAL A 110
TRP A  85
 None
 1.39A 1gmkC-4h19A:
undetectable
1gmkD-4h19A:
undetectable		 1gmkC-4h19A:
6.44
1gmkD-4h19A:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		4 / 4 THR A 103
LEU A 107
VAL A 110
LEU A 114
 CL  A 403 (-3.1A)
None
None
None
 0.96A 1mz9D-4h19A:
undetectable		 1mz9D-4h19A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 10 ASP A  58
GLY A  50
GLY A  31
ILE A  65
ALA A 109
 None
 0.99A 1x7pA-4h19A:
undetectable
1x7pB-4h19A:
undetectable		 1x7pA-4h19A:
23.29
1x7pB-4h19A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 12 GLY A  45
VAL A   6
ALA A  35
ASP A 116
ALA A 113
 None
 1.42A 2avdB-4h19A:
undetectable		 2avdB-4h19A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 11 ASP A 144
PHE A 168
VAL A 342
ILE A 340
ILE A 332
 None
None
None
None
CL  A 404 (-4.3A)
 1.31A 2fkeA-4h19A:
undetectable		 2fkeA-4h19A:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 12 LEU A 130
VAL A 279
HIS A 313
ALA A 113
VAL A 312
 None
 1.44A 2g70A-4h19A:
undetectable		 2g70A-4h19A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 12 LEU A 130
VAL A 279
HIS A 313
ALA A 113
VAL A 312
 None
 1.41A 2g72A-4h19A:
undetectable		 2g72A-4h19A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		3 / 3 LYS A 333
TYR A 328
PRO A 330
 None
None
CL  A 404 (-4.7A)
 1.43A 2j9cC-4h19A:
undetectable		 2j9cC-4h19A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 12 HIS A  25
THR A  24
GLU A 230
ASP A 203
ASP A 278
 0YR  A 410 (-3.8A)
None
MG  A 405 ( 4.8A)
MG  A 405 ( 2.6A)
None
 1.43A 2xinC-4h19A:
4.9		 2xinC-4h19A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 12 HIS A  25
THR A  24
GLU A 230
ASP A 203
ASP A 278
 0YR  A 410 (-3.8A)
None
MG  A 405 ( 4.8A)
MG  A 405 ( 2.6A)
None
 1.43A 2xinD-4h19A:
4.0		 2xinD-4h19A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 10 ARG A  99
ARG A  90
GLY A 101
THR A 280
THR A  49
 None
GOL  A 409 (-4.0A)
CL  A 403 ( 4.0A)
None
None
 1.50A 3abmG-4h19A:
undetectable
3abmN-4h19A:
undetectable
3abmO-4h19A:
undetectable		 3abmG-4h19A:
13.11
3abmN-4h19A:
21.11
3abmO-4h19A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		4 / 4 LEU A 232
PRO A 231
LEU A 243
ARG A 245
 None
 1.29A 3hcoA-4h19A:
undetectable		 3hcoA-4h19A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		3 / 3 SER A  17
ASP A 144
ASN A 142
 None
 0.98A 3lsfB-4h19A:
undetectable
3lsfE-4h19A:
undetectable		 3lsfB-4h19A:
23.06
3lsfE-4h19A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		3 / 3 ASP A 144
ASN A 142
SER A  17
 None
 0.96A 3lsfB-4h19A:
undetectable
3lsfE-4h19A:
undetectable		 3lsfB-4h19A:
23.06
3lsfE-4h19A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		3 / 3 ASP A 144
ASN A 142
SER A  17
 None
 0.78A 3lslA-4h19A:
undetectable
3lslD-4h19A:
undetectable		 3lslA-4h19A:
23.06
3lslD-4h19A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		3 / 3 SER A  17
ASP A 144
ASN A 142
 None
 0.70A 3lslA-4h19A:
undetectable
3lslD-4h19A:
undetectable		 3lslA-4h19A:
23.06
3lslD-4h19A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		4 / 4 GLY A 254
GLU A 230
ASP A 235
ASP A 278
 None
MG  A 405 ( 4.8A)
None
None
 0.96A 3mb5A-4h19A:
undetectable		 3mb5A-4h19A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 11 ASP A 144
PHE A 168
VAL A 342
ILE A 340
ILE A 332
 None
None
None
None
CL  A 404 (-4.3A)
 1.27A 4drjA-4h19A:
undetectable		 4drjA-4h19A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 10 ASP A 144
PHE A 168
VAL A 342
ILE A 340
ILE A 332
 None
None
None
None
CL  A 404 (-4.3A)
 1.35A 4qt2A-4h19A:
undetectable		 4qt2A-4h19A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 10 ASP A 144
PHE A 168
VAL A 342
ILE A 340
ILE A 332
 None
None
None
None
CL  A 404 (-4.3A)
 1.37A 4qt3A-4h19A:
undetectable		 4qt3A-4h19A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		4 / 7 ALA A 136
THR A 135
TYR A 318
VAL A 346
 None
GOL  A 407 (-3.6A)
None
None
 1.12A 5ecnA-4h19A:
0.0		 5ecnA-4h19A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		4 / 8 LEU A 326
LEU A 316
THR A 280
GLN A 256
 None
 1.13A 5hbsA-4h19A:
0.2		 5hbsA-4h19A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 12 ASP A 144
PHE A 168
VAL A 342
ILE A 340
ILE A 332
 None
None
None
None
CL  A 404 (-4.3A)
 1.19A 5hkgA-4h19A:
undetectable		 5hkgA-4h19A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 10 ARG A  99
ARG A  90
GLY A 101
THR A 280
THR A  49
 None
GOL  A 409 (-4.0A)
CL  A 403 ( 4.0A)
None
None
 1.47A 5iy5G-4h19A:
undetectable
5iy5N-4h19A:
0.0
5iy5O-4h19A:
undetectable		 5iy5G-4h19A:
13.15
5iy5N-4h19A:
21.11
5iy5O-4h19A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_T_CHDT103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 10 GLY A 101
THR A 280
THR A  49
ARG A  99
ARG A  90
 CL  A 403 ( 4.0A)
None
None
None
GOL  A 409 (-4.0A)
 1.43A 5iy5A-4h19A:
undetectable
5iy5B-4h19A:
undetectable
5iy5T-4h19A:
undetectable		 5iy5A-4h19A:
21.11
5iy5B-4h19A:
21.39
5iy5T-4h19A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 11 ARG A  99
ARG A  90
GLY A 101
THR A 280
THR A  49
 None
GOL  A 409 (-4.0A)
CL  A 403 ( 4.0A)
None
None
 1.49A 5x1bG-4h19A:
undetectable
5x1bN-4h19A:
undetectable
5x1bO-4h19A:
undetectable		 5x1bG-4h19A:
13.11
5x1bN-4h19A:
21.11
5x1bO-4h19A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 11 ARG A  99
ARG A  90
GLY A 101
THR A 280
THR A  49
 None
GOL  A 409 (-4.0A)
CL  A 403 ( 4.0A)
None
None
 1.48A 5x1fG-4h19A:
undetectable
5x1fN-4h19A:
undetectable
5x1fO-4h19A:
undetectable		 5x1fG-4h19A:
13.11
5x1fN-4h19A:
21.11
5x1fO-4h19A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		3 / 3 LYS A  87
LEU A  84
ARG A  83
 None
 0.78A 5yw0A-4h19A:
undetectable		 5yw0A-4h19A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_G_CHDG101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 10 ARG A  99
ARG A  90
GLY A 101
THR A 280
THR A  49
 None
GOL  A 409 (-4.0A)
CL  A 403 ( 4.0A)
None
None
 1.48A 5z84G-4h19A:
undetectable
5z84N-4h19A:
0.1
5z84O-4h19A:
undetectable		 5z84G-4h19A:
13.11
5z84N-4h19A:
21.11
5z84O-4h19A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 10 ARG A  99
ARG A  90
GLY A 101
THR A 280
THR A  49
 None
GOL  A 409 (-4.0A)
CL  A 403 ( 4.0A)
None
None
 1.49A 5z85G-4h19A:
undetectable
5z85N-4h19A:
0.0
5z85O-4h19A:
undetectable		 5z85G-4h19A:
13.11
5z85N-4h19A:
21.11
5z85O-4h19A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 10 ARG A  99
ARG A  90
GLY A 101
THR A 280
THR A  49
 None
GOL  A 409 (-4.0A)
CL  A 403 ( 4.0A)
None
None
 1.49A 5z86G-4h19A:
undetectable
5z86N-4h19A:
0.2
5z86O-4h19A:
undetectable		 5z86G-4h19A:
13.11
5z86N-4h19A:
21.11
5z86O-4h19A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		5 / 10 ARG A  99
ARG A  90
GLY A 101
THR A 280
THR A  49
 None
GOL  A 409 (-4.0A)
CL  A 403 ( 4.0A)
None
None
 1.50A 5zcqG-4h19A:
undetectable
5zcqN-4h19A:
0.0
5zcqO-4h19A:
undetectable		 5zcqG-4h19A:
13.11
5zcqN-4h19A:
21.11
5zcqO-4h19A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		4 / 7 ALA A 355
TYR A 129
VAL A 112
TRP A 115
 None
 0.81A 6cduA-4h19A:
undetectable
6cduE-4h19A:
undetectable		 6cduA-4h19A:
20.26
6cduE-4h19A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		4 / 7 VAL A 112
TRP A 115
ALA A 355
TYR A 129
 None
 0.76A 6cduH-4h19A:
undetectable
6cduI-4h19A:
undetectable		 6cduH-4h19A:
20.26
6cduI-4h19A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		4 / 7 ILE A 340
GLN A 311
HIS A 315
VAL A 314
 None
 1.14A 6j20A-4h19A:
undetectable		 6j20A-4h19A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 4h19 MANDELATE RACEMASE
(Agrobacterium
fabrum) 		4 / 4 HIS A 313
LEU A 105
TYR A 258
GLY A 283
 None
 1.49A 6n91A-4h19A:
7.8		 6n91A-4h19A:
14.48