SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h1l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4h1l ANI2.3 TCR B CHAIN
(Escherichia
coli) 		3 / 3 TYR H  46
GLY H  56
ASP H  57
 None
 0.51A 3ou6C-4h1lH:
undetectable		 3ou6C-4h1lH:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 4h1l ANI2.3 TCR B CHAIN
(Escherichia
coli) 		4 / 7 ALA H  85
VAL H  76
TYR H  87
ARG H  34
 None
 1.00A 4ijiH-4h1lH:
undetectable		 4ijiH-4h1lH:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 4h1l ANI2.3 TCR A CHAIN
(Escherichia
coli) 		4 / 6 LEU G  43
PHE G  89
ILE G 102
PHE G 103
 None
 1.13A 4y4dA-4h1lG:
undetectable		 4y4dA-4h1lG:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 4h1l ANI2.3 TCR A CHAIN
ANI2.3 TCR B CHAIN
(Escherichia
coli) 		5 / 12 ALA H  90
TYR H  31
TYR G  31
PHE G  33
GLY G  27
 None
 1.20A 5fsaA-4h1lH:
undetectable		 5fsaA-4h1lH:
14.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 4h1l ANI2.3 TCR B CHAIN
(Escherichia
coli) 		5 / 8 TYR H  45
LYS H  55
SER H  63
THR H  75
THR H  77
 None
 0.58A 5jhdE-4h1lH:
20.5
5jhdG-4h1lH:
5.7		 5jhdE-4h1lH:
91.07
5jhdG-4h1lH:
22.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 4h1l ANI2.3 TCR B CHAIN
(Escherichia
coli) 		4 / 5 TYR H  45
LYS H  55
GLY H  61
SER H  63
 None
 0.54A 5jhdJ-4h1lH:
20.7		 5jhdJ-4h1lH:
91.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)		 4h1l ANI2.3 TCR A CHAIN
ANI2.3 TCR B CHAIN
(Escherichia
coli;
Escherichia
coli) 		4 / 7 GLN G   5
GLY H  40
ILE G 102
ASP H  57
 None
 1.01A 5vlmC-4h1lG:
undetectable		 5vlmC-4h1lG:
23.08