SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h1s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 GLY A 175
ALA A 112
HIS A 220
ILE A 173
GLY A 116
 None
None
ZN  A 602 (-3.3A)
None
None
 1.19A 1c9sN-4h1sA:
undetectable
1c9sO-4h1sA:
undetectable		 1c9sN-4h1sA:
9.39
1c9sO-4h1sA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 9 GLY A 175
ALA A 112
HIS A 220
ILE A 173
GLY A 116
 None
None
ZN  A 602 (-3.3A)
None
None
 1.15A 1c9sQ-4h1sA:
undetectable
1c9sR-4h1sA:
undetectable		 1c9sQ-4h1sA:
9.39
1c9sR-4h1sA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 12 HIS A 118
ASP A  85
LEU A 184
GLY A 392
PHE A 283
 PO4  A 604 (-3.8A)
ZN  A 602 (-2.8A)
None
None
None
 1.24A 1d4fC-4h1sA:
undetectable		 1d4fC-4h1sA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 ASP A 226
GLY A 241
VAL A 239
ILE A 229
GLY A 219
 None
 1.35A 1fohA-4h1sA:
1.8		 1fohA-4h1sA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 ASP A 226
GLY A 241
VAL A 239
ILE A 229
GLY A 219
 None
 1.36A 1fohB-4h1sA:
undetectable		 1fohB-4h1sA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 12 LEU A 132
LEU A 127
VAL A 124
LEU A 150
ALA A 146
 None
 0.95A 1gseB-4h1sA:
undetectable		 1gseB-4h1sA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 GLY A 116
GLY A 175
ALA A 112
HIS A 220
ILE A 173
 None
None
None
ZN  A 602 (-3.3A)
None
 1.12A 1gtfJ-4h1sA:
undetectable
1gtfK-4h1sA:
undetectable		 1gtfJ-4h1sA:
9.39
1gtfK-4h1sA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 11 LEU A 363
GLU A 543
ILE A 369
VAL A 527
PHE A 421
 None
 1.40A 1gx9A-4h1sA:
undetectable		 1gx9A-4h1sA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 11 ARG A 354
GLY A 391
GLY A 447
PHE A 500
ASP A 506
 PO4  A 604 (-2.8A)
None
None
None
None
 1.23A 1ho5A-4h1sA:
36.7		 1ho5A-4h1sA:
29.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		7 / 11 ARG A 354
GLY A 392
ARG A 395
PHE A 417
GLY A 447
PHE A 500
ASP A 506
 PO4  A 604 (-2.8A)
None
PO4  A 604 (-2.9A)
None
None
None
None
 0.61A 1ho5A-4h1sA:
36.7		 1ho5A-4h1sA:
29.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_B_ADNB2604_1
(5'-NUCLEOTIDASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 ARG A 354
GLY A 391
GLY A 447
PHE A 500
ASP A 506
 PO4  A 604 (-2.8A)
None
None
None
None
 1.26A 1ho5B-4h1sA:
22.9		 1ho5B-4h1sA:
29.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_B_ADNB2604_1
(5'-NUCLEOTIDASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		7 / 10 ARG A 354
GLY A 392
ARG A 395
PHE A 417
GLY A 447
PHE A 500
ASP A 506
 PO4  A 604 (-2.8A)
None
PO4  A 604 (-2.9A)
None
None
None
None
 0.61A 1ho5B-4h1sA:
22.9		 1ho5B-4h1sA:
29.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_B_ADNB2604_1
(5'-NUCLEOTIDASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 ARG A 354
GLY A 392
PHE A 500
GLY A 447
PHE A 508
 PO4  A 604 (-2.8A)
None
None
None
None
 1.47A 1ho5B-4h1sA:
22.9		 1ho5B-4h1sA:
29.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 5 GLY A 123
SER A 185
THR A 181
PHE A 120
 None
 1.32A 1icuC-4h1sA:
undetectable
1icuD-4h1sA:
undetectable		 1icuC-4h1sA:
18.66
1icuD-4h1sA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 5 GLY A 123
SER A 185
THR A 181
PHE A 120
 None
 1.38A 1icvA-4h1sA:
undetectable
1icvB-4h1sA:
undetectable		 1icvA-4h1sA:
18.66
1icvB-4h1sA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 ASP A 226
GLY A 241
VAL A 239
ILE A 229
GLY A 219
 None
 1.32A 1pn0A-4h1sA:
1.5		 1pn0A-4h1sA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 ASP A 226
GLY A 241
VAL A 239
ILE A 229
GLY A 219
 None
 1.34A 1pn0B-4h1sA:
1.8		 1pn0B-4h1sA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 GLY A 175
ALA A 112
HIS A 220
ILE A 173
GLY A 116
 None
None
ZN  A 602 (-3.3A)
None
None
 1.13A 1utdE-4h1sA:
undetectable
1utdF-4h1sA:
undetectable		 1utdE-4h1sA:
9.39
1utdF-4h1sA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 GLY A 175
ALA A 112
HIS A 220
ILE A 173
GLY A 116
 None
None
ZN  A 602 (-3.3A)
None
None
 1.15A 1utdH-4h1sA:
undetectable
1utdI-4h1sA:
undetectable		 1utdH-4h1sA:
9.39
1utdI-4h1sA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 7 LEU A 501
PHE A 421
LEU A 450
MET A 368
 None
 1.01A 1wrlE-4h1sA:
undetectable
1wrlF-4h1sA:
undetectable		 1wrlE-4h1sA:
9.79
1wrlF-4h1sA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 7 TYR A 110
THR A  34
VAL A  61
GLY A  60
 None
 0.97A 2a1mA-4h1sA:
undetectable		 2a1mA-4h1sA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 9 LEU A 164
VAL A 171
GLY A 172
VAL A 240
ILE A  31
 None
 1.18A 2a1oB-4h1sA:
undetectable		 2a1oB-4h1sA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 8 HIS A 220
GLY A 222
ASN A 245
SER A 244
 ZN  A 602 (-3.3A)
None
ZN  A 603 ( 4.6A)
None
 1.03A 2a8tB-4h1sA:
undetectable		 2a8tB-4h1sA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_SAMA201_0
(UPF0066 PROTEIN
AF_0241)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		6 / 12 GLN A 279
TYR A 176
LYS A 179
GLY A 219
LEU A 218
ASP A 226
 None
 1.34A 2nv4A-4h1sA:
undetectable		 2nv4A-4h1sA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 5 PRO A 416
ALA A 413
ASP A 524
ASP A 522
 None
 1.07A 2nyuB-4h1sA:
undetectable		 2nyuB-4h1sA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		3 / 3 SER A 549
HIS A 456
ASP A 485
 None
 0.85A 2oxtA-4h1sA:
undetectable		 2oxtA-4h1sA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_B_LNRB200_1
(D7R4 PROTEIN)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 GLU A  42
ILE A 324
ARG A 328
GLU A 409
ASP A 332
 None
 1.46A 2qeoB-4h1sA:
undetectable		 2qeoB-4h1sA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 8 ARG A  40
SER A 396
ASP A  47
ALA A 413
 None
 1.27A 2rk8A-4h1sA:
undetectable		 2rk8A-4h1sA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		3 / 3 LEU A 115
MET A 113
MET A 225
 None
 0.96A 2vavF-4h1sA:
undetectable		 2vavF-4h1sA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 8 LEU A 132
LEU A 127
LEU A 150
ALA A 146
 None
 0.75A 2vcvP-4h1sA:
undetectable		 2vcvP-4h1sA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		3 / 3 ASP A  85
HIS A 118
HIS A  38
 ZN  A 602 (-2.8A)
PO4  A 604 (-3.8A)
ZN  A 603 ( 3.4A)
 0.71A 2xxgA-4h1sA:
undetectable		 2xxgA-4h1sA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		3 / 3 ASP A  85
HIS A 118
HIS A  38
 ZN  A 602 (-2.8A)
PO4  A 604 (-3.8A)
ZN  A 603 ( 3.4A)
 0.71A 2xxgC-4h1sA:
undetectable		 2xxgC-4h1sA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 9 ALA A  83
SER A 221
LEU A 200
VAL A 204
ILE A 229
 None
 1.02A 3claA-4h1sA:
undetectable		 3claA-4h1sA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 12 ASP A 226
GLY A 241
LEU A 218
SER A 178
ALA A 114
 None
 1.29A 3d91A-4h1sA:
undetectable		 3d91A-4h1sA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 7 TYR A 176
GLY A 241
VAL A 267
LEU A 200
 None
 0.92A 3elzA-4h1sA:
undetectable		 3elzA-4h1sA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 7 TYR A 176
GLY A 241
VAL A 275
LEU A 200
 None
 0.93A 3elzA-4h1sA:
undetectable		 3elzA-4h1sA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 12 LEU A  80
VAL A 240
GLY A 241
LEU A 287
ILE A 308
 None
 1.08A 3ijdB-4h1sA:
undetectable		 3ijdB-4h1sA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		6 / 10 LEU A 218
ASP A 237
VAL A 238
ILE A 292
VAL A  78
ILE A 216
 None
 1.41A 3oxwB-4h1sA:
undetectable		 3oxwB-4h1sA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 9 GLY A  89
ASP A 121
GLY A 393
ILE A 394
ILE A 525
 None
 0.93A 3s53A-4h1sA:
undetectable		 3s53A-4h1sA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		3 / 3 ARG A 395
ARG A  40
ASP A  36
 PO4  A 604 (-2.9A)
None
ZN  A 603 (-3.1A)
 0.80A 3wipG-4h1sA:
undetectable
3wipH-4h1sA:
undetectable		 3wipG-4h1sA:
18.62
3wipH-4h1sA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 11 ALA A 135
GLY A  84
ILE A 173
VAL A 101
LEU A 131
 None
 0.96A 3zosA-4h1sA:
undetectable
3zosB-4h1sA:
undetectable		 3zosA-4h1sA:
22.90
3zosB-4h1sA:
22.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 9 ASN A 390
GLY A 391
GLY A 393
GLY A 447
ASP A 506
 None
 1.30A 3ztvA-4h1sA:
40.8		 3ztvA-4h1sA:
31.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		6 / 9 ASN A 390
GLY A 392
GLY A 393
PHE A 417
GLY A 447
ASP A 506
 None
 0.44A 3ztvA-4h1sA:
40.8		 3ztvA-4h1sA:
31.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 5 LEU A 184
HIS A 437
GLU A 448
HIS A 440
 None
 1.13A 4a7bB-4h1sA:
undetectable		 4a7bB-4h1sA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 12 ILE A 343
GLY A 404
ILE A 532
MET A 360
LEU A 346
 None
 1.10A 4a81A-4h1sA:
undetectable		 4a81A-4h1sA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFU_A_KANA401_1
(APH(2')-ID)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 12 ASP A  85
HIS A 118
ASP A  36
GLU A 180
GLU A 196
 ZN  A 602 (-2.8A)
PO4  A 604 (-3.8A)
ZN  A 603 (-3.1A)
None
None
 1.35A 4dfuA-4h1sA:
undetectable		 4dfuA-4h1sA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFU_B_KANB402_1
(APH(2')-ID)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 12 ASP A  85
HIS A 118
ASP A  36
GLU A 180
GLU A 196
 ZN  A 602 (-2.8A)
PO4  A 604 (-3.8A)
ZN  A 603 (-3.1A)
None
None
 1.34A 4dfuB-4h1sA:
undetectable		 4dfuB-4h1sA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 7 ASP A  47
ASN A 410
GLU A 409
ASP A 399
 None
 1.19A 4fevB-4h1sA:
undetectable		 4fevB-4h1sA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 7 ASP A  47
ASN A 410
GLU A 409
ASP A 399
 None
 1.17A 4fewB-4h1sA:
undetectable		 4fewB-4h1sA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 9 VAL A 240
VAL A 239
VAL A 171
ILE A 173
ALA A 114
 None
 1.18A 4fwdA-4h1sA:
undetectable		 4fwdA-4h1sA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 9 VAL A 240
VAL A 239
VAL A 171
ILE A 173
GLY A 175
 None
 1.00A 4fwdA-4h1sA:
undetectable		 4fwdA-4h1sA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 8 ASP A  47
ASN A 410
GLU A 409
ASP A 399
 None
 1.18A 4gkhD-4h1sA:
undetectable		 4gkhD-4h1sA:
20.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		7 / 9 ARG A 354
ASN A 390
GLY A 391
GLY A 393
GLY A 447
PHE A 500
ASP A 506
 PO4  A 604 (-2.8A)
None
None
None
None
None
None
 1.09A 4h2fA-4h1sA:
38.8		 4h2fA-4h1sA:
94.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		9 / 9 ARG A 354
ASN A 390
GLY A 392
GLY A 393
ARG A 395
PHE A 417
GLY A 447
PHE A 500
ASP A 506
 PO4  A 604 (-2.8A)
None
None
None
PO4  A 604 (-2.9A)
None
None
None
None
 0.35A 4h2fA-4h1sA:
38.8		 4h2fA-4h1sA:
94.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 9 ASN A 390
GLY A 393
ARG A 395
PHE A 500
ASP A 506
 None
None
PO4  A 604 (-2.9A)
None
None
 1.29A 4h2fA-4h1sA:
38.8		 4h2fA-4h1sA:
94.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4H2G_A_ADNA603_1
(5'-NUCLEOTIDASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		7 / 9 ARG A 354
ASN A 390
GLY A 391
GLY A 393
GLY A 447
PHE A 500
ASP A 506
 PO4  A 604 (-2.8A)
None
None
None
None
None
None
 1.14A 4h2gA-4h1sA:
56.0		 4h2gA-4h1sA:
94.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4H2G_A_ADNA603_1
(5'-NUCLEOTIDASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		9 / 9 ARG A 354
ASN A 390
GLY A 392
GLY A 393
ARG A 395
PHE A 417
GLY A 447
PHE A 500
ASP A 506
 PO4  A 604 (-2.8A)
None
None
None
PO4  A 604 (-2.9A)
None
None
None
None
 0.22A 4h2gA-4h1sA:
56.0		 4h2gA-4h1sA:
94.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 12 GLY A 284
GLY A  59
LEU A 287
LEU A 310
TYR A 110
 None
 1.07A 4lg1A-4h1sA:
undetectable		 4lg1A-4h1sA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 12 GLY A 284
GLY A  59
LEU A 287
LEU A 310
TYR A 110
 None
 1.09A 4lg1B-4h1sA:
undetectable		 4lg1B-4h1sA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 12 GLY A 284
GLY A  59
LEU A 287
LEU A 310
TYR A 110
 None
 1.08A 4lg1C-4h1sA:
undetectable		 4lg1C-4h1sA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 12 GLY A 393
GLY A 392
ASN A 390
GLY A 505
ASP A 506
 None
 0.82A 4n09B-4h1sA:
undetectable		 4n09B-4h1sA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 12 GLY A 393
GLY A 392
ASN A 390
GLY A 505
ASP A 506
 None
 0.83A 4n09C-4h1sA:
undetectable		 4n09C-4h1sA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 12 GLY A 393
GLY A 392
ASN A 390
GLY A 505
ASP A 506
 None
 0.83A 4n09D-4h1sA:
undetectable		 4n09D-4h1sA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OMW_D_TE4D202_1
(BETA-LACTOGLOBULIN)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 9 LEU A 191
PRO A 187
ASN A 143
ALA A 199
GLU A 194
 None
 1.39A 4omwD-4h1sA:
undetectable		 4omwD-4h1sA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 12 ASP A 524
SER A 520
ASN A 499
GLY A 418
GLY A 521
 None
 1.31A 4pevB-4h1sA:
undetectable		 4pevB-4h1sA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA207_0
(OXIDOREDUCTASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 4 GLU A 180
GLY A 507
HIS A 440
ARG A 441
 None
 1.24A 4r82A-4h1sA:
undetectable
4r82B-4h1sA:
undetectable		 4r82A-4h1sA:
16.05
4r82B-4h1sA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 7 ASN A 186
PRO A 187
PHE A 120
PHE A  93
 None
 1.34A 4v32A-4h1sA:
undetectable		 4v32A-4h1sA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 5 ASP A 121
ASP A 524
PHE A 500
GLY A 419
 None
 1.21A 4xp6A-4h1sA:
undetectable		 4xp6A-4h1sA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 11 VAL A 277
VAL A 267
VAL A 275
TYR A 176
ILE A 197
 None
 0.99A 5e4dB-4h1sA:
undetectable		 5e4dB-4h1sA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 6 VAL A 469
TYR A 459
VAL A 452
HIS A 456
 None
 0.90A 5eckA-4h1sA:
undetectable		 5eckA-4h1sA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 6 VAL A 469
TYR A 459
VAL A 452
HIS A 456
 None
 0.88A 5eckD-4h1sA:
undetectable		 5eckD-4h1sA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 GLY A 116
GLY A 175
ALA A 112
HIS A 220
ILE A 173
 None
None
None
ZN  A 602 (-3.3A)
None
 1.14A 5eevA-4h1sA:
undetectable
5eevB-4h1sA:
undetectable		 5eevA-4h1sA:
9.39
5eevB-4h1sA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 GLY A 116
GLY A 175
ALA A 112
HIS A 220
ILE A 173
 None
None
None
ZN  A 602 (-3.3A)
None
 1.13A 5eewA-4h1sA:
undetectable
5eewB-4h1sA:
undetectable		 5eewA-4h1sA:
9.39
5eewB-4h1sA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 GLY A 116
GLY A 175
ALA A 112
HIS A 220
ILE A 173
 None
None
None
ZN  A 602 (-3.3A)
None
 1.14A 5eexA-4h1sA:
undetectable
5eexB-4h1sA:
undetectable		 5eexA-4h1sA:
9.39
5eexB-4h1sA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 GLY A 116
GLY A 175
ALA A 112
HIS A 220
ILE A 173
 None
None
None
ZN  A 602 (-3.3A)
None
 1.13A 5eeyA-4h1sA:
undetectable
5eeyB-4h1sA:
undetectable		 5eeyA-4h1sA:
9.39
5eeyB-4h1sA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 GLY A 116
GLY A 175
ALA A 112
HIS A 220
ILE A 173
 None
None
None
ZN  A 602 (-3.3A)
None
 1.14A 5eezA-4h1sA:
undetectable
5eezB-4h1sA:
undetectable		 5eezA-4h1sA:
9.39
5eezB-4h1sA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 GLY A 116
GLY A 175
ALA A 112
HIS A 220
ILE A 173
 None
None
None
ZN  A 602 (-3.3A)
None
 1.14A 5ef0A-4h1sA:
undetectable
5ef0B-4h1sA:
undetectable		 5ef0A-4h1sA:
9.39
5ef0B-4h1sA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 GLY A 116
GLY A 175
ALA A 112
HIS A 220
ILE A 173
 None
None
None
ZN  A 602 (-3.3A)
None
 1.14A 5ef1A-4h1sA:
undetectable
5ef1B-4h1sA:
undetectable		 5ef1A-4h1sA:
9.39
5ef1B-4h1sA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 GLY A 116
GLY A 175
ALA A 112
HIS A 220
ILE A 173
 None
None
None
ZN  A 602 (-3.3A)
None
 1.14A 5ef2A-4h1sA:
undetectable
5ef2B-4h1sA:
undetectable		 5ef2A-4h1sA:
9.39
5ef2B-4h1sA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 10 GLY A 116
GLY A 175
ALA A 112
HIS A 220
ILE A 173
 None
None
None
ZN  A 602 (-3.3A)
None
 1.14A 5ef3A-4h1sA:
undetectable
5ef3B-4h1sA:
undetectable		 5ef3A-4h1sA:
9.39
5ef3B-4h1sA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 12 HIS A 220
LEU A 115
SER A 185
ARG A 395
GLY A  89
 ZN  A 602 (-3.3A)
None
None
PO4  A 604 (-2.9A)
None
 1.02A 5m5cB-4h1sA:
undetectable		 5m5cB-4h1sA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 4 ASP A  85
HIS A 220
HIS A 243
HIS A 118
 ZN  A 602 (-2.8A)
ZN  A 602 (-3.3A)
ZN  A 602 ( 3.2A)
PO4  A 604 (-3.8A)
 1.47A 5ncdD-4h1sA:
undetectable		 5ncdD-4h1sA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 9 LEU A 127
PHE A 120
ASP A 121
HIS A 220
ILE A 139
 None
None
None
ZN  A 602 (-3.3A)
None
 1.21A 5om2A-4h1sA:
undetectable
5om2B-4h1sA:
undetectable		 5om2A-4h1sA:
9.25
5om2B-4h1sA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 6 LEU A 127
PHE A 120
ASP A 121
HIS A 220
 None
None
None
ZN  A 602 (-3.3A)
 1.14A 5om3A-4h1sA:
undetectable
5om3B-4h1sA:
undetectable		 5om3A-4h1sA:
9.25
5om3B-4h1sA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		5 / 12 ASN A 362
LEU A 415
GLY A 348
SER A 352
PHE A 449
 None
 1.15A 5vooD-4h1sA:
3.6		 5vooD-4h1sA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4h1s 5'-NUCLEOTIDASE
(Homo
sapiens) 		4 / 5 ASP A 226
ILE A  31
ASN A 117
TYR A 176
 None
None
ZN  A 602 ( 2.7A)
None
 1.19A 6a93B-4h1sA:
undetectable		 6a93B-4h1sA:
21.15