SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h32'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 4h32 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 ASN A 190
HIS A 180
GLY A 193
TYR A 192
 None
 1.09A 1c8lA-4h32A:
undetectable		 1c8lA-4h32A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 4h32 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 ASN A 190
HIS A 180
GLY A 193
TYR A 192
 None
 1.07A 1gfzA-4h32A:
undetectable		 1gfzA-4h32A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 4h32 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 LEU A 174
LEU A  66
GLY A  63
MET A 109
 None
 0.93A 1n13G-4h32A:
undetectable
1n13J-4h32A:
undetectable		 1n13G-4h32A:
11.81
1n13J-4h32A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 4h32 HEMAGGLUTININ
(Influenza
A
virus) 		5 / 11 LEU A  61
LEU A  65
SER A 233
LEU A 174
LEU A 105
 None
 1.10A 2ceoA-4h32A:
undetectable		 2ceoA-4h32A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 4h32 HEMAGGLUTININ
(Influenza
A
virus) 		5 / 12 LEU A 175
LEU A 176
LEU A  66
LEU A  61
MET A 109
 None
 1.30A 3d90B-4h32A:
undetectable		 3d90B-4h32A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_1
(PROTEASE)		 4h32 HEMAGGLUTININ
(Influenza
A
virus) 		5 / 12 GLY A  32
ALA A  33
ILE A  36
THR A  22
VAL A  20
 None
 0.80A 3el4A-4h32A:
undetectable		 3el4A-4h32A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 4h32 HEMAGGLUTININ
HEMAGGLUTININ
(Influenza
A
virus;
Influenza
A
virus) 		3 / 3 GLN A 298
ASP B 410
GLN B 406
 None
 0.84A 4aztA-4h32A:
undetectable		 4aztA-4h32A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_A_FLPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4h32 HEMAGGLUTININ
(Influenza
A
virus) 		5 / 10 TYR A 257
VAL A 112
ILE A  83
LEU A 176
LEU A  65
 None
 1.48A 4jtqA-4h32A:
undetectable		 4jtqA-4h32A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_A_FLPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4h32 HEMAGGLUTININ
(Influenza
A
virus) 		5 / 10 VAL A 112
TRP A  80
ILE A  83
LEU A 176
LEU A  65
 None
 1.22A 4jtqA-4h32A:
undetectable		 4jtqA-4h32A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4h32 HEMAGGLUTININ
(Influenza
A
virus) 		5 / 12 PHE A 115
LEU A  75
LEU A 175
TYR A 253
LEU A 173
 None
 1.02A 5ljeA-4h32A:
undetectable		 5ljeA-4h32A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 4h32 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 4 GLU A  38
THR A  39
THR B 424
LEU A 315
 None
 1.36A 5v96B-4h32A:
undetectable		 5v96B-4h32A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 4h32 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 8 PRO A 168
THR A 169
TRP A 177
PRO A 251
 None
 1.34A 5x2sI-4h32A:
undetectable
5x2sJ-4h32A:
undetectable
5x2sK-4h32A:
undetectable		 5x2sI-4h32A:
17.03
5x2sJ-4h32A:
19.60
5x2sK-4h32A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 4h32 HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 GLN A 188
TYR A 192
ASN A 194
 None
 0.69A 6dwdC-4h32A:
undetectable		 6dwdC-4h32A:
20.72