SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h44'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4h44 APOCYTOCHROME F
(Nostoc
sp.
PCC
7120) 		3 / 3 GLN C 159
HIS C  26
ARG C 155
 None
HEM  C 301 (-3.5A)
None
 0.79A 1zlqA-4h44C:
undetectable		 1zlqA-4h44C:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 4h44 APOCYTOCHROME F
(Nostoc
sp.
PCC
7120) 		5 / 12 ILE C  52
ILE C 127
VAL C 101
VAL C 114
ILE C  20
 None
 0.94A 2nnhA-4h44C:
undetectable		 2nnhA-4h44C:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4h44 APOCYTOCHROME F
(Nostoc
sp.
PCC
7120) 		3 / 3 THR C 201
ASP C 229
SER C 173
 None
 0.73A 2nxeA-4h44C:
undetectable		 2nxeA-4h44C:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4h44 APOCYTOCHROME F
(Nostoc
sp.
PCC
7120) 		3 / 3 THR C 201
ASP C 229
SER C 173
 None
 0.65A 2nxeB-4h44C:
undetectable		 2nxeB-4h44C:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 4h44 APOCYTOCHROME F
(Nostoc
sp.
PCC
7120) 		5 / 12 ILE C 180
SER C 173
PRO C 212
LEU C 217
ILE C 183
 None
 1.15A 3cd2A-4h44C:
undetectable		 3cd2A-4h44C:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 4h44 APOCYTOCHROME F
(Nostoc
sp.
PCC
7120) 		4 / 8 VAL C  34
VAL C  72
ASN C 154
GLY C 153
 None
HEM  C 301 (-4.3A)
HEM  C 301 (-4.1A)
HEM  C 301 ( 4.7A)
 0.91A 3hjoB-4h44C:
undetectable		 3hjoB-4h44C:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4h44 APOCYTOCHROME F
CYTOCHROME B6-F
COMPLEX SUBUNIT 6
(Nostoc
sp.
PCC
7120) 		4 / 6 ILE E  17
GLY E  20
ILE E  30
LEU C 267
 None
 0.74A 4o8fB-4h44E:
undetectable		 4o8fB-4h44E:
16.67