SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h4g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9P_B_DESB459_1 (ESTROGEN-RELATED RECEPTOR GAMMA)	4h4g	(3R)-HYDROXYMYRISTOY L-[ACYL-CARRIER-PROT EIN] DEHYDRATASE (Burkholderia thailandensis)	5 / 12	LEU A 81 LEU A 75 ALA A 74 LEU A 117 LEU A 35	None	1.27A	1s9pB-4h4gA: undetectable	1s9pB-4h4gA: 20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QHF_A_NCAA493_0 (CHORISMATE SYNTHASE)	4h4g	(3R)-HYDROXYMYRISTOY L-[ACYL-CARRIER-PROT EIN] DEHYDRATASE (Burkholderia thailandensis)	5 / 11	ALA A 76 ILE A 72 ALA A 147 ALA A 135 VAL A 121	None	1.07A	2qhfA-4h4gA: undetectable	2qhfA-4h4gA: 17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW4_A_SAMA801_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I)	4h4g	(3R)-HYDROXYMYRISTOY L-[ACYL-CARRIER-PROT EIN] DEHYDRATASE (Burkholderia thailandensis)	5 / 12	ILE A 43 THR A 83 ALA A 78 LEU A 119 VAL A 31	None	1.20A	5hw4A-4h4gA: undetectable	5hw4A-4h4gA: 22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW4_C_SAMC801_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I)	4h4g	(3R)-HYDROXYMYRISTOY L-[ACYL-CARRIER-PROT EIN] DEHYDRATASE (Burkholderia thailandensis)	5 / 12	ILE A 43 THR A 83 ALA A 78 LEU A 119 VAL A 31	None	1.17A	5hw4C-4h4gA: undetectable	5hw4C-4h4gA: 22.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1S9P_B_DESB459_1","ESTROGEN-RELATED RECEPTOR GAMMA","4h4g","(3R)-HYDROXYMYRISTOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE","Burkholderia thailandensis",5,"LEU A  81;LEU A  75;ALA A  74;LEU A 117;LEU A  35","None","1.27A","1s9pB-4h4gA:undetectable","1s9pB-4h4gA:20.69"],["2QHF_A_NCAA493_0","CHORISMATE SYNTHASE","4h4g","(3R)-HYDROXYMYRISTOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE","Burkholderia thailandensis",5,"ALA A  76;ILE A  72;ALA A 147;ALA A 135;VAL A 121","None","1.07A","2qhfA-4h4gA:undetectable","2qhfA-4h4gA:17.22"],["5HW4_A_SAMA801_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I","4h4g","(3R)-HYDROXYMYRISTOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE","Burkholderia thailandensis",5,"ILE A  43;THR A  83;ALA A  78;LEU A 119;VAL A  31","None","1.20A","5hw4A-4h4gA:undetectable","5hw4A-4h4gA:22.92"],["5HW4_C_SAMC801_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I","4h4g","(3R)-HYDROXYMYRISTOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE","Burkholderia thailandensis",5,"ILE A  43;THR A  83;ALA A  78;LEU A 119;VAL A  31","None","1.17A","5hw4C-4h4gA:undetectable","5hw4C-4h4gA:22.92"]]