SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h6a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_A_ADNA1501_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 4h6a ALLENE OXIDE CYCLASE
(Physcomitrella
patens) 		4 / 7 GLU A 169
LYS A 176
PRO A 170
ALA A 174
 None
 1.34A 2ejgA-4h6aA:
undetectable		 2ejgA-4h6aA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 4h6a ALLENE OXIDE CYCLASE
(Physcomitrella
patens) 		4 / 7 GLU A 169
LYS A 176
PRO A 170
ALA A 174
 None
 1.27A 2ejgB-4h6aA:
undetectable		 2ejgB-4h6aA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 4h6a ALLENE OXIDE CYCLASE
(Physcomitrella
patens) 		5 / 10 ILE A  67
VAL A  56
GLY A  98
ILE A 122
LEU A  65
 None
 1.32A 3ogpB-4h6aA:
undetectable		 3ogpB-4h6aA:
19.05