SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 4h79 CRISPR-ASSOCIATED
PROTEIN, CSE2 FAMILY
(Thermobifida
fusca) 		4 / 7 PHE A 192
GLU A 114
LEU A 112
LEU A 129
 None
EDO  A 301 (-4.7A)
None
None
 0.97A 1hk3A-4h79A:
undetectable		 1hk3A-4h79A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 4h79 CRISPR-ASSOCIATED
PROTEIN, CSE2 FAMILY
(Thermobifida
fusca) 		4 / 8 ASP A  64
PHE A  18
GLY A  60
TYR A  68
 None
 0.83A 1rmtC-4h79A:
undetectable		 1rmtC-4h79A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4h79 CRISPR-ASSOCIATED
PROTEIN, CSE2 FAMILY
(Thermobifida
fusca) 		5 / 12 GLN A 171
LEU A 168
LEU A 163
ALA A 187
VAL A 116
 None
 1.21A 3b0wA-4h79A:
2.8		 3b0wA-4h79A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_A_VIBA223_1
(THIAMINE
PYROPHOSPHOKINASE)		 4h79 CRISPR-ASSOCIATED
PROTEIN, CSE2 FAMILY
(Thermobifida
fusca) 		4 / 7 TYR A 165
LEU A 172
LEU A 149
THR A 154
 None
 1.00A 3lm8A-4h79A:
undetectable
3lm8C-4h79A:
undetectable		 3lm8A-4h79A:
17.75
3lm8C-4h79A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 4h79 CRISPR-ASSOCIATED
PROTEIN, CSE2 FAMILY
(Thermobifida
fusca) 		3 / 3 ASP A 170
GLY A 166
ASP A 164
 None
 0.64A 4xdtA-4h79A:
undetectable		 4xdtA-4h79A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 4h79 CRISPR-ASSOCIATED
PROTEIN, CSE2 FAMILY
(Thermobifida
fusca) 		5 / 12 LEU A 156
GLY A 113
GLY A 111
GLY A 109
TYR A 165
 None
None
None
EDO  A 301 (-4.7A)
None
 1.07A 6ce2B-4h79A:
undetectable		 6ce2B-4h79A:
18.75