SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h7l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4h7l UNCHARACTERIZED
PROTEIN
(Planctopirus
limnophila) 		5 / 12 THR A  57
HIS A  58
HIS A  60
GLU A  65
TYR A  67
 None
CU  A 201 (-3.4A)
CU  A 201 (-3.4A)
CU  A 201 (-2.4A)
None
 1.43A 1j36A-4h7lA:
undetectable		 1j36A-4h7lA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4h7l UNCHARACTERIZED
PROTEIN
(Planctopirus
limnophila) 		5 / 12 THR A  57
HIS A  58
HIS A  60
GLU A  65
TYR A  67
 None
CU  A 201 (-3.4A)
CU  A 201 (-3.4A)
CU  A 201 (-2.4A)
None
 1.43A 1j36B-4h7lA:
undetectable		 1j36B-4h7lA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 4h7l UNCHARACTERIZED
PROTEIN
(Planctopirus
limnophila) 		6 / 12 HIS A  60
GLU A 122
HIS A  58
GLU A  65
HIS A  47
THR A  49
 CU  A 201 (-3.4A)
None
CU  A 201 (-3.4A)
CU  A 201 (-2.4A)
None
None
 1.43A 2c6nB-4h7lA:
undetectable		 2c6nB-4h7lA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_A_TMQA611_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4h7l UNCHARACTERIZED
PROTEIN
(Planctopirus
limnophila) 		5 / 10 VAL A 104
ALA A 107
ILE A 109
ILE A  95
LEU A  80
 None
 1.11A 3hbbA-4h7lA:
undetectable		 3hbbA-4h7lA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 4h7l UNCHARACTERIZED
PROTEIN
(Planctopirus
limnophila) 		4 / 7 THR A  49
GLY A  30
PRO A  28
THR A  57
 None
 0.81A 3tajA-4h7lA:
undetectable		 3tajA-4h7lA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 4h7l UNCHARACTERIZED
PROTEIN
(Planctopirus
limnophila) 		4 / 5 ILE A 109
ILE A 112
TYR A  67
GLU A  65
 None
None
None
CU  A 201 (-2.4A)
 1.04A 4zzcE-4h7lA:
undetectable		 4zzcE-4h7lA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 4h7l UNCHARACTERIZED
PROTEIN
(Planctopirus
limnophila) 		4 / 6 VAL A  99
TYR A  67
ILE A  95
GLU A  65
 None
None
None
CU  A 201 (-2.4A)
 0.95A 5z3jA-4h7lA:
undetectable		 5z3jA-4h7lA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 4h7l UNCHARACTERIZED
PROTEIN
(Planctopirus
limnophila) 		3 / 3 HIS A  58
HIS A 101
HIS A  60
 CU  A 201 (-3.4A)
CU  A 201 (-3.8A)
CU  A 201 (-3.4A)
 0.34A 5zrdA-4h7lA:
undetectable		 5zrdA-4h7lA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)		 4h7l UNCHARACTERIZED
PROTEIN
(Planctopirus
limnophila) 		4 / 5 SER A  45
VAL A 113
ASN A 111
PRO A 119
 None
 1.39A 6fi4A-4h7lA:
undetectable
6fi4B-4h7lA:
undetectable		 6fi4A-4h7lA:
22.08
6fi4B-4h7lA:
3.42