SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h7m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7B_A_HLTA4001_1 (SERUM ALBUMIN)	4h7m	ENDO-1,4-BETA-GLUCAN ASE (Trichoderma harzianum)	4 / 5	ARG A 100 ALA A 101 ASP A 133 GLY A 135	None	0.92A	1e7bA-4h7mA: undetectable	1e7bA-4h7mA: 13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_C_CELC682_2 (PROSTAGLANDIN G/H SYNTHASE 2)	4h7m	ENDO-1,4-BETA-GLUCAN ASE (Trichoderma harzianum)	4 / 7	ARG A 187 SER A 82 LEU A 124 ILE A 224	None	1.07A	3ln1C-4h7mA: undetectable	3ln1C-4h7mA: 16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZQE_B_DXCB1079_0 (PROTEIN PRGI, CELL INVASION PROTEIN SIPD)	4h7m	ENDO-1,4-BETA-GLUCAN ASE (Trichoderma harzianum)	5 / 11	LYS A 180 GLN A 162 LEU A 124 TYR A 155 ARG A 187	None	1.47A	3zqeA-4h7mA: undetectable 3zqeB-4h7mA: undetectable	3zqeA-4h7mA: 20.26 3zqeB-4h7mA: 20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FOG_A_C2FA302_0 (THYMIDYLATE SYNTHASE)	4h7m	ENDO-1,4-BETA-GLUCAN ASE (Trichoderma harzianum)	5 / 11	ILE A 146 TRP A 151 TRP A 175 LEU A 128 TYR A 202	None	1.23A	4fogA-4h7mA: undetectable	4fogA-4h7mA: 19.78

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E7B_A_HLTA4001_1","SERUM ALBUMIN","4h7m","ENDO-1,4-BETA-GLUCANASE","Trichoderma harzianum",4,"ARG A 100;ALA A 101;ASP A 133;GLY A 135","None","0.92A","1e7bA-4h7mA:undetectable","1e7bA-4h7mA:13.85"],["3LN1_C_CELC682_2","PROSTAGLANDIN G\/H SYNTHASE 2","4h7m","ENDO-1,4-BETA-GLUCANASE","Trichoderma harzianum",4,"ARG A 187;SER A  82;LEU A 124;ILE A 224","None","1.07A","3ln1C-4h7mA:undetectable","3ln1C-4h7mA:16.44"],["3ZQE_B_DXCB1079_0","PROTEIN PRGI, CELL INVASION PROTEIN SIPD","4h7m","ENDO-1,4-BETA-GLUCANASE","Trichoderma harzianum",5,"LYS A 180;GLN A 162;LEU A 124;TYR A 155;ARG A 187","None","1.47A","3zqeA-4h7mA:undetectable;3zqeB-4h7mA:undetectable","3zqeA-4h7mA:20.26;3zqeB-4h7mA:20.26"],["4FOG_A_C2FA302_0","THYMIDYLATE SYNTHASE","4h7m","ENDO-1,4-BETA-GLUCANASE","Trichoderma harzianum",5,"ILE A 146;TRP A 151;TRP A 175;LEU A 128;TYR A 202","None","1.23A","4fogA-4h7mA:undetectable","4fogA-4h7mA:19.78"]]