SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h7u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 6 LEU A 228
ILE A 279
ARG A 542
VAL A  42
 None
 0.96A 1db1A-4h7uA:
undetectable		 1db1A-4h7uA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 7 ILE A 133
TYR A 567
PHE A 564
PHE A 533
 None
 1.00A 1e71M-4h7uA:
undetectable		 1e71M-4h7uA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 7 ILE A 133
TYR A 567
PHE A 564
PHE A 533
 None
 1.03A 1e72M-4h7uA:
undetectable		 1e72M-4h7uA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 10 ILE A 389
ALA A 325
SER A 432
ILE A 431
ILE A 462
 None
 1.20A 1j3jA-4h7uA:
undetectable		 1j3jA-4h7uA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 ASN A 117
SER A 118
ASP A 114
PRO A 560
ALA A 563
 None
 1.45A 1s14B-4h7uA:
undetectable		 1s14B-4h7uA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 LEU A  43
VAL A 243
ILE A 290
SER A 294
LEU A 541
 None
FED  A 801 (-3.8A)
FED  A 801 (-4.9A)
None
None
 1.16A 1s19A-4h7uA:
undetectable		 1s19A-4h7uA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 9 LEU A 499
VAL A 425
ALA A 424
MET A 329
PHE A 486
 None
 1.19A 1tbfA-4h7uA:
undetectable		 1tbfA-4h7uA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 11 GLY A 282
ALA A  21
LEU A 242
VAL A 246
VAL A 259
 FED  A 801 (-3.5A)
None
FED  A 801 (-4.1A)
None
None
 0.97A 1ukbA-4h7uA:
undetectable		 1ukbA-4h7uA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 5 PHE A 178
PHE A 479
MET A 473
SER A 469
 None
 1.01A 1wrlC-4h7uA:
undetectable		 1wrlC-4h7uA:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 5 ASP A 198
GLY A 162
ALA A 171
ILE A 156
 None
 0.93A 2aofA-4h7uA:
undetectable		 2aofA-4h7uA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 8 GLY A 282
GLY A  24
THR A  25
ALA A  26
 FED  A 801 (-3.5A)
FED  A 801 (-3.3A)
FED  A 801 (-3.2A)
FED  A 801 (-3.5A)
 0.54A 2ej3A-4h7uA:
undetectable		 2ej3A-4h7uA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 6 ASP A 331
TYR A 417
PHE A 474
LEU A 423
 None
 1.07A 2w98A-4h7uA:
undetectable
2w98B-4h7uA:
undetectable		 2w98A-4h7uA:
20.63
2w98B-4h7uA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 GLY A 295
THR A 309
GLU A 298
THR A 254
ILE A 296
 None
 0.92A 2wa2B-4h7uA:
2.6		 2wa2B-4h7uA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 6 LEU A 421
THR A 332
PHE A 178
LEU A 181
 None
 1.07A 2wm3A-4h7uA:
4.9		 2wm3A-4h7uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 7 TRP A 119
VAL A 514
SER A 321
THR A 557
 None
None
None
FED  A 801 (-3.7A)
 1.09A 3arrA-4h7uA:
undetectable		 3arrA-4h7uA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 GLY A  24
GLY A  22
ILE A  72
GLY A  98
GLY A  99
 FED  A 801 (-3.3A)
FED  A 801 (-3.3A)
None
None
FED  A 801 (-3.1A)
 0.98A 3axzA-4h7uA:
undetectable		 3axzA-4h7uA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 7 SER A  32
SER A 226
LYS A 166
ASP A 215
 None
 1.30A 3bc9A-4h7uA:
undetectable		 3bc9A-4h7uA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 9 THR A  25
VAL A  20
LEU A  34
ILE A 572
GLY A 283
 FED  A 801 (-3.2A)
None
None
None
FED  A 801 (-3.5A)
 1.23A 3cv9A-4h7uA:
undetectable		 3cv9A-4h7uA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 GLY A 359
GLY A  61
SER A  64
VAL A 107
HIS A 556
 None
None
None
FED  A 801 (-3.8A)
FED  A 801 (-3.6A)
 1.11A 3dlcA-4h7uA:
2.8		 3dlcA-4h7uA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 LEU A  28
GLY A 282
GLY A  23
LEU A  97
CYH A 100
 None
FED  A 801 (-3.5A)
FED  A 801 ( 4.7A)
None
FED  A 801 (-3.2A)
 1.11A 3e23A-4h7uA:
undetectable		 3e23A-4h7uA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 LEU A  28
GLY A 283
GLY A  23
LEU A  97
CYH A 100
 None
FED  A 801 (-3.5A)
FED  A 801 ( 4.7A)
None
FED  A 801 (-3.2A)
 0.99A 3e23A-4h7uA:
undetectable		 3e23A-4h7uA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 8 GLY A 283
ILE A 290
VAL A 280
VAL A 543
 FED  A 801 (-3.5A)
FED  A 801 (-4.9A)
None
None
 0.79A 3fi0G-4h7uA:
undetectable		 3fi0G-4h7uA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 8 GLY A 283
ILE A 290
VAL A 280
VAL A 543
 FED  A 801 (-3.5A)
FED  A 801 (-4.9A)
None
None
 0.78A 3fi0Q-4h7uA:
undetectable		 3fi0Q-4h7uA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 11 LEU A 291
ALA A 286
GLY A  22
VAL A 246
ILE A 290
 None
FED  A 801 (-3.1A)
FED  A 801 (-3.3A)
None
FED  A 801 (-4.9A)
 0.98A 3oxxD-4h7uA:
undetectable		 3oxxD-4h7uA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 6 ASP A  17
TYR A  16
ASP A  15
LYS A 275
 None
 1.24A 3pocB-4h7uA:
undetectable		 3pocB-4h7uA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 10 ILE A 389
ALA A 325
SER A 432
ILE A 431
ILE A 462
 None
 1.20A 3qgtA-4h7uA:
undetectable		 3qgtA-4h7uA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_B_CP6B609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 10 ILE A 389
ALA A 325
SER A 432
ILE A 431
ILE A 462
 None
 1.19A 3qgtB-4h7uA:
undetectable		 3qgtB-4h7uA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 8 LEU A  97
ALA A 224
SER A 222
SER A 101
 None
 1.05A 3rodA-4h7uA:
undetectable		 3rodA-4h7uA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 5 SER A 248
THR A 254
GLU A 273
ASP A  15
 None
 1.36A 3tm4A-4h7uA:
3.3		 3tm4A-4h7uA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 5 SER A 248
THR A 254
GLU A 273
ASP A  15
 None
 1.37A 3tm4B-4h7uA:
3.4		 3tm4B-4h7uA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 TYR A 212
THR A 185
ALA A 360
LEU A 207
PHE A 178
 None
 1.47A 3vw1B-4h7uA:
undetectable		 3vw1B-4h7uA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 SER A 223
GLY A 282
GLY A  99
GLY A  98
VAL A 544
 None
FED  A 801 (-3.5A)
FED  A 801 (-3.1A)
None
None
 1.10A 4b17A-4h7uA:
2.6		 4b17A-4h7uA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 7 GLY A  98
ALA A  47
GLU A  46
GLN A 558
 None
FED  A 801 (-3.5A)
FED  A 801 (-2.7A)
FED  A 801 (-4.3A)
 0.98A 4g0uB-4h7uA:
undetectable		 4g0uB-4h7uA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 6 GLY A  98
ALA A  47
GLU A  46
GLN A 558
 None
FED  A 801 (-3.5A)
FED  A 801 (-2.7A)
FED  A 801 (-4.3A)
 0.97A 4g0uA-4h7uA:
undetectable		 4g0uA-4h7uA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 6 ALA A 224
LEU A  28
VAL A  29
GLU A  36
 None
 0.89A 4g24A-4h7uA:
undetectable		 4g24A-4h7uA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 5 THR A 309
GLY A 297
VAL A 316
PRO A 314
 None
 1.04A 4grkA-4h7uA:
undetectable		 4grkA-4h7uA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 9 SER A 381
GLY A 383
SER A 386
ASP A 115
SER A 112
 None
 1.38A 4lb0A-4h7uA:
undetectable		 4lb0A-4h7uA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 VAL A  29
ALA A  26
TYR A 562
VAL A 561
GLY A  24
 None
FED  A 801 (-3.5A)
None
FED  A 801 (-4.6A)
FED  A 801 (-3.3A)
 1.22A 4mm4B-4h7uA:
undetectable		 4mm4B-4h7uA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 GLY A  27
ALA A 281
GLY A  23
GLY A  22
THR A 244
 None
None
FED  A 801 ( 4.7A)
FED  A 801 (-3.3A)
None
 0.96A 4o3fA-4h7uA:
undetectable		 4o3fA-4h7uA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 6 PHE A 367
LEU A 428
HIS A 556
THR A 109
 None
None
FED  A 801 (-3.6A)
None
 1.33A 4paeA-4h7uA:
undetectable		 4paeA-4h7uA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 GLY A 515
GLY A 317
ILE A 296
ASN A 313
SER A 294
 None
 1.03A 4rtmA-4h7uA:
undetectable		 4rtmA-4h7uA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 GLY A 515
GLY A 317
ILE A 296
ASN A 313
SER A 294
 None
 0.98A 4rtsA-4h7uA:
undetectable		 4rtsA-4h7uA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 7 PHE A 508
ALA A 424
ILE A 389
LEU A 463
 None
 1.05A 4uymA-4h7uA:
undetectable		 4uymA-4h7uA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 7 PHE A 508
ALA A 424
ILE A 389
LEU A 463
 None
 1.04A 4uymB-4h7uA:
undetectable		 4uymB-4h7uA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		3 / 3 VAL A  29
TYR A 562
ALA A 565
 None
 0.46A 4ybnA-4h7uA:
undetectable		 4ybnA-4h7uA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 GLY A  24
GLY A  22
ILE A  72
GLY A  98
GLY A  99
 FED  A 801 (-3.3A)
FED  A 801 (-3.3A)
None
None
FED  A 801 (-3.1A)
 1.04A 4yvgA-4h7uA:
undetectable		 4yvgA-4h7uA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 ARG A 472
PHE A 391
ALA A 501
ILE A 460
ALA A 461
 None
 1.18A 5vc0A-4h7uA:
undetectable		 5vc0A-4h7uA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 ASP A 379
ILE A 133
PHE A 564
ALA A 563
ALA A 555
 None
 1.17A 5vc0A-4h7uA:
undetectable		 5vc0A-4h7uA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W8A_A_SAMA300_0
(AUTOINDUCER SYNTHASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 12 LEU A 362
VAL A 483
PHE A 479
SER A 177
THR A 185
 None
 1.24A 5w8aA-4h7uA:
undetectable		 5w8aA-4h7uA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 4 ASP A 114
SER A 112
ASP A 115
HIS A 551
 None
 1.39A 5wyqB-4h7uA:
undetectable		 5wyqB-4h7uA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 9 ALA A 546
SER A 547
ALA A  26
VAL A 280
GLY A  24
 FED  A 801 (-3.3A)
None
FED  A 801 (-3.5A)
None
FED  A 801 (-3.3A)
 1.28A 6bklA-4h7uA:
undetectable
6bklB-4h7uA:
undetectable
6bklC-4h7uA:
undetectable
6bklD-4h7uA:
undetectable		 6bklA-4h7uA:
4.42
6bklB-4h7uA:
4.42
6bklC-4h7uA:
4.42
6bklD-4h7uA:
4.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		5 / 9 ALA A  63
SER A  64
ALA A 360
GLY A 105
ALA A 394
 None
None
None
FED  A 801 (-3.1A)
None
 1.01A 6bklE-4h7uA:
undetectable
6bklF-4h7uA:
undetectable
6bklG-4h7uA:
undetectable
6bklH-4h7uA:
undetectable		 6bklE-4h7uA:
4.42
6bklF-4h7uA:
4.42
6bklG-4h7uA:
4.42
6bklH-4h7uA:
4.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4h7u PYRANOSE
DEHYDROGENASE
(Leucoagaricus
meleagris) 		4 / 6 LEU A 428
TYR A 429
PHE A 367
GLY A 111
 None
 0.89A 6hd4B-4h7uA:
undetectable		 6hd4B-4h7uA:
8.04