SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h9k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	4h9k	HOG CHOLERA VIRUS (Pestivirus C)	3 / 3	PHE A 33 TYR A 98 PRO A 23	None	0.89A	1mcnA-4h9kA: undetectable 1mcnB-4h9kA: undetectable 1mcnP-4h9kA: undetectable	1mcnA-4h9kA: 20.85 1mcnB-4h9kA: 20.85 1mcnP-4h9kA: 7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3M8P_A_65BA562_0 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H P51 RT)	4h9k	HOG CHOLERA VIRUS (Pestivirus C)	5 / 11	LEU A 141 VAL A 165 TYR A 98 LEU A 103 TYR A 129	None	1.30A	3m8pA-4h9kA: undetectable 3m8pB-4h9kA: undetectable	3m8pA-4h9kA: 14.39 3m8pB-4h9kA: 15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_C_ZPCC1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	4h9k	HOG CHOLERA VIRUS (Pestivirus C)	5 / 12	VAL A 121 ILE A 131 GLU A 104 HIS A 99 VAL A 83	None	1.21A	4a97B-4h9kA: undetectable 4a97C-4h9kA: undetectable	4a97B-4h9kA: 18.89 4a97C-4h9kA: 18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NN4_A_SC2A1016_1 (LYSOSOMAL ALPHA-GLUCOSIDASE)	4h9k	HOG CHOLERA VIRUS (Pestivirus C)	4 / 4	HIS A 130 GLY A 119 ARG A 120 THR A 44	None None SO4 A 203 (-2.8A) None	1.33A	5nn4A-4h9kA: 0.0	5nn4A-4h9kA: 12.44

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MCN_P_DHIP1_0","IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN);PEPTIDE N-ACETYL-D-HIS-L-PRO-NH2","4h9k","HOG CHOLERA VIRUS","Pestivirus C",3,"PHE A  33;TYR A  98;PRO A  23","None","0.89A","1mcnA-4h9kA:undetectable;1mcnB-4h9kA:undetectable;1mcnP-4h9kA:undetectable","1mcnA-4h9kA:20.85;1mcnB-4h9kA:20.85;1mcnP-4h9kA:7.14"],["3M8P_A_65BA562_0","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H;P51 RT","4h9k","HOG CHOLERA VIRUS","Pestivirus C",5,"LEU A 141;VAL A 165;TYR A  98;LEU A 103;TYR A 129","None","1.30A","3m8pA-4h9kA:undetectable;3m8pB-4h9kA:undetectable","3m8pA-4h9kA:14.39;3m8pB-4h9kA:15.75"],["4A97_C_ZPCC1318_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","4h9k","HOG CHOLERA VIRUS","Pestivirus C",5,"VAL A 121;ILE A 131;GLU A 104;HIS A  99;VAL A  83","None","1.21A","4a97B-4h9kA:undetectable;4a97C-4h9kA:undetectable","4a97B-4h9kA:18.89;4a97C-4h9kA:18.89"],["5NN4_A_SC2A1016_1","LYSOSOMAL ALPHA-GLUCOSIDASE","4h9k","HOG CHOLERA VIRUS","Pestivirus C",4,"HIS A 130;GLY A 119;ARG A 120;THR A  44","None;None;SO4 A 203 (-2.8A);None","1.33A","5nn4A-4h9kA:0.0","5nn4A-4h9kA:12.44"]]