SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4h9p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1G_A_MTXA171_1
(DIHYDROFOLATE
REDUCTASE)		 4h9p DEATH
DOMAIN-ASSOCIATED
PROTEIN 6
(Homo
sapiens) 		5 / 12 ALA C 292
GLU C 272
ILE C 257
ARG C 327
LEU C 324
 None
 1.19A 1d1gA-4h9pC:
undetectable		 1d1gA-4h9pC:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 4h9p DEATH
DOMAIN-ASSOCIATED
PROTEIN 6
(Homo
sapiens) 		5 / 9 LEU C 274
ALA C 316
ASP C 315
VAL C 267
ILE C 271
 None
 1.29A 3wsjA-4h9pC:
undetectable		 3wsjA-4h9pC:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 4h9p DEATH
DOMAIN-ASSOCIATED
PROTEIN 6
(Homo
sapiens) 		4 / 6 LEU C 290
LEU C 311
THR C 262
VAL C 267
 None
 1.12A 4udaA-4h9pC:
undetectable		 4udaA-4h9pC:
21.40