SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ha7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ha7 2,5-DIAMINO-6-RIBOSY
LAMINO-4(3H)-PYRIMID
INONE 5'-PHOSPHATE
REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 185
THR A 135
THR A 107
ILE A 105
 None
 0.86A 1gtnC-4ha7A:
undetectable
1gtnD-4ha7A:
undetectable		 1gtnC-4ha7A:
15.58
1gtnD-4ha7A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 4ha7 2,5-DIAMINO-6-RIBOSY
LAMINO-4(3H)-PYRIMID
INONE 5'-PHOSPHATE
REDUCTASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 168
ILE A 149
ALA A 148
VAL A 134
LEU A  87
 None
 1.15A 2g78A-4ha7A:
undetectable		 2g78A-4ha7A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4ha7 2,5-DIAMINO-6-RIBOSY
LAMINO-4(3H)-PYRIMID
INONE 5'-PHOSPHATE
REDUCTASE
(Saccharomyces
cerevisiae) 		5 / 9 GLN A 188
VAL A 185
ILE A 103
VAL A 177
VAL A  32
 None
 1.33A 3fi0F-4ha7A:
undetectable		 3fi0F-4ha7A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC392_1
(TETX2 PROTEIN)		 4ha7 2,5-DIAMINO-6-RIBOSY
LAMINO-4(3H)-PYRIMID
INONE 5'-PHOSPHATE
REDUCTASE
(Saccharomyces
cerevisiae) 		5 / 12 GLU A 171
VAL A 177
ILE A 103
ILE A 167
GLU A 166
 None
 1.40A 4a99A-4ha7A:
undetectable
4a99C-4ha7A:
undetectable		 4a99A-4ha7A:
20.35
4a99C-4ha7A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 4ha7 2,5-DIAMINO-6-RIBOSY
LAMINO-4(3H)-PYRIMID
INONE 5'-PHOSPHATE
REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 8 SER A 227
CYH A 238
TYR A  17
GLN A  12
 None
 1.08A 4j7uD-4ha7A:
undetectable		 4j7uD-4ha7A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 4ha7 2,5-DIAMINO-6-RIBOSY
LAMINO-4(3H)-PYRIMID
INONE 5'-PHOSPHATE
REDUCTASE
(Saccharomyces
cerevisiae) 		5 / 12 SER A 227
CYH A 238
TYR A  17
MET A  62
LEU A  10
 None
 1.20A 4j7xB-4ha7A:
2.4		 4j7xB-4ha7A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4ha7 2,5-DIAMINO-6-RIBOSY
LAMINO-4(3H)-PYRIMID
INONE 5'-PHOSPHATE
REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 5 THR A  33
THR A 202
LEU A  10
LEU A  14
 None
 1.03A 4lvcB-4ha7A:
undetectable		 4lvcB-4ha7A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 4ha7 2,5-DIAMINO-6-RIBOSY
LAMINO-4(3H)-PYRIMID
INONE 5'-PHOSPHATE
REDUCTASE
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 166
ASP A 160
PRO A 151
 None
 0.74A 6berA-4ha7A:
undetectable		 6berA-4ha7A:
7.53