SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hb4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 7 LEU C 347
TYR C 365
HIS C 344
THR C 257
 None
 0.86A 1afsA-4hb4C:
undetectable		 1afsA-4hb4C:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 7 LEU C 347
TYR C 365
HIS C 344
THR C 257
 None
 0.86A 1afsB-4hb4C:
undetectable		 1afsB-4hb4C:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		5 / 6 ALA C 880
LYS C 883
ASP C 887
ALA C 888
LEU C 863
 None
None
GOL  C1102 ( 4.8A)
None
None
 1.36A 1iwhA-4hb4C:
undetectable		 1iwhA-4hb4C:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		3 / 3 PHE C 610
TRP C 570
GLU C 617
 None
 0.89A 1mogA-4hb4C:
undetectable		 1mogA-4hb4C:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q0Y_H_MOIH401_1
(FAB 9B1, HEAVY CHAIN
FAB 9B1, LIGHT CHAIN)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 7 GLU C 189
ILE C 193
TRP C 130
LEU C 126
 None
 1.37A 1q0yH-4hb4C:
undetectable
1q0yL-4hb4C:
undetectable		 1q0yH-4hb4C:
11.47
1q0yL-4hb4C:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		3 / 3 ASN C 506
TRP C 510
GLN C 494
 None
 1.43A 1xoqA-4hb4C:
undetectable		 1xoqA-4hb4C:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 6 ALA C 343
TYR C 420
ILE C 423
LEU C 323
 None
 0.83A 1xvaA-4hb4C:
undetectable
1xvaB-4hb4C:
undetectable		 1xvaA-4hb4C:
14.88
1xvaB-4hb4C:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		5 / 10 LEU C 905
ALA C 892
ILE C 889
ASP C 945
PHE C 849
 None
 1.17A 2b17A-4hb4C:
undetectable		 2b17A-4hb4C:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 6 LEU C  55
LYS C  64
LEU C 114
VAL C 107
 None
None
CL  C1106 ( 4.4A)
None
 1.12A 2dqyC-4hb4C:
undetectable		 2dqyC-4hb4C:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		5 / 9 PHE C 933
GLU C 926
ASN C 925
ILE C 971
VAL C 966
 None
 1.04A 2drdA-4hb4C:
undetectable		 2drdA-4hb4C:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 5 LEU C 297
LEU C 312
MET C 291
MET C 243
 None
 0.99A 2oaxF-4hb4C:
undetectable		 2oaxF-4hb4C:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 7 LEU C 329
VAL C 276
THR C 275
ASP C 269
 None
 0.92A 2qblA-4hb4C:
undetectable		 2qblA-4hb4C:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 8 ASP C 554
SER C 509
TYR C 557
TYR C 465
 None
 1.39A 2v0gA-4hb4C:
undetectable		 2v0gA-4hb4C:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		3 / 3 VAL C 709
ASN C 673
TRP C 676
 None
 1.02A 2y00B-4hb4C:
undetectable		 2y00B-4hb4C:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		5 / 12 LEU C 508
GLU C 484
MET C 519
ILE C 515
SER C 514
 None
 1.22A 2ydoA-4hb4C:
undetectable		 2ydoA-4hb4C:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		5 / 12 LEU C  82
ARG C  87
GLY C1043
ILE C1039
VAL C1037
 None
 1.24A 2zznA-4hb4C:
undetectable		 2zznA-4hb4C:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		3 / 3 CYH C 197
PHE C 198
PHE C 194
 None
 0.80A 3cr5X-4hb4C:
0.8		 3cr5X-4hb4C:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		5 / 12 MET C 669
ASN C 673
VAL C 680
MET C 728
LEU C 769
 None
 1.32A 3h52A-4hb4C:
undetectable		 3h52A-4hb4C:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 6 GLN C 199
LEU C 201
GLU C 202
LEU C 237
 None
 0.84A 3h5gA-4hb4C:
undetectable
3h5gC-4hb4C:
undetectable		 3h5gA-4hb4C:
2.58
3h5gC-4hb4C:
2.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 6 LEU C 237
GLN C 199
LEU C 201
GLU C 202
 None
 0.97A 3h5gB-4hb4C:
undetectable
3h5gC-4hb4C:
undetectable		 3h5gB-4hb4C:
2.58
3h5gC-4hb4C:
2.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA303_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 4 GLN C 640
GLN C 592
GLY C 590
HIS C 588
 None
 1.36A 3huoA-4hb4C:
undetectable		 3huoA-4hb4C:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 7 ASN C 268
GLU C 231
PRO C 265
TYR C 226
 None
 1.02A 3ugrA-4hb4C:
undetectable		 3ugrA-4hb4C:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		5 / 12 LEU C 350
ILE C 286
ILE C 353
ASP C 308
PHE C 311
 None
 1.28A 3vw1D-4hb4C:
3.1		 3vw1D-4hb4C:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		5 / 11 LEU C 508
ILE C 505
SER C 514
LEU C 538
ILE C 488
 None
 1.16A 4dm8A-4hb4C:
undetectable		 4dm8A-4hb4C:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		5 / 9 LEU C 791
ASP C 782
VAL C 786
GLY C 722
ILE C 724
 None
 1.05A 4dqcB-4hb4C:
undetectable		 4dqcB-4hb4C:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		5 / 10 ALA C 956
LEU C 959
PHE C 940
VAL C 936
THR C1019
 None
None
None
None
EDO  C1103 ( 4.0A)
 0.96A 4j14A-4hb4C:
undetectable		 4j14A-4hb4C:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 5 LEU C 787
VAL C 819
TYR C 773
ARG C 807
 None
 1.08A 4r7iA-4hb4C:
undetectable		 4r7iA-4hb4C:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 6 ALA C 750
THR C 751
VAL C 756
VAL C 803
 None
 0.84A 5eckA-4hb4C:
undetectable		 5eckA-4hb4C:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 6 ALA C 750
THR C 751
VAL C 756
VAL C 803
 None
 0.85A 5eckD-4hb4C:
undetectable		 5eckD-4hb4C:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 6 ALA C 750
THR C 751
VAL C 756
VAL C 803
 None
 0.77A 5eclA-4hb4C:
undetectable		 5eclA-4hb4C:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 6 ALA C 750
THR C 751
VAL C 756
VAL C 803
 None
 0.90A 5eclD-4hb4C:
undetectable		 5eclD-4hb4C:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 7 ALA C 750
THR C 751
VAL C 756
VAL C 803
 None
 0.71A 5ecmD-4hb4C:
1.9		 5ecmD-4hb4C:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 7 ALA C 750
THR C 751
VAL C 756
VAL C 803
 None
 0.73A 5ecoD-4hb4C:
1.8		 5ecoD-4hb4C:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		5 / 12 LEU C 791
ALA C 794
ILE C 679
ILE C 766
LEU C 690
 None
 1.15A 5h8tA-4hb4C:
undetectable		 5h8tA-4hb4C:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		5 / 12 LEU C 791
ALA C 794
ILE C 679
ILE C 766
LEU C 690
 None
 1.16A 5hbsA-4hb4C:
undetectable		 5hbsA-4hb4C:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		5 / 12 TRP C 366
LEU C 369
ILE C 419
ALA C 343
LEU C 340
 None
 1.20A 5ienB-4hb4C:
undetectable		 5ienB-4hb4C:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		3 / 3 HIS C 895
LYS C 894
PHE C 849
 None
 1.39A 5klaA-4hb4C:
2.4		 5klaA-4hb4C:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 8 LEU C 315
PHE C 318
ALA C 343
PHE C 279
 None
 0.99A 5m0oC-4hb4C:
undetectable		 5m0oC-4hb4C:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		5 / 9 ILE C 702
ALA C 700
ILE C 699
ILE C 766
LEU C 731
 None
 1.07A 5mvmA-4hb4C:
2.7
5mvmE-4hb4C:
2.7		 5mvmA-4hb4C:
6.53
5mvmE-4hb4C:
6.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 8 PRO C 620
ILE C 651
ILE C 652
GLU C 655
 None
 0.70A 5mvmA-4hb4C:
2.8
5mvmB-4hb4C:
2.7		 5mvmA-4hb4C:
6.53
5mvmB-4hb4C:
6.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 4 SER C1016
ALA C1017
GLN C1038
THR C1031
 None
 1.42A 5n0rA-4hb4C:
undetectable		 5n0rA-4hb4C:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 4 SER C1016
ALA C1017
GLN C1038
THR C1031
 None
 1.42A 5n0sA-4hb4C:
undetectable		 5n0sA-4hb4C:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 5 SER C1016
ALA C1017
GLN C1038
THR C1031
 None
 1.41A 5n0tA-4hb4C:
undetectable		 5n0tA-4hb4C:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 4 SER C1016
ALA C1017
GLN C1038
THR C1031
 None
 1.41A 5n0wA-4hb4C:
undetectable		 5n0wA-4hb4C:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 4 SER C1016
ALA C1017
GLN C1038
THR C1031
 None
 1.42A 5n0xA-4hb4C:
undetectable		 5n0xA-4hb4C:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Q1S_A_AWYA1103_0
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 6 LYS C 567
VAL C 603
LYS C 605
ILE C 651
 CL  C1105 ( 3.9A)
None
None
None
 1.42A 5q1sA-4hb4C:
undetectable		 5q1sA-4hb4C:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 6 ARG C 327
PHE C 318
ILE C 286
THR C 282
 None
 1.04A 5vceA-4hb4C:
undetectable		 5vceA-4hb4C:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		5 / 10 ILE C 907
LEU C 911
LEU C 875
ALA C 873
LEU C 877
 None
 1.27A 5y7pD-4hb4C:
undetectable		 5y7pD-4hb4C:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		5 / 10 ILE C 907
LEU C 911
LEU C 875
ALA C 873
LEU C 877
 None
 1.26A 5y7pH-4hb4C:
undetectable		 5y7pH-4hb4C:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 4hb4 EXPORTIN-1
(Saccharomyces
cerevisiae) 		4 / 8 TYR C 645
GLN C 720
ASN C 706
ILE C 702
 None
 1.07A 6hzpA-4hb4C:
1.9		 6hzpA-4hb4C:
19.05