SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4hbc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JGL_L_ESTL911_1
(IG GAMMA-1-CHAIN
IG KAPPA-CHAIN)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN
ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
LIGHT CHAIN

(Oryctolagus
cuniculus)
5 / 10 GLY H  97
ALA L  34
TYR L  36
LEU L  46
TYR L  49
None
1.03A 1jglH-4hbcH:
23.3
1jglL-4hbcH:
15.0
1jglH-4hbcH:
53.57
1jglL-4hbcH:
27.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HH9_A_VIBA702_1
(THIAMIN
PYROPHOSPHOKINASE)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
LIGHT CHAIN

(Oryctolagus
cuniculus)
5 / 9 TYR L 141
VAL L 197
SER L 178
SER L 163
ASN L 162
None
1.35A 2hh9A-4hbcL:
0.0
2hh9B-4hbcL:
0.0
2hh9A-4hbcL:
20.70
2hh9B-4hbcL:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HH9_B_VIBB701_1
(THIAMIN
PYROPHOSPHOKINASE)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
LIGHT CHAIN

(Oryctolagus
cuniculus)
5 / 9 VAL L 197
SER L 178
SER L 163
ASN L 162
TYR L 141
None
1.35A 2hh9A-4hbcL:
0.0
2hh9B-4hbcL:
0.0
2hh9A-4hbcL:
20.70
2hh9B-4hbcL:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
LIGHT CHAIN

(Oryctolagus
cuniculus)
3 / 3 PHE L  71
TYR L  92
LEU L  47
None
0.70A 3keeB-4hbcL:
undetectable
3keeB-4hbcL:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
4 / 5 LEU H 110
GLN H  38
THR H  89
GLU H 150
None
1.32A 3n58C-4hbcH:
undetectable
3n58C-4hbcH:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
LIGHT CHAIN

(Oryctolagus
cuniculus)
3 / 3 PHE L  71
TYR L  92
LEU L  47
None
0.78A 3sueB-4hbcL:
undetectable
3sueB-4hbcL:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
LIGHT CHAIN

(Oryctolagus
cuniculus)
3 / 3 GLN L 156
THR L 158
THR L 157
None
0.83A 4fu9A-4hbcL:
undetectable
4fu9A-4hbcL:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
LIGHT CHAIN

(Oryctolagus
cuniculus)
3 / 3 GLN L 156
THR L 158
THR L 157
None
0.81A 4fufA-4hbcL:
undetectable
4fufA-4hbcL:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.44A 4qvlV-4hbcH:
undetectable
4qvlb-4hbcH:
undetectable
4qvlV-4hbcH:
21.43
4qvlb-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.44A 4qvlH-4hbcH:
undetectable
4qvlN-4hbcH:
undetectable
4qvlH-4hbcH:
21.43
4qvlN-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.44A 4qvmV-4hbcH:
undetectable
4qvmb-4hbcH:
undetectable
4qvmV-4hbcH:
21.43
4qvmb-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.44A 4qvmH-4hbcH:
undetectable
4qvmN-4hbcH:
undetectable
4qvmH-4hbcH:
21.43
4qvmN-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.45A 4qvpV-4hbcH:
undetectable
4qvpb-4hbcH:
undetectable
4qvpV-4hbcH:
21.43
4qvpb-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.45A 4qvpH-4hbcH:
undetectable
4qvpN-4hbcH:
undetectable
4qvpH-4hbcH:
21.43
4qvpN-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.45A 4qvqV-4hbcH:
undetectable
4qvqb-4hbcH:
undetectable
4qvqV-4hbcH:
21.43
4qvqb-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.45A 4qvqH-4hbcH:
undetectable
4qvqN-4hbcH:
undetectable
4qvqH-4hbcH:
21.43
4qvqN-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 10 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.44A 4qvvV-4hbcH:
undetectable
4qvvb-4hbcH:
undetectable
4qvvV-4hbcH:
21.43
4qvvb-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 10 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.44A 4qvvH-4hbcH:
undetectable
4qvvN-4hbcH:
undetectable
4qvvH-4hbcH:
21.43
4qvvN-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.44A 4qvwV-4hbcH:
undetectable
4qvwb-4hbcH:
undetectable
4qvwV-4hbcH:
21.43
4qvwb-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.45A 4qvwH-4hbcH:
undetectable
4qvwN-4hbcH:
undetectable
4qvwH-4hbcH:
21.43
4qvwN-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.47A 4qvyV-4hbcH:
undetectable
4qvyb-4hbcH:
undetectable
4qvyV-4hbcH:
21.43
4qvyb-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.47A 4qvyH-4hbcH:
undetectable
4qvyN-4hbcH:
undetectable
4qvyH-4hbcH:
21.43
4qvyN-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.44A 4qw0V-4hbcH:
undetectable
4qw0b-4hbcH:
undetectable
4qw0V-4hbcH:
21.43
4qw0b-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.44A 4qw0H-4hbcH:
undetectable
4qw0N-4hbcH:
undetectable
4qw0H-4hbcH:
21.43
4qw0N-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.44A 4qw1V-4hbcH:
undetectable
4qw1b-4hbcH:
undetectable
4qw1V-4hbcH:
21.43
4qw1b-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.44A 4qw1H-4hbcH:
undetectable
4qw1N-4hbcH:
undetectable
4qw1H-4hbcH:
21.43
4qw1N-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.45A 4qw3V-4hbcH:
undetectable
4qw3b-4hbcH:
undetectable
4qw3V-4hbcH:
21.43
4qw3b-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.45A 4qw3H-4hbcH:
undetectable
4qw3N-4hbcH:
undetectable
4qw3H-4hbcH:
21.43
4qw3N-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.44A 4qwuV-4hbcH:
undetectable
4qwub-4hbcH:
undetectable
4qwuV-4hbcH:
21.43
4qwub-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.44A 4qwuH-4hbcH:
undetectable
4qwuN-4hbcH:
undetectable
4qwuH-4hbcH:
21.43
4qwuN-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN
ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
LIGHT CHAIN

(Oryctolagus
cuniculus;
Oryctolagus
cuniculus)
5 / 12 ILE L  48
GLN L   6
TYR L  86
GLN H  38
LEU H  44
None
1.48A 4qztA-4hbcL:
undetectable
4qztA-4hbcL:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.42A 5bxnV-4hbcH:
undetectable
5bxnb-4hbcH:
undetectable
5bxnV-4hbcH:
21.43
5bxnb-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.43A 5bxnH-4hbcH:
undetectable
5bxnN-4hbcH:
undetectable
5bxnH-4hbcH:
21.43
5bxnN-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 9 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.46A 5cz7V-4hbcH:
undetectable
5cz7b-4hbcH:
undetectable
5cz7V-4hbcH:
21.43
5cz7b-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.46A 5cz7H-4hbcH:
undetectable
5cz7N-4hbcH:
undetectable
5cz7H-4hbcH:
21.43
5cz7N-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.44A 5d0xV-4hbcH:
undetectable
5d0xb-4hbcH:
undetectable
5d0xV-4hbcH:
21.43
5d0xb-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.44A 5d0xH-4hbcH:
undetectable
5d0xN-4hbcH:
undetectable
5d0xH-4hbcH:
21.43
5d0xN-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
4 / 7 ALA H  88
THR H  87
VAL H 111
GLU H  85
None
0.71A 5ecmD-4hbcH:
undetectable
5ecmD-4hbcH:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN
ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
LIGHT CHAIN

(Oryctolagus
cuniculus)
4 / 5 TYR L  87
GLY L 103
THR L 104
GLY H 176
None
0.92A 5jlcA-4hbcL:
undetectable
5jlcA-4hbcL:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.46A 5l5fV-4hbcH:
undetectable
5l5fb-4hbcH:
undetectable
5l5fV-4hbcH:
21.43
5l5fb-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.46A 5l5fH-4hbcH:
undetectable
5l5fN-4hbcH:
undetectable
5l5fH-4hbcH:
21.43
5l5fN-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.46A 5l66V-4hbcH:
undetectable
5l66b-4hbcH:
undetectable
5l66V-4hbcH:
21.43
5l66b-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 SER H   6
THR H  74
THR H  73
ALA H  20
THR H  18
None
1.45A 5l66H-4hbcH:
undetectable
5l66N-4hbcH:
undetectable
5l66H-4hbcH:
21.43
5l66N-4hbcH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 12 GLY H 164
SER H 188
THR H 139
LEU H 140
VAL H 193
None
0.95A 5twjA-4hbcH:
undetectable
5twjA-4hbcH:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_A_TRPA501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
LIGHT CHAIN

(Oryctolagus
cuniculus)
5 / 10 ALA L  81
LEU L  78
ASP L  82
VAL L 108
GLY L 110
None
1.47A 5zbdA-4hbcL:
1.0
5zbdA-4hbcL:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_B_TRPB501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
LIGHT CHAIN

(Oryctolagus
cuniculus)
5 / 10 ALA L  81
LEU L  78
ASP L  82
VAL L 108
GLY L 110
None
1.47A 5zbdB-4hbcL:
undetectable
5zbdB-4hbcL:
17.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
LIGHT CHAIN

(Oryctolagus
cuniculus)
4 / 4 VAL L  15
GLY L 110
ASP L 111
ASP L 171
None
0.19A 6cjkC-4hbcL:
28.2
6cjkC-4hbcL:
85.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)
4hbc ANTIGEN BINDING
FRAGMENT,
IMMUNOGLOBULIN IGG -
HEAVY CHAIN

(Oryctolagus
cuniculus)
5 / 11 VAL H 206
THR H 204
VAL H 210
ALA H 120
VAL H 154
None
1.14A 6dryA-4hbcH:
undetectable
6dryA-4hbcH:
15.75